2018
Safety of lumbar puncture procedure in an international research setting during acute HIV infection
Chan P, Hellmuth J, Colby D, Kroon E, Sacdalan C, Fletcher J, Patel P, Pinyakorn S, Valcour V, Ananworanich J, Spudich S. Safety of lumbar puncture procedure in an international research setting during acute HIV infection. Journal Of Virus Eradication 2018, 4: 16-20. PMID: 29568548, PMCID: PMC5851179, DOI: 10.1016/s2055-6640(20)30236-3.Peer-Reviewed Original ResearchPost-lumbar puncture headacheAcute HIV infectionCombination antiretroviral therapyBody mass indexLumbar punctureHIV infectionAtraumatic needlesCerebrospinal fluidCSF HIV viral loadHigher body mass indexT-lymphocyte countsAcute retroviral syndromeHIV viral loadFrequency of PPHCerebrospinal fluid volumeLumbar puncture procedureCART initiationAntiretroviral therapyLymphocyte countMass indexViral loadPuncture headacheClinical recordsLongitudinal visitsSubgroup analysis
2008
Failure of atorvastatin to modulate CSF HIV-1 infection
Probasco JC, Spudich SS, Critchfield J, Lee E, Lollo N, Deeks SG, Price RW. Failure of atorvastatin to modulate CSF HIV-1 infection. Neurology 2008, 71: 521-524. PMID: 18695163, PMCID: PMC2676982, DOI: 10.1212/01.wnl.0000325006.84658.e7.Peer-Reviewed Original ResearchConceptsHIV-1 infectionHIV-1 RNA levelsT-cell countsCell countIntrathecal immunoactivationNeopterin concentrationsBlood lipidsBlood HIV-1 RNA levelCSF HIV-1 RNA levelsCSF white blood cell countCNS HIV-1 infectionSystemic HIV-1 infectionSingle-arm pilot studyWhite blood cell countPilot studyAntiretroviral-naïve subjectsCells/mulRNA levelsUntreated systemic infectionT-lymphocyte countsSmall uncontrolled studiesEffect of atorvastatinHMG-CoA reductase inhibitorsWeeks of treatmentHIV-1 RNA