2000
Dehydroepiandrosterone supplementation augments ovarian stimulation in poor responders: a case series
Casson P, Lindsay M, Pisarska M, Carson S, Buster J. Dehydroepiandrosterone supplementation augments ovarian stimulation in poor responders: a case series. Human Reproduction 2000, 15: 2129-2132. PMID: 11006185, DOI: 10.1093/humrep/15.10.2129.Peer-Reviewed Original ResearchConceptsHuman chorionic gonadotrophinOvarian stimulationDHEA treatmentPoor respondersPoor responseInsulin-like growth factor-1 effectsGrowth hormonePg/Healthy non-smoking womenDay 3 FSHOvarian stimulation responseOvarian stimulation cyclesNon-smoking womenPeak oestradiol concentrationsGonadotrophin doseDehydroepiandrosterone administrationGonadotrophin administrationOvarian responseCase seriesTwin pregnanciesMIU/Intrauterine inseminationOestradiol concentrationsFollicular maturityChorionic gonadotrophin
1997
Effect of postmenopausal estrogen replacement on circulating androgens.
Casson P, Elkind-Hirsch K, Buster J, Hornsby P, Carson S, Snabes M. Effect of postmenopausal estrogen replacement on circulating androgens. Obstetrics And Gynecology 1997, 90: 995-8. PMID: 9397118, DOI: 10.1016/s0029-7844(97)00538-3.Peer-Reviewed Original ResearchConceptsEstrogen replacement therapyMenopausal estrogen replacement therapySerum androgen levelsPostmenopausal womenReplacement therapySex hormonesAndrogen levelsPlacebo-controlled crossover studyAdrenal androgen deficiencyMean serum E2Postmenopausal estrogen replacementEstrogen replacementSerum dehydroepiandrosteroneAndrogen deficiencyBioavailable testosteroneSerum E2Crossover studyTreatment armsAndrogen replacementAdrenal effectsPrevious randomizedPg/Micrograms/TestosteroneSerum samples
1996
Ovarian hyperstimulation augments adrenal dehydroepiandrosterone sulfate secretion**Supported in part by the American College of Obstetricians and Gynecologists-Ortho Academic Training Fellowship, of which Dr. Casson is the 1990-1991 recipient ††Presented in part at the Annual Meetings of the Canadian Fertility and Andrology Society, Quebec, Quebec, Canada, September 11 to 14, 1991; and Kananaskis, alberta, Canada, November 25 to 28, 1992
Casson P, Kristiansen S, Umstot E, Carson S, Buster J. Ovarian hyperstimulation augments adrenal dehydroepiandrosterone sulfate secretion**Supported in part by the American College of Obstetricians and Gynecologists-Ortho Academic Training Fellowship, of which Dr. Casson is the 1990-1991 recipient ††Presented in part at the Annual Meetings of the Canadian Fertility and Andrology Society, Quebec, Quebec, Canada, September 11 to 14, 1991; and Kananaskis, alberta, Canada, November 25 to 28, 1992. Fertility And Sterility 1996, 65: 950-953. PMID: 8612855, DOI: 10.1016/s0015-0282(16)58267-3.Peer-Reviewed Original ResearchConceptsOvarian hyperstimulationHyperstimulation cyclesSerum DHEAStandard ACTH testAdrenal androgen secretionSerum DHEAS levelsOvarian hyperstimulation cyclesProspective clinical studyMain outcome measuresPeak of stimulationDHEAS secretionOvulatory infertilityACTH testInfertile womenF secretionAndrogen secretionCanadian FertilityAndrology SocietyDHEAS levelsInfertility clinicNormal womenE2 levelsIntrapatient variabilityClinical studiesOutcome measures
1991
Superovulation fails to increase human blastocyst yield after uterine lavage
Carson S, Smith A, Scoggan J, Buster J. Superovulation fails to increase human blastocyst yield after uterine lavage. Prenatal Diagnosis 1991, 11: 513-522. PMID: 1766927, DOI: 10.1002/pd.1970110806.Peer-Reviewed Original ResearchConceptsUterine lavageFertile womenHuman chorionic gonadotropin administrationBlastocyst recoveryChorionic gonadotropin administrationBlastocyst yieldGonadotropin administrationOvulation inductionTotal fluid volumeLavage techniqueLavagePreimplantation genetic diagnosisFluid volumeInsemination timingWomenGenetic diagnosisDiagnosisDonor inseminationSuperovulationPreimplantation diagnosisEmbryo collectionDaysInseminationRegimensComplications