2020
520. Longitudinal Analysis of SARS-CoV-2 Viruses in Hospitalized Adults
Simons L, Lorenzo-Redondo R, Nam H, Roberts S, Ison M, Achenbach C, Hauser A, Ozer E, Hultquist J. 520. Longitudinal Analysis of SARS-CoV-2 Viruses in Hospitalized Adults. Open Forum Infectious Diseases 2020, 7: s325-s326. PMCID: PMC7776408, DOI: 10.1093/ofid/ofaa439.714.Peer-Reviewed Original ResearchSARS-CoV-2 viral loadViral loadSARS-CoV-2Hospitalized adultsPositive SARS-CoV-2 testSARS-CoV-2 testWhole viral genome sequencingNasopharyngeal viral loadResults 60 patientsNorthwestern Memorial HospitalCoronavirus disease 2019Viral load dataSARS-CoV-2 virusImmune selective pressureViral genome sequencingQuantitative reverse transcriptase PCRReverse transcriptase-PCRNasopharyngeal specimensNasopharyngeal swabsMemorial HospitalClinical dataIndividual patientsClinical consequencesDisease 2019Immune pressure864. Whole Genome Sequencing is Unable to Track Candida auris Transmission
Roberts S, Ozer E, Zembower T, Qi C. 864. Whole Genome Sequencing is Unable to Track Candida auris Transmission. Open Forum Infectious Diseases 2020, 7: s470-s471. PMCID: PMC7776755, DOI: 10.1093/ofid/ofaa439.1053.Peer-Reviewed Original ResearchNorthwestern Memorial HospitalWhole-genome sequencingC. aurisSingle nucleotide variantsDifferent body sitesMethods Whole-genome sequencingMemorial HospitalResults TwentyPatient isolatesSame patientTransmission clustersPatientsBody sitesPairwise SNP differencesOutbreak investigationHealthcare settingsCandida aurisHospital systemReference labIdentical isolatesAurisFluconazole sensitivityACLEnvironmental specimensCDC516. SARS-CoV-2 Exhibits Clade-specific Differences in Nasopharyngeal Viral Loads
Nam H, Lorenzo-Redondo R, Roberts S, Simons L, Achenbach C, Hauser A, Ison M, Hultquist J, Ozer E. 516. SARS-CoV-2 Exhibits Clade-specific Differences in Nasopharyngeal Viral Loads. Open Forum Infectious Diseases 2020, 7: s324-s324. PMCID: PMC7776718, DOI: 10.1093/ofid/ofaa439.710.Peer-Reviewed Original ResearchNasopharyngeal viral loadViral loadClinical significancePositive SARS-CoV-2 RTSARS-CoV-2 RTCoronavirus disease 2019Further longitudinal studiesNorthwestern Memorial HospitalSARS-CoV-2 isolatesCT valuesSARS-CoV-2SARS-CoV-2 genotypesClade 1 virusesViral cladesClade 2 virusesSymptom onsetClinical parametersNasopharyngeal swabsUpper airwayMemorial HospitalDistinct viral cladesClinical dataDisease 2019Infection with Ureaplasma spp in Lung Transplant Recipients is Donor-Derived
Roberts S, Bharat A, Kurihara C, Ison M. Infection with Ureaplasma spp in Lung Transplant Recipients is Donor-Derived. The Journal Of Heart And Lung Transplantation 2020, 39: s47. DOI: 10.1016/j.healun.2020.01.1220.Peer-Reviewed Original ResearchLung transplant recipientsUreaplasma sppHyperammonemia syndromeTransplant recipientsPositive donorsBronchoalveolar lavageMethods Consecutive patientsNorthwestern Memorial HospitalTime of implantationMicrobial confirmationConsecutive patientsDonor testingConclusions InfectionMemorial HospitalRisk factorsAntimicrobial therapyLTxRsResults SixtyMurine modelNegative testingPatientsActive malesPurpose Recent studiesInfectionHuman subjects
2019
1771. Donor-derived Ureaplasma Infection Increases Mortality in Lung Transplant Recipients
Roberts S, Bharat A, Kurihara C, Bhorade S, Ison M. 1771. Donor-derived Ureaplasma Infection Increases Mortality in Lung Transplant Recipients. Open Forum Infectious Diseases 2019, 6: s653-s653. PMCID: PMC6809047, DOI: 10.1093/ofid/ofz360.1634.Peer-Reviewed Original ResearchDonor-derived infectionTime of LTxLung transplant recipientsHyperammonemia syndromeUreaplasma sppTransplant recipientsDonor screeningPCR testingPre-transplant screeningRetrospective cohort studyRenal replacement therapyBronchoalveolar lavage cultureNegative screening testNorthwestern Memorial HospitalSPSS Statistics version 25.0Donor transmissionEmpiric therapyCohort studyRetrospective cohortDonor testingUrine cultureLavage cultureReplacement therapyMemorial HospitalMental status