2023
Human Uterine Lavage: First Live Births from In Vivo Conceived Genetically Screened Blastocysts
Najmabadi S, Rivas J, Angle M, Nadal A, Bastu E, Munné S, Carson S, Buster J, Nakajima S. Human Uterine Lavage: First Live Births from In Vivo Conceived Genetically Screened Blastocysts. Advances In Therapy 2023, 40: 2534-2541. PMID: 36988819, DOI: 10.1007/s12325-023-02486-1.Peer-Reviewed Original ResearchConceptsFirst live birthEmbryo transfer proceduresLive birthsUterine lavageIntrauterine inseminationEuploid blastocystsOvarian stimulation cyclesObservational case seriesBlastocyst implantation ratePreimplantation genetic testingSets of twinsInfertile womenCase seriesLavage catheterImplantation rateTransfer procedureFertility centerOocyte aspirationStimulation cyclesInfertile couplesLavage procedureSurgical proceduresEmbryo implantationMethodsIn vivoOocyte donors
2005
Comparative genomic hybridization of ectopic pregnancies that fail methotrexate therapy
McKenzie L, El-Zimaity H, Krotz S, Laucirica R, Carson S, Buster J. Comparative genomic hybridization of ectopic pregnancies that fail methotrexate therapy. Fertility And Sterility 2005, 84: 1517-1519. PMID: 16275259, DOI: 10.1016/j.fertnstert.2005.04.064.Peer-Reviewed Original ResearchPrevalence of premature urinary luteinizing hormone surges in women with regular menstrual cycles and its effect on implantation of frozen-thawed embryos
Krotz S, McKenzie L, Cisneros P, Buster J, Amato P, Carson S. Prevalence of premature urinary luteinizing hormone surges in women with regular menstrual cycles and its effect on implantation of frozen-thawed embryos. Fertility And Sterility 2005, 83: 1742-1744. PMID: 15950645, DOI: 10.1016/j.fertnstert.2004.11.078.Peer-Reviewed Original ResearchConceptsPremature LH surgeRegular menstrual cyclesFrozen embryo transferLH surgeEmbryo transferUrinary LHMenstrual cyclePregnancy rateNatural cycle frozen embryo transferFrozen-thawed embryo transferAssisted reproductive technology programRetrospective cohort studyReproductive technology programFrozen-thawed embryosCohort studyPregnancy outcomesMenstruating womenHormone surgePremature LHMAIN OUTCOMEMedical CollegePrivate medical collegeLHWomenRIA kitAlgorithm to predict assisted reproductive technology pregnancy outcome reveals minimal embryo synergy
Torsky S, Amato P, Cisneros P, Sangi-Haghpeykar H, Trukhacheva E, Carson S. Algorithm to predict assisted reproductive technology pregnancy outcome reveals minimal embryo synergy. Fertility And Sterility 2005, 83: 782-784. PMID: 15749519, DOI: 10.1016/j.fertnstert.2004.10.028.Peer-Reviewed Original ResearchPreimplantation Genetic Diagnosis (PGD) for Heritable Neoplasia
Simpson J, Carson S, Cisneros P. Preimplantation Genetic Diagnosis (PGD) for Heritable Neoplasia. JNCI Monographs 2005, 2005: 87-90. PMID: 15784832, DOI: 10.1093/jncimonographs/lgi027.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiopsyBlastocystBlastomeresCord Blood Stem Cell TransplantationEmbryo TransferFemaleGenetic CounselingGenetic Diseases, InbornGenetic Predisposition to DiseaseGenotypeHLA AntigensHumansInfant, NewbornMaleNeoplasmsPregnancyPregnancy OutcomePreimplantation DiagnosisTruth DisclosureWillsConceptsAdenomatous polyposis coliPreimplantation genetic diagnosisMolecular basisGenetic diagnosisMendelian disordersMendelian formsPolyposis coliEmbryosVon Hippel-Lindau syndromeMore cellsLi-Fraumeni syndromeGametesGenesPolar body biopsyDNADays postconceptionColiTransfer of embryosBlastocystsTrophectoderm biopsyStem cell implantationBRCA1Specific HLA genotypesGenotypesCells
2004
