2024
Critical Assessment of Fellowship Director Gender and Ethnic Diversity across the Five Major Plastic Surgery Fellowships
Boroumand S, Stogniy S, Katsnelson B, Allam O, Vafa A, Sullivan J, Pomahac B, Haykal S, Butler P. Critical Assessment of Fellowship Director Gender and Ethnic Diversity across the Five Major Plastic Surgery Fellowships. Plastic & Reconstructive Surgery Global Open 2024, 12: e6286. PMID: 39600330, PMCID: PMC11596926, DOI: 10.1097/gox.0000000000006286.Peer-Reviewed Original ResearchFellowship directorsMentorship of traineesFellowship programsPatient populationReconstructive surgeryPlastic surgery fellowshipsProfessional society websitesSurgical workforcePercentage of malesMicrosurgerySociety websitesDirector demographicsFellowshipSurgeryPatientsFemale directorsRacial/ethnic minoritiesLong-term Posttransplant-Related Bone Volumetric Changes in Eight Face Transplant Recipients – a Single Center Retrospective Case Series
Huelsboemer L, Boroumand S, Boroumand T, Vafa A, Parikh N, Chiarella L, Knoedler L, Stögner V, Hung P, Sadigh S, Haykal S, Pomahac B, Kauke-Navarro M. Long-term Posttransplant-Related Bone Volumetric Changes in Eight Face Transplant Recipients – a Single Center Retrospective Case Series. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024 DOI: 10.1016/j.bjps.2024.11.025.Peer-Reviewed Original ResearchFacial vascularized composite allograftBone volume changesBone volumeChronic rejection processRetrospective case seriesComputed tomography scanBone volume lossWilcoxon rank sum testNative boneSignificant median decreaseBone volume stabilityRank sum testFace transplant recipientsBone remodeling ratesVascularized composite allograftsChronic immunosuppressionTooth lossTransplant recipientsAllograft cohortCase seriesTomography scanVolume lossMedian decreaseMedical comorbiditiesHistopathological analysisEvaluating two decades of traumatic amputations treated in US emergency departments: A multicenter epidemiological analysis from NEISS
Boroumand S, Ajjawi I, Park N, Huelsboemer L, Stögner V, Bach K, Kauke-Navarro M, Haykal S, Pomahac B, Colen D. Evaluating two decades of traumatic amputations treated in US emergency departments: A multicenter epidemiological analysis from NEISS. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024, 99: 63-66. PMID: 39353285, DOI: 10.1016/j.bjps.2024.09.068.Peer-Reviewed Original ResearchReading Between the Tabloids: An Objective Analysis of the Quality and Readability of Patient Encountered Online Material for Face Transplantation.
Boroumand S, Littleton A, Aregbe A, Gu E, Huelsboemer L, Stögner V, Lewis K, Kauke-Navarro M, Haykal S, Pomahac B. Reading Between the Tabloids: An Objective Analysis of the Quality and Readability of Patient Encountered Online Material for Face Transplantation. Journal Of Craniofacial Surgery 2024 PMID: 39471279, DOI: 10.1097/scs.0000000000010668.Peer-Reviewed Original ResearchNews sourcesOnline materialsNewsFace transplant programsThird-party sourcesReadability metricsFace transplantationReadabilityTransplant programsPost hoc Tukey multiple comparison testTukey's multiple comparison testMultiple comparison testReputable sourcesTabloidsReadability of online materialsAuthorshipOne-way ANOVATransplantationThird-party sitesJAMA benchmark criteriaDiscernmentEncountersJAMA benchmarksTwo Decades of Advances and Limitations in Organ Recellularization
Stoian A, Adil A, Biniazan F, Haykal S. Two Decades of Advances and Limitations in Organ Recellularization. Current Issues In Molecular Biology 2024, 46: 9179-9214. PMID: 39194760, PMCID: PMC11352560, DOI: 10.3390/cimb46080543.Peer-Reviewed Original ResearchThe Role of Negative Pressure Wound Therapy in Temporizing Traumatic Wounds before Lower Limb Soft Tissue Reconstruction: A Systematic Review
