2022
Antiretroviral therapy resistance mutations among HIV infected people in Kazakhstan
Mukhatayeva A, Mustafa A, Dzissyuk N, Issanov A, Mukhatayev Z, Bayserkin B, Vermund SH, Ali S. Antiretroviral therapy resistance mutations among HIV infected people in Kazakhstan. Scientific Reports 2022, 12: 17195. PMID: 36229577, PMCID: PMC9562405, DOI: 10.1038/s41598-022-22163-7.Peer-Reviewed Original Research
2021
Human Immunodeficiency Virus Infection and Incident Heart Failure: A Meta-Analysis of Prospective Studies
Chen Y, Gao Y, Zhou Y, Li X, Wang H, Polonsky TS, Vermund SH, Qian HZ, Qian F. Human Immunodeficiency Virus Infection and Incident Heart Failure: A Meta-Analysis of Prospective Studies. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2021, 87: 741-749. PMID: 33492019, PMCID: PMC10768809, DOI: 10.1097/qai.0000000000002629.Peer-Reviewed Original ResearchConceptsIncident heart failureLow CD4 countHeart failureHIV infectionRandom-effects modelCD4 countSubgroup analysisRisk of HFHuman immunodeficiency virus (HIV) infectionLaird random-effects modelYoung adultsAvailable prospective evidenceImmunodeficiency virus infectionPooled relative riskFull-text assessmentWeb of ScienceFixed-effects modelProspective studyIncident casesProspective evidenceRelative riskVirus infectionFunnel plotMeta-AnalysisSimilar association
2017
Mortality in Children with Human Immunodeficiency Virus Initiating Treatment: A Six-Cohort Study in Latin America
Luque MT, Jenkins CA, Shepherd BE, Padgett D, Rouzier V, Succi RCM, Machado DM, McGowan CC, Vermund SH, Pinto JA. Mortality in Children with Human Immunodeficiency Virus Initiating Treatment: A Six-Cohort Study in Latin America. The Journal Of Pediatrics 2017, 182: 245-252.e1. PMID: 28081884, PMCID: PMC5328796, DOI: 10.1016/j.jpeds.2016.12.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCause of DeathChildChild, PreschoolCohort StudiesConfidence IntervalsDatabases, FactualDose-Response Relationship, DrugDrug Administration ScheduleFemaleHIV InfectionsHumansIncidenceLatin AmericaMaleProportional Hazards ModelsRetrospective StudiesRisk AssessmentSeverity of Illness IndexSurvival AnalysisConceptsCombination antiretroviral therapyYears of ageCART initiationGreater riskCox proportional hazards modelAntiretroviral therapy-naïveMedian CD4 countRetrospective cohort studyProportional hazards modelCumulative mortality incidenceSouth America networkProbability of deathInitiating treatmentMedian CD4Antiretroviral therapyCause mortalityCD4 countTherapy-naïveCohort studyCumulative incidenceHIV epidemiologyPediatric careMortality incidenceHazards modelRegimens
2016
Rates and determinants of incidence and clearance of cervical HPV genotypes among HIV-seropositive women in Pune, India
Mane A, Sahasrabuddhe VV, Nirmalkar A, Risbud AR, Sahay S, Bhosale RA, Vermund SH, Mehendale SM. Rates and determinants of incidence and clearance of cervical HPV genotypes among HIV-seropositive women in Pune, India. Journal Of Clinical Virology 2016, 88: 26-32. PMID: 28152432, PMCID: PMC5441893, DOI: 10.1016/j.jcv.2016.10.013.Peer-Reviewed Original ResearchConceptsHIV-seropositive womenCervical HPV genotypesHPV genotypesClearance rateHPV infectionAge-related hormonal changesRoche Linear Array HPVAlpha-7 speciesAntiretroviral therapy statusCarcinogenic HPV genotypesCervical HPV infectionGenotype-specific prevalenceLinear Array HPVAge of participantsCD4 countHPV incidenceImmunologic factorsDeterminants of incidenceHPV typesTherapy statusProspective studyCervical samplesIncidence rateHormonal changesEtiologic studies
