2024
Impacts of resident physician unionization on house staff compensation
Tyagi S, Shah R, Huttler J, Kayani J, Ghovanloo M, Effraim P. Impacts of resident physician unionization on house staff compensation. PLOS ONE 2024, 19: e0308100. PMID: 39361626, PMCID: PMC11449312, DOI: 10.1371/journal.pone.0308100.Peer-Reviewed Original ResearchConceptsNon-union counterpartsPhysician unionsWorking long hoursUnion statusResidency training programsUnion programCost-of-livingLow wagesStaff compensationLong hoursTraining programSalaryInternal medicine residency training programsPhysicians-in-trainingRegional factorsDisbursementBenefit dataCross-sectional investigationMonetary benefitsUnionResident salariesCompensationCost-of-living differencesPGY-1Residency programs
2023
Extra imaging beyond NCCN surveillance guidelines is cost effective for HPV− but not HPV+ oropharyngeal cancer
Shah R, Tyagi S, Liu C, Judson B. Extra imaging beyond NCCN surveillance guidelines is cost effective for HPV− but not HPV+ oropharyngeal cancer. Oral Oncology 2023, 146: 106564. PMID: 37672950, DOI: 10.1016/j.oraloncology.2023.106564.Peer-Reviewed Original Research
2022
The fates of internalized NaV1.7 channels in sensory neurons: Retrograde cotransport with other ion channels, axon-specific recycling, and degradation
Higerd-Rusli G, Tyagi S, Liu S, Dib-Hajj F, Waxman S, Dib-Hajj S. The fates of internalized NaV1.7 channels in sensory neurons: Retrograde cotransport with other ion channels, axon-specific recycling, and degradation. Journal Of Biological Chemistry 2022, 299: 102816. PMID: 36539035, PMCID: PMC9843449, DOI: 10.1016/j.jbc.2022.102816.Peer-Reviewed Original ResearchConceptsMembrane proteinsIon channelsNeuronal functionDistinct neuronal compartmentsAxonal membrane proteinsRetrograde traffickingNeuronal polarityRecycling pathwayLate endosomesPlasma membraneSpecific proteinsAxonal traffickingNovel mechanismCell membraneSodium channel NaNeuronal compartmentsMultiple pathwaysLive neuronsVoltage-gated sodium channel NaProteinEndocytosisMembrane specializationsTraffickingMembraneChannel NaComplex effects on CaV2.1 channel gating caused by a CACNA1A variant associated with a severe neurodevelopmental disorder
Grosso B, Kramer A, Tyagi S, Bennett D, Tifft C, D’Souza P, Wangler M, Macnamara E, Meza U, Bannister R. Complex effects on CaV2.1 channel gating caused by a CACNA1A variant associated with a severe neurodevelopmental disorder. Scientific Reports 2022, 12: 9186. PMID: 35655070, PMCID: PMC9163077, DOI: 10.1038/s41598-022-12789-y.Peer-Reviewed Original ResearchConceptsCongenital ataxiaQ-type Ca2Function mutationsSevere neurodevelopmental disorderTsA-201 cellsCerebral edemaFocal seizuresCaV2.1 channelsCentral synapsesChannel dysfunctionNeurological disordersNeuromuscular junctionCACNA1A variantsNeurotransmitter releaseΑ1A subunitAction potential-like stimuliReversal potentialNeurodevelopmental disordersComplex functional effectsFunctional effectsDisordersAtaxiaMissense mutationsCa2Channel gating
2017
Semi-automated Analysis of Mouse Skeletal Muscle Morphology and Fiber-type Composition.
Tyagi S, Beqollari D, Lee CS, Walker LA, Bannister RA. Semi-automated Analysis of Mouse Skeletal Muscle Morphology and Fiber-type Composition. Journal Of Visualized Experiments 2017 PMID: 28892032, PMCID: PMC5614392, DOI: 10.3791/56024.Peer-Reviewed Original Research