2023
Editorial: Gut-liver-brain axis: a complex network influences human health and diseases
Wu H, Zhang Y, Yu J, Shi M. Editorial: Gut-liver-brain axis: a complex network influences human health and diseases. Frontiers In Neuroscience 2023, 17: 1241069. PMID: 37521705, PMCID: PMC10374336, DOI: 10.3389/fnins.2023.1241069.Peer-Reviewed Original Research
2021
Immune normalization strategy against suboptimal health status: safe and efficacious therapy using mixed-natural killer cells
Li Y, Harunori O, Fu S, Xing F, Wu H, Wang J, Chen A, Ren X, Peng D, Ling X, Shi M, Wu H. Immune normalization strategy against suboptimal health status: safe and efficacious therapy using mixed-natural killer cells. Aging 2021, 13: 20131-20148. PMID: 34461606, PMCID: PMC8436936, DOI: 10.18632/aging.203279.Peer-Reviewed Original ResearchMeSH KeywordsAdjuvants, ImmunologicAgedAntigensCD3 ComplexCD56 AntigenCD8-Positive T-LymphocytesCell Culture TechniquesHealth StatusHumansImmune SystemImmunityImmunotherapyKiller Cells, NaturalLeukocytes, MononuclearLymphomaMiddle AgedNeoplasmsPancreatic NeoplasmsProgrammed Cell Death 1 ReceptorReceptors, IgGT-Lymphocytes, Helper-InducerTreatment OutcomeConceptsPeripheral blood mononuclear cellsPD-1<sup>+</sup> T cellsProgrammed cell death protein 1Sub-healthy individualsNKM cellsImmune normalizationT cellsCD8<sup>+</sup>PD-1<sup>+</sup> T cellsCancer patientsCell death protein 1Proportion of NK cellsProportion of T helper cellsPeripheral immune systemT helper cellsBlood mononuclear cellsPotential clinical applicationsMalignant lymphomaNK cellsAdjuvant treatmentKiller cellsPancreatic cancerMononuclear cellsEfficacious therapyCancer preventionSide effects
2019
Single-Cell Intratumoral Stemness Analysis Reveals the Involvement of Cell Cycle and DNA Damage Repair in Two Different Types of Esophageal Cancers
Wu H, Li Y, Hou Q, Zhou R, Li Z, Wu S, Yu J, Jiang M. Single-Cell Intratumoral Stemness Analysis Reveals the Involvement of Cell Cycle and DNA Damage Repair in Two Different Types of Esophageal Cancers. International Journal Of Radiation Oncology • Biology • Physics 2019, 105: s175. DOI: 10.1016/j.ijrobp.2019.06.209.Peer-Reviewed Original Research
2018
Patient Derived Xenografts Demonstrate the Radiosensitizing Effect of Inhibiting MAPK Signaling Pathway in Pancreatic Ductal Adenocarcinoma
Zhang H, Jiang Z, Yue J, Yu J, Wu H, Zhang X, Yang L, Zheng X, Jiang M, Hua Y, Hou Q, Huang M, Li Y, Wu S. Patient Derived Xenografts Demonstrate the Radiosensitizing Effect of Inhibiting MAPK Signaling Pathway in Pancreatic Ductal Adenocarcinoma. International Journal Of Radiation Oncology • Biology • Physics 2018, 102: e188-e189. DOI: 10.1016/j.ijrobp.2018.07.685.Peer-Reviewed Original Research
2017
Targeting CAFs-Secreted TGFβ1 Signaling to Radiosensitize Esophageal Squamous Cell Carcinoma In Vitro and In Vivo