2015
Predictors of antiretroviral therapy initiation: a cross-sectional study among Chinese HIV-infected men who have sex with men
Liu Y, Ruan Y, Vermund SH, Osborn CY, Wu P, Jia Y, Shao Y, Qian HZ. Predictors of antiretroviral therapy initiation: a cross-sectional study among Chinese HIV-infected men who have sex with men. BMC Infectious Diseases 2015, 15: 570. PMID: 26714889, PMCID: PMC4696158, DOI: 10.1186/s12879-015-1309-x.Peer-Reviewed Original ResearchConceptsCells/μLAntiretroviral therapy initiationART initiationHIV infectionCross-sectional studyTherapy initiationChinese MSMWorld Health Organization (WHO) clinical stage III/IVClinical stage III/IVStage III/IVNational HIV treatment guidelinesCD4 cell countHIV treatment guidelinesHIV viral suppressionLonger durationLogistic regression modelsChinese HIVEligible HIVCD4 countHIV careViral suppressionART eligibilityMedian durationTreatment guidelinesClinical symptoms
2014
Current drug use and lack of HIV virologic suppression: point-of-care urine drug screen versus self-report
Qian HZ, Mitchell VJ, Bebawy S, Cassell H, Perez G, McGowan CC, Sterling TR, Vermund SH, D’Aquila R, Hulgan T. Current drug use and lack of HIV virologic suppression: point-of-care urine drug screen versus self-report. BMC Infectious Diseases 2014, 14: 508. PMID: 25234368, PMCID: PMC4175271, DOI: 10.1186/1471-2334-14-508.Peer-Reviewed Original ResearchConceptsUrine drug screensCurrent drug usePositive urine drug screenComputer Assisted Self-InterviewVirologic suppressionDrug useAntiretroviral therapyDrug screensNegative urine drug screensHigher CD4 countsHIV disease progressionRoutine clinic visitsHIV virologic suppressionCross-sectional studyLower self-reported ratesSelf-reported ratesCD4 countClinic visitsPrognostic informationDisease progressionCaucasian raceART usersLower likelihoodResultsAbout halfSelf interviewRisk Factors for Delayed Initiation of Combination Antiretroviral Therapy in Rural North Central Nigeria
Aliyu MH, Blevins M, Parrish DD, Megazzini KM, Gebi UI, Muhammad MY, Ahmed ML, Hassan A, Shepherd BE, Vermund SH, Wester CW. Risk Factors for Delayed Initiation of Combination Antiretroviral Therapy in Rural North Central Nigeria. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 65: e41-e49. PMID: 23727981, PMCID: PMC3818360, DOI: 10.1097/qai.0b013e31829ceaec.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyAntiretroviral therapyDate of enrollmentART initiationCD4 countFunctional statusInitiation of ARTMedian CD4 countHigher CD4 countsLower functional statusMonths of enrollmentBody mass indexART eligibility criteriaAdults/adolescentsRural North-Central NigeriaHIV/AIDSQuality improvement effortsEligible HIVEligible patientsPatient characteristicsART uptakeMass indexRisk factorsTimely initiationDelayed initiation
2011
Contemporary profile of oral manifestations of HIV/AIDS and associated risk factors in a southeastern US clinic
Tamí‐Maury I, Willig J, Vermund S, Jolly P, Aban I, Hill J, Wilson CM. Contemporary profile of oral manifestations of HIV/AIDS and associated risk factors in a southeastern US clinic. Journal Of Public Health Dentistry 2011, 71: 257-264. PMID: 22320283, DOI: 10.1111/j.1752-7325.2011.00256.x.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdultAIDS-Related Opportunistic InfectionsAntiretroviral Therapy, Highly ActiveBlack or African AmericanCandidiasis, OralCD4 Lymphocyte CountCohort StudiesFemaleFollow-Up StudiesHeterosexualityHIV InfectionsHIV-1Homosexuality, MaleHumansMaleMouth DiseasesOropharynxPharyngeal DiseasesPrevalenceRetrospective StudiesRisk FactorsSex FactorsSoutheastern United StatesViral LoadYoung AdultConceptsOral manifestationsOropharyngeal candidiasisRisk factorsUS clinicsHIV-1 RNA viral loadLow baseline CD4 countBaseline CD4 valueMean baseline CD4Active antiretroviral therapyBaseline CD4 countRNA viral loadHIV-positive individualsHIV/AIDSLogistic regression modelsBaseline CD4Antiretroviral therapyCD4 countLaboratory characteristicsRetrospective reviewCD4 valuesViral loadHIV prevalenceMean ageT cellsHAART
