2024
The Role of Angiopoietins in Cardiovascular Outcomes of Kidney Transplant Recipients: An Ancillary Study from the FAVORIT
Gendy N, Brown L, Staunton M, Garg K, Hernandez Garcilazo N, Qian L, Yamamoto Y, Ugwuowo U, Obeid W, Al-Qusairi L, Bostom A, Mansour S. The Role of Angiopoietins in Cardiovascular Outcomes of Kidney Transplant Recipients: An Ancillary Study from the FAVORIT. American Journal Of Nephrology 2024, 55: 597-606. PMID: 38735283, PMCID: PMC11444892, DOI: 10.1159/000538878.Peer-Reviewed Original ResearchKidney transplant recipientsRisk of cardiovascular diseaseGraft failureCardiovascular disease developmentAngpt-2Cardiovascular diseaseIncreased risk of future CVDAncillary studiesClinical variablesCare of kidney transplant recipientsIncreased riskRisk of future CVDUrine albumin-to-creatinine ratioDonor kidney transplant recipientsAlbumin-to-creatinine ratioIncreased risk of cardiovascular diseaseFuture cardiovascular diseaseImproves prediction of cardiovascular diseaseTransplant-related variablesAssociated with outcomeParticipants' median ageMitigate CVD riskMedian ageTransplant recipientsMedian time
2022
Angiopoietins as Prognostic Markers for Future Kidney Disease and Heart Failure Events after Acute Kidney Injury
Mansour SG, Bhatraju PK, Coca SG, Obeid W, Wilson FP, Stanaway IB, Jia Y, Thiessen-Philbrook H, Go AS, Ikizler TA, Siew ED, Chinchilli VM, Hsu CY, Garg AX, Reeves WB, Liu KD, Kimmel PL, Kaufman JS, Wurfel MM, Himmelfarb J, Parikh SM, Parikh CR. Angiopoietins as Prognostic Markers for Future Kidney Disease and Heart Failure Events after Acute Kidney Injury. Journal Of The American Society Of Nephrology 2022, 33: 613-627. PMID: 35017169, PMCID: PMC8975075, DOI: 10.1681/asn.2021060757.Peer-Reviewed Original ResearchConceptsCKD progressionHeart failureLower riskAngpt-1Highest quartileFuture kidney diseaseSetting of AKIAcute kidney injuryHeart failure admissionsHeart failure eventsProspective cohort studyMortality 3 monthsPlasma angiopoietinsKidney injuryCohort studySecondary outcomesEndothelial injuryMedian agePrimary outcomeKidney diseasePrognostic markerAngiopoietin-2AKIAngiopoietin-1Vessel destabilization