2021
Colonization with Multidrug-resistant Organisms in Patients with Ventricular Assist Devices
Roberts SC, Nam HH, Kumar RN, Wu T, Harap RS, Pham DT, Rich JD, Stosor V. Colonization with Multidrug-resistant Organisms in Patients with Ventricular Assist Devices. ASAIO Journal 2021, 68: 1048-1053. PMID: 34967790, DOI: 10.1097/mat.0000000000001634.Peer-Reviewed Original ResearchConceptsMultidrug-resistant organismsVentricular assist deviceMDRO colonizationVAD infectionsVAD supportAssist deviceMethicillin-resistant Staphylococcus aureusVancomycin-resistant Enterococcus speciesVAD implantationLeading causeVAD recipientsPatientsInfectionEnterococcus speciesFurther studiesStaphylococcus aureusBest management strategyImplantationRiskNegative bacteriaMorbidityCohortMortalityImpact of colonizationColonization
2020
584. Ventricular assist device infections with Pseudomonas aeruginosa
Roberts S, Nam H, Kumar R, Zembower T, Qi C, Malczynski M, Rich J, Pawale A, Harap R, Stosor V. 584. Ventricular assist device infections with Pseudomonas aeruginosa. Open Forum Infectious Diseases 2020, 7: s356-s356. PMCID: PMC7776381, DOI: 10.1093/ofid/ofaa439.778.Peer-Reviewed Original ResearchDriveline exit siteVAD-specific infectionsVAD infectionsPA infectionVentricular assist device infectionVentricular assist device recipientsPseudomonas aeruginosaSuccessful heart transplantationInfection prevention strategiesNorthwestern Memorial HospitalMultiple antibiotic classesWarrants further studyAntibiotic coursesFQ monotherapyISHLT guidelinesProlonged antibioticsHeart transplantationSurgical debridementVAD implantationCerebrovascular accidentInitial diagnosisMedian timeDevice implantationDevice recipientsAntibiotic treatmentRisk Factors for Fungal Infection in a Ventricular Assist Device Cohort
Roberts S, Rich J, Pham D, Pawale A, Harap R, Wu T, Stosor V. Risk Factors for Fungal Infection in a Ventricular Assist Device Cohort. The Journal Of Heart And Lung Transplantation 2020, 39: s488. DOI: 10.1016/j.healun.2020.01.059.Peer-Reviewed Original ResearchRisk factorsFungal infectionsBacterial infectionsVAD implantationPolymicrobial infectionsVAD devicesVentricular assist device infectionMulti-drug resistant organismsConclusion Risk factorsVAD-related infectionsRetrospective cohort studyIndependent risk factorBinary logistic regression analysisSignificant risk factorsNorthwestern Memorial HospitalLogistic regression analysisHigh mortality rateSPSS Statistics version 25.0Device cohortMDRO infectionVAD infectionsVAD-specificUnderlying diagnosisCohort studyIschemic cardiomyopathy
2019
1177. A Spectrum of Infectious Complications in Continuous-Flow Ventricular Assist Devices: A Single-Center Longitudinal Cohort
Roberts S, Rich J, Pham D, Harap R, Stosor V. 1177. A Spectrum of Infectious Complications in Continuous-Flow Ventricular Assist Devices: A Single-Center Longitudinal Cohort. Open Forum Infectious Diseases 2019, 6: s421-s422. PMCID: PMC6808970, DOI: 10.1093/ofid/ofz360.1040.Peer-Reviewed Original ResearchMultidrug-resistant organismsBlood stream infectionsVentricular assist deviceDriveline exit siteVAD infectionsVAD implantationInfective endocarditisEarly infectionAssist deviceMean timeRetrospective cohort studyMajority of infectionsLongitudinal retrospective cohortType of VADSPSS Statistics version 25.0Flow ventricular assist deviceGram-negativesGP pathogensInfectious complicationsCohort studyFrequent complicationRetrospective cohortNonischemic cardiomyopathyMean ageVAD recipients