2007
Influence of body mass index on pregnancy outcomes among HIV‐infected and HIV‐uninfected Zambian women
Banda Y, Chapman V, Goldenberg RL, H. B, Vermund SH, Stringer JS. Influence of body mass index on pregnancy outcomes among HIV‐infected and HIV‐uninfected Zambian women. Tropical Medicine And International Health 2007, 12: 856-861. PMID: 17596253, PMCID: PMC2570322, DOI: 10.1111/j.1365-3156.2007.01857.x.Peer-Reviewed Original ResearchConceptsBody mass indexPregnancy outcomesBirth weightInfant weightMass indexZambian womenBMI unitsLower body mass indexChild transmission ratePerinatal HIV transmissionPrevention of motherHIV viral loadInfant birth weightMean birth weightTransmission of HIVNevirapine administrationPrior stillbirthBMI quartilesCD4 countChild transmissionViral loadHIV transmissionMaternal parityUnivariate analysisClinical trialsComplete Blood Cell Count as a Surrogate CD4 Cell Marker for HIV Monitoring in Resource-Limited Settings
Chen RY, Westfall AO, Hardin JM, Miller-Hardwick C, Stringer JS, Raper JL, Vermund SH, Gotuzzo E, Allison J, Saag MS. Complete Blood Cell Count as a Surrogate CD4 Cell Marker for HIV Monitoring in Resource-Limited Settings. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2007, 44: 525-530. PMID: 17259910, DOI: 10.1097/qai.0b013e318032385e.Peer-Reviewed Original ResearchConceptsBirmingham Veterans Affairs Medical CenterTotal lymphocyte countCells/microLCD4 countVeterans Affairs Medical CenterComplete blood cell countAntiretroviral treatment statusLow CD4 cellsBody mass indexBlood cell countCells/Receiver operator characteristic curveResource limited settingsObservational databaseResource-limited settingsCD4 cellsLymphocyte count
1993
Depressive Symptoms as Predictors of Medical Outcomes in HIV Infection
Lyketsos C, Hoover D, Guccione M, Senterfitt W, Dew M, Wesch J, VanRaden M, Treisman G, Morgenstern H, Saah A, Palenicek J, Armenian H, Farzadegan H, Graham N, Margolick J, McArthur J, Phair J, Chmiel J, Cohen B, O'Gorman M, Variakojis D, Wesch J, Wolinsky S, Detels R, Visscher B, Chen I, Dudley J, Fahey J, Giorgi J, Lee M, Martinez-Mara O, Miller E, Nishanian P, Taylor J, Zack J, Rinaldor C, Kingsley L, Becker J, Gupta P, Ho M, Muñoz A, Jacobson L, Beaty T, Galai N, Epstein L, Guccione M, Hoover D, Meinert C, Nelson K, Piantadosi S, Su S, Schrager L, Vermund S, Kaslow R, VanRaden M, Seminara D. Depressive Symptoms as Predictors of Medical Outcomes in HIV Infection. JAMA 1993, 270: 2563-2567. DOI: 10.1001/jama.1993.03510210049026.Peer-Reviewed Original ResearchHuman immunodeficiency virusCD4 countCohort studyHIV infectionDepressive symptomsMedical outcomesEight-year cohort studyHIV-seropositive homosexual menMulticenter AIDS Cohort StudyLow CD4 countEpidemiologic Studies Depression ScaleAssociation of depressionEight-year followWorse medical outcomesAIDS Cohort StudyHIV outcomesImmunodeficiency syndromeImmunodeficiency virusProphylactic treatmentEligible participantsWorse outcomesMore AIDSOutcome measuresHomosexual menSymptoms