Barone N, Ziolkowski N, Haykal S. The Role of Negative Pressure Wound Therapy in Temporizing Traumatic Wounds before Lower Limb Soft Tissue Reconstruction: A Systematic Review. Plastic & Reconstructive Surgery Global Open 2024, 12: e6003. PMID: 39071768, PMCID: PMC11281775, DOI: 10.1097/gox.0000000000006003.Peer-Reviewed Original ResearchSoft tissue reconstructionSoft tissue coverageWound therapyTissue reconstructionTissue coverageFlap loss rateComprehensive search of MEDLINEDelayed union rateNegative pressure wound therapyDefinitive soft tissue coverageFollow-up lengthLeg woundsAdult surgical patientsSystematic reviewDefinitive soft tissue reconstructionSearch of MEDLINERisk of bias assessmentTemporal woundTraumatic woundsAdult patientsSurgical patientsNonunion rateBone unionUnion rateCochrane LibraryAdvances in Ischemia Reperfusion Injury Prevention in Free Flaps and Vascularized Composite Allotransplantation
Hadzimustafic N, D’Elia A, Duru C, Haykal S. Advances in Ischemia Reperfusion Injury Prevention in Free Flaps and Vascularized Composite Allotransplantation. Cardiology And Cardiovascular Medicine 2024, 4 DOI: 10.5772/intechopen.112993.Peer-Reviewed Original ResearchIschemia-reperfusion injuryVascularized composite allotransplantationFree flapsStatic cold storagePharmacological strategiesAdvanced reconstructive optionsAttenuation of ischemia-reperfusion injuryIrreversible ischemic damagePost-operative monitoringStem cell strategiesPre-clinical studiesPlastic and Reconstructive SurgeryPost-ischemic periodPost-ischemicReperfusion injuryReconstructive optionsIschemia-reperfusionPre-ischemicReconstructive surgeryIschemic periodPre-ischemic periodIschemic damageClinical toolFlapMachine perfusionImmediate DIEP Breast Reconstruction in a Trans Woman with Breast Cancer
Avery E, Barone N, Haykal S. Immediate DIEP Breast Reconstruction in a Trans Woman with Breast Cancer. Plastic & Reconstructive Surgery Global Open 2024, 12: e5834. PMID: 38798942, PMCID: PMC11124744, DOI: 10.1097/gox.0000000000005834.Peer-Reviewed Original ResearchImmediate breast reconstructionBreast reconstructionBreast cancerEstrogen therapyRisk of breast cancerTrans womenBilateral skin-sparing mastectomyDeep inferior epigastric perforator free flapHistory of estrogen therapySentinel lymph node biopsyManagement of breast cancerDIEP breast reconstructionPostoperative flap complicationsSkin-sparing mastectomyLymph node biopsyLymph node involvementRight breast cancerInvasive mucinous carcinomaBreast cancer diagnosisFree flap reconstructionBreast cancer managementHolistic treatment approachPerforator free flapFinal pathologyNode biopsyIn silico model development and optimization of in vitro lung cell population growth
Mostofinejad A, Romero D, Brinson D, Marin-Araujo A, Bazylak A, Waddell T, Haykal S, Karoubi G, Amon C. In silico model development and optimization of in vitro lung cell population growth. PLOS ONE 2024, 19: e0300902. PMID: 38748626, PMCID: PMC11095723, DOI: 10.1371/journal.pone.0300902.Peer-Reviewed Original ResearchImmune modulation in transplant medicine: a comprehensive review of cell therapy applications and future directions
Knoedler L, Dean J, Diatta F, Thompson N, Knoedler S, Rhys R, Sherwani K, Ettl T, Mayer S, Falkner F, Kilian K, Panayi A, Iske J, Safi A, Tullius S, Haykal S, Pomahac B, Kauke-Navarro M. Immune modulation in transplant medicine: a comprehensive review of cell therapy applications and future directions. Frontiers In Immunology 2024, 15: 1372862. PMID: 38650942, PMCID: PMC11033354, DOI: 10.3389/fimmu.2024.1372862.Peer-Reviewed Original ResearchConceptsRegulatory myeloid cellsSolid organ transplantationVascularized composite allotransplantationMesenchymal stromal cellsT cellsTransplant patientsCellular therapyChimeric antigen receptor T cellsTransplant surgerySide effectsIncreased risk of malignancyProgression to chronic rejectionAcute rejection ratesPerioperative treatment strategiesRegulatory T cellsPromote immune toleranceRisk of malignancySystemic side effectsRelated side effectsCell typesImprove transplant survivalCAR-TCell therapy applicationsImmunosuppressive regimensChronic rejectionBioengineering of vascularized porcine flaps using perfusion-recellularization
