Neuronal Injury Associated with HIV-1 and Potential Treatment with Calcium-Channel and NMDA Antagonists
Lipton S. Neuronal Injury Associated with HIV-1 and Potential Treatment with Calcium-Channel and NMDA Antagonists. Developmental Neuroscience 1994, 16: 145-151. PMID: 7705221, DOI: 10.1159/000112101.Peer-Reviewed Original ResearchConceptsNMDA antagonistsHIV-1HIV-1 envelope protein gp120Existence of HIVBrains of patientsCalcium channel antagonistsVoltage-dependent Ca2Receptor-operated channelsFuture pharmacological interventionsFinal common pathwayAmyotrophic lateral sclerosisEnvelope protein gp120Platelet-activating factorDemise of neuronsInjury AssociatedAIDS dementiaNeuronal injuryGlutamate reuptakeNeurological manifestationsGlutamate releaseImmunodeficiency syndromeChannel antagonistsPharmacological interventionsProtein gp120Lateral sclerosis