2020
Sex differences in left ventricular electrical dyssynchrony and outcomes with cardiac resynchronization therapy
Friedman D, Emerek K, Sørensen P, Zeitler E, Goldstein S, Al-Khatib S, Søgaard P, Graff C, Atwater B. Sex differences in left ventricular electrical dyssynchrony and outcomes with cardiac resynchronization therapy. Heart Rhythm O2 2020, 1: 243-249. PMID: 34113878, PMCID: PMC8183970, DOI: 10.1016/j.hroo.2020.07.004.Peer-Reviewed Original ResearchLeft bundle branch blockCardiac resynchronization therapyElectrical dyssynchronyQRS areaHigher burden of risk factorsLV assist device implantationAssociated with better long-term outcomesQRS characteristicsCardiac resynchronization therapy benefitsBurden of risk factorsCox regression analysisLong-term outcomesBundle branch blockAssist device implantationLV dyssynchronyCardiac transplantationResynchronization therapyBranch blockDevice implantationDyssynchronyFemale sexQRSdRisk factorsElectrophysiological explanationMorphological assessment
2018
Timing of cardiac resynchronization therapy device implantation in heart failure patients and its association with outcomes
Goldstein S, Mentz R, Hellkamp A, Randolph T, Fonarow G, Hernandez A, Yancy C, Al‐Khatib S. Timing of cardiac resynchronization therapy device implantation in heart failure patients and its association with outcomes. Clinical Cardiology 2018, 42: 256-263. PMID: 30548280, PMCID: PMC6386168, DOI: 10.1002/clc.23135.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapy implantationCardiac resynchronization therapyHF re-hospitalizationHeart failureRe-hospitalizationHF hospitalizationCardiac resynchronization therapy device implantationOutcome of all-cause mortalityTime of CRT implantationAssociated with clinical outcomesAssociated with similar benefitsAll-cause mortalityAssociated with lower ratesHeart failure patientsCRT implantationResynchronization therapyClinical outcomesHF patientsDevice implantationFailure patientsCenters for MedicarePatientsDelayed implantationReduce mortalityMedicaid Services data