Human cumulus granulosa cell gene expression: a predictor of fertilization and embryo selection in women undergoing IVF
McKenzie L, Pangas S, Carson S, Kovanci E, Cisneros P, Buster J, Amato P, Matzuk M. Human cumulus granulosa cell gene expression: a predictor of fertilization and embryo selection in women undergoing IVF. Human Reproduction 2004, 19: 2869-2874. PMID: 15471935, DOI: 10.1093/humrep/deh535.Peer-Reviewed Original ResearchAdultC-Reactive ProteinCyclooxygenase 2Embryo, MammalianFemaleFertilization in VitroGene ExpressionGlucuronosyltransferaseGranulosa CellsHumansHyaluronan SynthasesIntercellular Signaling Peptides and ProteinsMembrane ProteinsPredictive Value of TestsPregnancyPregnancy RateProstaglandin-Endoperoxide SynthasesROC CurveSerum Amyloid P-ComponentCharacterizing ectopic pregnancies that rupture despite treatment with methotrexate
Dudley P, Heard M, Sangi-Haghpeykar H, Carson S, Buster J. Characterizing ectopic pregnancies that rupture despite treatment with methotrexate. Fertility And Sterility 2004, 82: 1374-1378. PMID: 15533363, DOI: 10.1016/j.fertnstert.2004.03.066.Peer-Reviewed Original ResearchConceptsTubal ruptureEctopic pregnancyRisk factorsHCG valuesHuman chorionic gonadotropin valuesRetrospective case-control analysisIndependent risk factorUrban medical centerCase-control analysisConcentrations of hCGEctopic gestationMTX administrationIndependent predictorsSurgical interventionGonadotropin valuesHCG concentrationsMAIN OUTCOMEMedical CenterMethotrexateImplantation sitesPregnancyTubal isthmusPatientsPredictive variablesTreatmentPregnancy outcome of in vitro fertilization/intracytoplasmic sperm injection with profound teratospermia
McKenzie L, Kovanci E, Amato P, Cisneros P, Lamb D, Carson S. Pregnancy outcome of in vitro fertilization/intracytoplasmic sperm injection with profound teratospermia. Fertility And Sterility 2004, 82: 847-849. PMID: 15482758, DOI: 10.1016/j.fertnstert.2004.03.054.Peer-Reviewed Original ResearchConceptsIntracytoplasmic sperm injectionIVF/intracytoplasmic sperm injectionPregnancy outcomesSperm injectionFertilization/intracytoplasmic sperm injectionIVF/ICSI cyclesTertiary care centerAppropriate developmental milestonesBirth defectsStrict criteriaTime of deliveryKruger's strict criteriaYears of ageAcceptable pregnancy ratesOvarian stimulationICSI cyclesIncreased riskCare centerPregnancy rateRetrospective analysisMAIN OUTCOMETransvaginal aspirationEmbryo transferInfant statusSmall seriesNuclear chromosomal localization in human preimplantation embryos: correlation with aneuploidy and embryo morphology
McKenzie L, Carson S, Marcelli S, Rooney E, Cisneros P, Torskey S, Buster J, Simpson J, Bischoff F. Nuclear chromosomal localization in human preimplantation embryos: correlation with aneuploidy and embryo morphology. Human Reproduction 2004, 19: 2231-2237. PMID: 15298970, DOI: 10.1093/humrep/deh391.Peer-Reviewed Original ResearchConceptsChromosome 13Aneuploid blastomeresOrganization of chromosomesLocalization of chromosomesRegulatory protein functionHuman preimplantation embryosChromosome localizationChromosomal localizationProtein functionTranscriptional activityPreimplantation embryosChromosomesStage embryosEmbryo morphologyNormal blastomeresBlastomeresEmbryosHuman blastomeresSitu hybridizationSpatial organizationAbnormal embryosPreimplantation genetic diagnosisLocalizationGenetic diagnosis
2003
Preimplantation genetic diagnosis for a known cryptic translocation: Follow‐up clinical report and implication of segregation products
