High-resolution two-photon transcranial imaging of brain using direct wavefront sensing
Chen C, Qin Z, He S, Liu S, Lau S, Wu W, Zhu D, Ip N, Qu J. High-resolution two-photon transcranial imaging of brain using direct wavefront sensing. Photonics Research 2021, 9: 1144. DOI: 10.1364/prj.420220.Peer-Reviewed Original ResearchTwo-photon microscope systemLiving brain of Alzheimer’s diseaseWavefront sensing algorithmSpatial resolutionThinned-skullImage contrastTwo-photon microscopyMicroscope systemOptical heterogeneitySkull techniqueAccurate correctionImaging depthLayer 5 pyramidal neuronsCortex of miceActive immune responseResolutionMinimally invasive toolSkull windowImaging of brainImmune response