2015
Association mapping by pooled sequencing identifies TOLL 11 as a protective factor against Plasmodium falciparum in Anopheles gambiae
Redmond S, Eiglmeier K, Mitri C, Markianos K, Guelbeogo W, Gneme A, Isaacs A, Coulibaly B, Brito-Fravallo E, Maslen G, Mead D, Niare O, Traore S, Sagnon N, Kwiatkowski D, Riehle M, Vernick K. Association mapping by pooled sequencing identifies TOLL 11 as a protective factor against Plasmodium falciparum in Anopheles gambiae. BMC Genomics 2015, 16: 779. PMID: 26462916, PMCID: PMC4603968, DOI: 10.1186/s12864-015-2009-z.Peer-Reviewed Original ResearchConceptsGenetic mappingFounder coloniesHigh nucleotide diversityNon-model genomesLow linkage disequilibriumPhenotype-genotype mappingPopulation stratificationParasite infection levelsHuman malaria parasiteGenotyping of SNPsNucleotide diversityPooled sequencesAssociation mappingGenomic lociLinkage mappingPlasmodium falciparumSignificant SNPsMosquito systemMarker densityDNA poolsAnopheles gambiaeNatural variationIndividual mosquitoesLinkage disequilibriumSequencing identifies
2012
Transcriptome of the adult female malaria mosquito vector Anopheles albimanus
Martínez-Barnetche J, Gómez-Barreto R, Ovilla-Muñoz M, Téllez-Sosa J, López D, Dinglasan R, Mohien C, MacCallum R, Redmond S, Gibbons J, Rokas A, Machado C, Cazares-Raga F, González-Cerón L, Hernández-Martínez S, López M. Transcriptome of the adult female malaria mosquito vector Anopheles albimanus. BMC Genomics 2012, 13: 207. PMID: 22646700, PMCID: PMC3442982, DOI: 10.1186/1471-2164-13-207.Peer-Reviewed Original ResearchConceptsMalaria vectorsProtein-coding transcriptsAvailable genomic informationPlasmodium-mosquito interactionsHigh-quality assemblyImportant malaria vectorAnopheles albimanusFemale transcriptomesPutative orthologsDivergence timesPlasmodium lifecycleEukaryotic genomesTranscriptome projectsEvolutionary biologyInterPro annotationProtein familyMosquito biologyInsect vectorsGenomic informationNeotropical vectorsCDNA libraryIllumina sequencesAnopheline mosquito vectorsGenus AnophelesFat body
2011
An expression map for Anopheles gambiae
MacCallum R, Redmond S, Christophides G. An expression map for Anopheles gambiae. BMC Genomics 2011, 12: 620. PMID: 22185628, PMCID: PMC3341590, DOI: 10.1186/1471-2164-12-620.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnophelesCarrier ProteinsChromosome MappingDefensinsGene Expression ProfilingGenomeInsect ProteinsReceptors, OdorantTranscriptomeConceptsPeptidoglycan recognition proteinsGene familyAnopheles gambiaeGene expressionA. gambiaeIndividual gene clustersMosquito Anopheles gambiaeDistinct biological contextsImmunity-related genesHouse-keeping roleSystems-level viewEvolutionary historyMolecular functionsGene clusterMost organismsTranscriptome dataIndividual genesDistinct functional groupsDNA replicationRecognition proteinsExpression mapProtein degradationPathogen recognitionBiological contextProtein products