McKenzie L, Cisneros P, Torsky S, Bacino C, Buster J, Carson S, Simpson J, Bischoff F. Preimplantation genetic diagnosis for a known cryptic translocation: Follow‐up clinical report and implication of segregation products. American Journal Of Medical Genetics Part A 2003, 121A: 56-59. PMID: 12900903, DOI: 10.1002/ajmg.a.20159.Peer-Reviewed Original ResearchConceptsPreimplantation genetic diagnosisCryptic translocationMaternal age-related aneuploidyAge-related aneuploidyGenetic diagnosisChromosome 17 centromere probeSevere mental retardationChorionic villus samplingUnbalanced productsPregnancy terminationClinical reportsEmpiric riskVillus samplingTransferable embryosMental retardationFrequent modeNormal offspringDiagnosisChildrenReportTranslocationUnbalanced segregants
2002
Pregnancies following use of metformin for ovulation induction in patients with polycystic ovary syndrome
Heard M, Pierce A, Carson S, Buster J. Pregnancies following use of metformin for ovulation induction in patients with polycystic ovary syndrome. Fertility And Sterility 2002, 77: 669-673. PMID: 11937113, DOI: 10.1016/s0015-0282(01)03266-6.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeOvary syndromeSpontaneous abortionDiagnosis of PCOSAnovulatory infertility patientsUse of metforminResumption of mensesGastrointestinal-related side effectsEvidence of ovulationDosage of metforminAnovulatory patientsMetformin therapyPCOS resultsClomiphene citrateOvulation inductionPregnancy outcomesSpontaneous mensesInfertility patientsCase seriesMedian timeOvulatory responseMAIN OUTCOMESide effectsPatientsMetformin
2001
Multiple pregnancies: action is taking place
Soules M, Chang R, Lipshultz L, Keye W, Carson S. Multiple pregnancies: action is taking place. Fertility And Sterility 2001, 75: 15-16. PMID: 11163809, DOI: 10.1016/s0015-0282(00)01726-x.Commentaries, Editorials and Letters
2000
Dehydroepiandrosterone supplementation augments ovarian stimulation in poor responders: a case series
Casson P, Lindsay M, Pisarska M, Carson S, Buster J. Dehydroepiandrosterone supplementation augments ovarian stimulation in poor responders: a case series. Human Reproduction 2000, 15: 2129-2132. PMID: 11006185, DOI: 10.1093/humrep/15.10.2129.Peer-Reviewed Original ResearchConceptsHuman chorionic gonadotrophinOvarian stimulationDHEA treatmentPoor respondersPoor responseInsulin-like growth factor-1 effectsGrowth hormonePg/Healthy non-smoking womenDay 3 FSHOvarian stimulation responseOvarian stimulation cyclesNon-smoking womenPeak oestradiol concentrationsGonadotrophin doseDehydroepiandrosterone administrationGonadotrophin administrationOvarian responseCase seriesTwin pregnanciesMIU/Intrauterine inseminationOestradiol concentrationsFollicular maturityChorionic gonadotrophin
1999
Fertilization after standard in vitro fertilization versus intracytoplasmic sperm injection in subfertile males using sibling oocytes
Pisarska M, Casson P, Cisneros P, Lamb D, Lipshultz L, Buster J, Carson S. Fertilization after standard in vitro fertilization versus intracytoplasmic sperm injection in subfertile males using sibling oocytes. Fertility And Sterility 1999, 71: 627-632. PMID: 10202870, DOI: 10.1016/s0015-0282(98)00538-x.Peer-Reviewed Original ResearchConceptsSevere teratozoospermiaEmbryo qualityConventional IVFGroup AMale populationMean percentIntracytoplasmic sperm injectionProspective experimental studyFertilization rateIVF cyclesICSI cyclesOvulation inductionGroup BICSI resultsMore abnormalitiesMAIN OUTCOMESperm injectionIVFICSIIVF clinicsSubfertile malesHigher fertilization rateRandom allocationTeratozoospermiaSignificant differencesIncidence and risk factors for ectopic pregnancy.