Xu M, D’Elia A, Hadzimustafic N, Adil A, Karoubi G, Waddell T, Haykal S. Bioengineering of vascularized porcine flaps using perfusion-recellularization. Scientific Reports 2024, 14: 7590. PMID: 38555385, PMCID: PMC10981729, DOI: 10.1038/s41598-024-58095-7.Peer-Reviewed Original ResearchConceptsLow-concentration sodium dodecyl sulfateAcellular scaffoldsRecellularization techniquesPerfusion-decellularizationMesenchymal stromal cellsSodium dodecyl sulfateCell attachmentRecellularization approachCo-culture of human umbilical vein endothelial cellsRecellularizationHuman umbilical vein endothelial cellsReconstructive surgeryTensor fasciae lataeExtracellular matrixRepair optionsDonor site morbidityImpact patient qualityDodecyl sulfateClinically translatable optionTensor fascia lata flapUmbilical vein endothelial cellsSoft tissue defectsPorcine flapsAdipose-Derived Stem Cells: Angiogenetic Potential and Utility in Tissue Engineering
Biniazan F, Stoian A, Haykal S. Adipose-Derived Stem Cells: Angiogenetic Potential and Utility in Tissue Engineering. International Journal Of Molecular Sciences 2024, 25: 2356. PMID: 38397032, PMCID: PMC10889096, DOI: 10.3390/ijms25042356.Peer-Reviewed Original ResearchImmunogenicity and tolerance induction in vascularized composite allotransplantation
Sun J, Adil A, Biniazan F, Haykal S. Immunogenicity and tolerance induction in vascularized composite allotransplantation. Frontiers In Transplantation 2024, 3: 1350546. PMID: 38993748, PMCID: PMC11235364, DOI: 10.3389/frtra.2024.1350546.Peer-Reviewed Original ResearchHuman-Induced Pluripotent Stem Cells in Plastic and Reconstructive Surgery
Hadzimustafic N, D’Elia A, Shamoun V, Haykal S. Human-Induced Pluripotent Stem Cells in Plastic and Reconstructive Surgery. International Journal Of Molecular Sciences 2024, 25: 1863. PMID: 38339142, PMCID: PMC10855589, DOI: 10.3390/ijms25031863.Peer-Reviewed Original Research
2023
Mesenchymal cells support the early retention of primary alveolar type 2 cells on acellular mouse lung scaffolds
Taniguchi D, Ahmadipour M, Eiliazadeh A, Duchesneau P, Nagayasu T, Haykal S, Karoubi G, Waddell T. Mesenchymal cells support the early retention of primary alveolar type 2 cells on acellular mouse lung scaffolds. Regenerative Therapy 2023, 25: 92-100. PMID: 38204599, PMCID: PMC10776435, DOI: 10.1016/j.reth.2023.11.011.Peer-Reviewed Original ResearchReview of machine perfusion studies in vascularized composite allotransplant preservation
Duru Ç, Biniazan F, Hadzimustafic N, D'Elia A, Shamoun V, Haykal S. Review of machine perfusion studies in vascularized composite allotransplant preservation. Frontiers In Transplantation 2023, 2: 1323387. PMID: 38993931, PMCID: PMC11235328, DOI: 10.3389/frtra.2023.1323387.Peer-Reviewed Original ResearchEvaluation of a decellularized bronchial patch transplant in a porcine model
Taniguchi D, Kamata S, Rostami S, Tuin S, Marin-Araujo A, Guthrie K, Petersen T, Waddell T, Karoubi G, Keshavjee S, Haykal S. Evaluation of a decellularized bronchial patch transplant in a porcine model. Scientific Reports 2023, 13: 21773. PMID: 38066170, PMCID: PMC10709302, DOI: 10.1038/s41598-023-48643-y.Peer-Reviewed Original Research“P 6 LAND”: An Educational Tool for Free Flaps
Ziolkowski N, Haykal S. “P 6 LAND”: An Educational Tool for Free Flaps. Journal Of Reconstructive Microsurgery Open 2023, 08: e97-e113. DOI: 10.1055/s-0043-1777098.Peer-Reviewed Original ResearchThree Ds for diagnosing necrotizing fasciitis by front-line clinicians
Haykal S, Hadzimustafic N, Ghazarian D, Musgrave M. Three Ds for diagnosing necrotizing fasciitis by front-line clinicians. Journal Of Plastic Reconstructive & Aesthetic Surgery 2023, 84: 37-46. PMID: 37320950, DOI: 10.1016/j.bjps.2023.05.020.Peer-Reviewed Original Research122. Procurement and Preservation by Ex Vivo Perfusion of Porcine Hindlimbs for Vascularized Composite Allotransplantation
Hadzimustafic N, D’Elia A, Haykal S. 122. Procurement and Preservation by Ex Vivo Perfusion of Porcine Hindlimbs for Vascularized Composite Allotransplantation. Plastic & Reconstructive Surgery Global Open 2023, 11: 76-77. PMCID: PMC10194549, DOI: 10.1097/01.gox.0000938076.94708.8b.Peer-Reviewed Original Research