Zhang H, Yue J, Jiang Z, Wu H, Zhang X, Yang L, Jiang M, Hua Y, Li Y, Huang M, Hou Q, Li W, Wu S. Targeting CAFs-Secreted TGFβ1 Signaling to Radiosensitize Esophageal Squamous Cell Carcinoma In Vitro and In Vivo. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: s149. DOI: 10.1016/j.ijrobp.2017.06.346.Peer-Reviewed Original ResearchSingle-Cell Transcriptome Analyses Reveal Taxol Resistant Subpopulations in Esophageal Squamous Cancer Cells
Wu H, Yu J, Chen S, Zhang X, Yang L, Zhang H, Li Y, Hou Q, Hua Y, Jiang M, Wang C, Wu S. Single-Cell Transcriptome Analyses Reveal Taxol Resistant Subpopulations in Esophageal Squamous Cancer Cells. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: e627-e628. DOI: 10.1016/j.ijrobp.2017.06.2115.Peer-Reviewed Original ResearchClonal Evolution of Radioresistance in Esophageal Squamous Cell Carcinoma by Single-Cell Whole Exome Sequencing
Yang L, Zhang X, Wu H, Li Y, Zhang H, Jing Z, Hou Q, Jiang M, Hua Y, Vijay P, Mason C, Wu S. Clonal Evolution of Radioresistance in Esophageal Squamous Cell Carcinoma by Single-Cell Whole Exome Sequencing. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: s198-s199. DOI: 10.1016/j.ijrobp.2017.06.493.Peer-Reviewed Original ResearchSingle-Cell Transcriptome Analyses Reveal Signals to Radio-Resistance in Esophageal Squamous Cell Carcinoma
Wu H, Yang L, Zhang X, Zhang H, Li Y, Hou Q, Jiang Z, Hua Y, Jiang M, Brunicardi C, Yu J, Wu S. Single-Cell Transcriptome Analyses Reveal Signals to Radio-Resistance in Esophageal Squamous Cell Carcinoma. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: e627. DOI: 10.1016/j.ijrobp.2017.06.2114.Peer-Reviewed Original ResearchNVP-BSK805, An Inhibitor of JAK2 Kinase, Significantly Enhances the Radiosensitivity of Esophageal Squamous Cell Carcinoma In Vitro and In Vivo
Zhang H, Luo H, Yang L, Wu H, Hu Z, Jiang M, Hua Y, Li Y, Yue J, Jiang Z, Zhang X, Hou Q, Huang M, Li W, Wu S. NVP-BSK805, An Inhibitor of JAK2 Kinase, Significantly Enhances the Radiosensitivity of Esophageal Squamous Cell Carcinoma In Vitro and In Vivo. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: e630-e631. DOI: 10.1016/j.ijrobp.2017.06.2123.Peer-Reviewed Original Research
2016
CAFs-Promoted LncRNA DNM3OS Conferred Radioresistance by Regulating DNA Damage Response in a TNFSF4-Dependent Manner in Esophageal Squamous Cell Carcinoma
Zhang H, Jiang Z, Yue J, Wu H, Zhang X, Yang L, Li Y, Li S, Hou Q, Wang Y. CAFs-Promoted LncRNA DNM3OS Conferred Radioresistance by Regulating DNA Damage Response in a TNFSF4-Dependent Manner in Esophageal Squamous Cell Carcinoma. International Journal Of Radiation Oncology • Biology • Physics 2016, 96: e583-e584. DOI: 10.1016/j.ijrobp.2016.06.2089.Peer-Reviewed Original ResearchCAFs-Secreted CXCL1 Mediated Radioresistance by Regulating DNA Damage Response in an ROS-Dependent Manner in Esophageal Squamous Cell Carcinoma
Zhang H, Yue J, Jiang Z, Wu H, Zhang X, Yang L, Li Y, Li S, Hou Q, Wang Y, Wu S. CAFs-Secreted CXCL1 Mediated Radioresistance by Regulating DNA Damage Response in an ROS-Dependent Manner in Esophageal Squamous Cell Carcinoma. International Journal Of Radiation Oncology • Biology • Physics 2016, 96: s239. DOI: 10.1016/j.ijrobp.2016.06.593.Peer-Reviewed Original Research