Pisarska M, Carson S. Incidence and risk factors for ectopic pregnancy. Clinical Obstetrics & Gynecology 1999, 42: 2-8; quiz 55-6. PMID: 10073294, DOI: 10.1097/00003081-199903000-00004.Peer-Reviewed Original ResearchIndividual growth patterns in the first trimester: evidence for difference in embryonic and fetal growth rates
Deter R, Buster J, Casson P, Carson S. Individual growth patterns in the first trimester: evidence for difference in embryonic and fetal growth rates. Ultrasound In Obstetrics And Gynecology 1999, 13: 90-98. PMID: 10079486, DOI: 10.1046/j.1469-0705.1999.13020090.x.Peer-Reviewed Original ResearchConceptsCrown-rump lengthMenstrual ageFirst trimesterFetal lengthIndividual fetusesFirst trimester growthGroups of fetusesFetal growth rateWeeks' menstrual ageMaximum axial lengthIVF groupFetal growthFetal problemsSpontaneous fertilizationFetusesAxial lengthSimilar findingsGrowth abnormalitiesWeeksWeekly intervalsAgeTrimesterPatientsStraight line lengthAccurate assessmentEfficacy of Superovulation and Intrauterine Insemination in the Treatment of Infertility
Guzick D, Carson S, Coutifaris C, Overstreet J, Factor-Litvak P, Steinkampf M, Hill J, Mastroianni L, Buster J, Nakajima S, Vogel D, Canfield R. Efficacy of Superovulation and Intrauterine Insemination in the Treatment of Infertility. New England Journal Of Medicine 1999, 340: 177-183. PMID: 9895397, DOI: 10.1056/nejm199901213400302.Peer-Reviewed Original ResearchConceptsIntrauterine insemination groupIntrauterine inseminationInduction of superovulationIntracervical inseminationCox proportional hazards analysisProportional hazards analysisTreatment of infertilityInfertility factorsClinical trialsInfertile couplesEfficacy of superovulationPregnancySuperovulationTreatmentInfertilityHigh rateMotile spermInseminationGroupInductionGonadotropinTrialsWomen
1998
Heterotopic abdominal pregnancy treated at laparoscopy
Pisarska M, Casson P, Moise K, DiMaio D, Buster J, Carson S. Heterotopic abdominal pregnancy treated at laparoscopy. Fertility And Sterility 1998, 70: 159-160. PMID: 9660440, DOI: 10.1016/s0015-0282(98)00104-6.Peer-Reviewed Original ResearchConceptsHeterotopic abdominal pregnancyAbdominal pregnancyIVF-ETConcurrent intrauterine pregnancyIntrauterine pregnancyLaparoscopic treatmentHuman chorionic gonadotropin levelsEctopic abdominal pregnancyPrimary abdominal pregnancyPelvic ultrasound examinationChorionic gonadotropin levelsSuccessful laparoscopic treatmentAbdominal gestationLuteal supportIntrauterine gestationOvulation inductionGonadotropin levelsPathologic findingsIVF programCase reportUltrasound examinationEarly diagnosisMAIN OUTCOMEPregnancyLaparoscopyLack of Association Between Antiphospholipid Antibodies and First-Trimester Spontaneous Abortion: Prospective Study of Pregnancies Detected Within 21 Days of Conception 11Supported by grants and contracts from the National Institute of Child Health and Human Development, National Institutes of Health.
Simpson J, Carson S, Chesney C, Conley M, Metzger B, Aarons J, Holmes L, Jovanovic-Peterson L, Knopp R, Mills J. Lack of Association Between Antiphospholipid Antibodies and First-Trimester Spontaneous Abortion: Prospective Study of Pregnancies Detected Within 21 Days of Conception 11Supported by grants and contracts from the National Institute of Child Health and Human Development, National Institutes of Health. Fertility And Sterility 1998, 69: 814-820. PMID: 9591485, DOI: 10.1016/s0015-0282(98)00054-5.Peer-Reviewed Original ResearchConceptsAntiphospholipid antibodiesAnticardiolipin antibodiesPregnancy lossProspective studyFirst trimester pregnancy lossEnzyme immunoassayFirst-trimester spontaneous abortionsFirst trimester lossNational InstituteLack of associationDay of conceptionFetal deathRetrospective studySpontaneous abortionLive birthsMAIN OUTCOMEChild healthSuch antibodiesBlood samplesPregnancyMulticenter universityAntibodiesSerumWomenSelection biasEctopic pregnancy
Pisarska M, Carson S, Buster J. Ectopic pregnancy. The Lancet 1998, 351: 1115-1120. PMID: 9660597, DOI: 10.1016/s0140-6736(97)11476-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements