Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer’s disease mouse model
Lau S, Wu W, Seo H, Fu A, Ip N. Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer’s disease mouse model. STAR Protocols 2021, 2: 100265. PMID: 33490981, PMCID: PMC7811161, DOI: 10.1016/j.xpro.2020.100265.Peer-Reviewed Original ResearchConceptsDeposition of extracellular amyloid-betaDisease mouse modelExtracellular amyloid-betaAlzheimer's disease mouse modelAmyloid-betaFlow cytometry-based methodPhagocytic capacityMicroglial phagocytosisMicroglial subpopulationsAlzheimer's diseaseDownstream applicationsAlzheimerMouse modelPhagocytic microgliaIsolatesPhagocytosis