2022
Therapeutic US Applications for the Abdomen and Pelvis.
Sailer A, Ghanouni P, Schade G, Napoli A, Vidal-Jove J, Raman S, Mendiratta-Lala M, Ghai S, Abreu A, Sundaram K, Westphalen A, Arora S. Therapeutic US Applications for the Abdomen and Pelvis. RadioGraphics 2022, 42: e182-e183. PMID: 36190852, PMCID: PMC9539095, DOI: 10.1148/rg.220044.Peer-Reviewed Original ResearchRadiologists staunchly support patient safety and autonomy, in opposition to the SCOTUS decision to overturn Roe v Wade
Karandikar A, Solberg A, Fung A, Lee AY, Farooq A, Taylor AC, Oliveira A, Narayan A, Senter A, Majid A, Tong A, McGrath AL, Malik A, Brown AL, Roberts A, Fleischer A, Vettiyil B, Zigmund B, Park B, Curran B, Henry C, Jaimes C, Connolly C, Robson C, Meltzer CC, Phillips CH, Dove C, Glastonbury C, Pomeranz C, Kirsch CFE, Burgan CM, Scher C, Tomblinson C, Fuss C, Santillan C, Daye D, Brown DB, Young DJ, Kopans D, Vargas D, Martin D, Thompson D, Jordan DW, Shatzkes D, Sun D, Mastrodicasa D, Smith E, Korngold E, Dibble EH, Arleo EK, Hecht EM, Morris E, Maltin EP, Cooke EA, Schwartz ES, Lehrman E, Sodagari F, Shah F, Doo FX, Rigiroli F, Vilanilam GK, Landinez G, Kim GG, Rahbar H, Choi H, Bandesha H, Ojeda-Fournier H, Ikuta I, Dragojevic I, Schroeder JLT, Ivanidze J, Katzen JT, Chiang J, Nguyen J, Robinson JD, Broder JC, Kemp J, Weaver JS, Conyers JM, Robbins JB, Leschied JR, Wen J, Park J, Mongan J, Perchik J, Barbero JPM, Jacob J, Ledbetter K, Macura KJ, Maturen KE, Frederick-Dyer K, Dodelzon K, Cort K, Kisling K, Babagbemi K, McGill KC, Chang KJ, Feigin K, Winsor KS, Seifert K, Patel K, Porter KK, Foley KM, Patel-Lippmann K, McIntosh LJ, Padilla L, Groner L, Harry LM, Ladd LM, Wang L, Spalluto LB, Mahesh M, Marx MV, Sugi MD, Sammer MBK, Sun M, Barkovich MJ, Miller MJ, Vella M, Davis MA, Englander MJ, Durst M, Oumano M, Wood MJ, McBee MP, Fischbein NJ, Kovalchuk N, Lall N, Eclov N, Madhuripan N, Ariaratnam NS, Vincoff NS, Kothary N, Yahyavi-Firouz-Abadi N, Brook OR, Glenn OA, Woodard PK, Mazaheri P, Rhyner P, Eby PR, Raghu P, Gerson RF, Patel R, Gutierrez RL, Gebhard R, Andreotti RF, Masum R, Woods R, Mandava S, Harrington SG, Parikh S, Chu S, Arora SS, Meyers SM, Prabhu S, Shams S, Pittman S, Patel SN, Payne S, Hetts SW, Hijaz TA, Chapman T, Loehfelm TW, Juang T, Clark TJ, Potigailo V, Shah V, Planz V, Kalia V, DeMartini W, Dillon WP, Gupta Y, Koethe Y, Hartley-Blossom Z, Wang ZJ, McGinty G, Haramati A, Allen LM, Germaine P. Radiologists staunchly support patient safety and autonomy, in opposition to the SCOTUS decision to overturn Roe v Wade. Clinical Imaging 2022, 93: 117-121. PMID: 36064645, DOI: 10.1016/j.clinimag.2022.07.011.Peer-Reviewed Original Research
2021
Imaging Features at the Periphery: Hemodynamics, Pathophysiology, and Effect on LI-RADS Categorization.
Consul N, Sirlin CB, Chernyak V, Fetzer DT, Masch WR, Arora SS, Do RKG, Marks RM, Fowler KJ, Borhani AA, Elsayes KM. Imaging Features at the Periphery: Hemodynamics, Pathophysiology, and Effect on LI-RADS Categorization. RadioGraphics 2021, 41: 1657-1675. PMID: 34559586, DOI: 10.1148/rg.2021210019.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaEnhancement patternLiver observationsCapsule appearanceRim arterial phase hyperenhancementAncillary featuresNon-HCC malignanciesLocal-regional therapyArterial phase hyperenhancementLiver Imaging ReportingDynamic contrast-enhanced imagingDifferent enhancement patternsImaging-based diagnosisContrast-enhanced imagingPeripheral washoutArterioportal shuntTargetoid appearanceNodular enhancementCorona enhancementBenign entityTreatment responseLI-RADSRisk populationsLiver lesionsSpecific diagnosisHCC: role of pre- and post-treatment tumor biology in driving adverse outcomes and rare responses to therapy
Arora S, Catania R, Borhani A, Horvat N, Fowler K, Harmath C. HCC: role of pre- and post-treatment tumor biology in driving adverse outcomes and rare responses to therapy. Abdominal Radiology 2021, 46: 3686-3697. PMID: 34195886, DOI: 10.1007/s00261-021-03192-8.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaTumor biologyHCC tumor biologyRare responsesTreatment hepatocellular carcinomaPost-treatment responsePrognostic featuresAbscopal effectAdverse outcomesCancer deathIdeal therapyEffective therapyImaging featuresDisease evolveIndividual patientsLiver cancerMore therapiesTumor behaviorTreatment planParticular tumorTherapyClinical useTreatment planningPatientsTumorsLI-RADS treatment response lexicon: review, refresh and resolve with emerging data
Ram R, Kampalath R, Shenoy-Bhangle AS, Arora S, Kielar AZ, Mendiratta-Lala M. LI-RADS treatment response lexicon: review, refresh and resolve with emerging data. Abdominal Radiology 2021, 46: 3549-3557. PMID: 34106301, DOI: 10.1007/s00261-021-03149-x.Peer-Reviewed Original ResearchConceptsTreatment response algorithmHepatocellular carcinomaRegional treatmentData System treatment response algorithmLI-RADS treatment response algorithmLoco-regional therapyLoco-regional treatmentLiver Imaging ReportingTreatment response assessmentCross-sectional modalitiesType of treatmentRegional therapyCurrent guidelinesTreatment responseResponse assessmentImaging ReportingCarcinomaTreatmentHepatocellular carcinoma: metastatic pathways and extra-hepatic findings
Arora S, Harmath C, Catania R, Mandler A, Fowler KJ, Borhani AA. Hepatocellular carcinoma: metastatic pathways and extra-hepatic findings. Abdominal Radiology 2021, 46: 3698-3707. PMID: 34091729, DOI: 10.1007/s00261-021-03151-3.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaExtrahepatic diseaseMetastatic diseaseManagement of patientsEarly metastatic diseaseCourse of treatmentExtrahepatic spreadDefinitive treatmentInitial presentationTreatment optionsPrecise stagingMetastatic pathwaysTumor biologySystemic spreadMolecular derangementsPatientsDiseasePotential roleDifferent pathwaysMolecular characteristicsTreatmentPathwayCarcinomaDerangementStagingRole of the radiologist at HCC multidisciplinary conference and use of the LR-TR algorithm for improving workflow
Shenoy-Bhangle AS, Tsai LL, Masciocchi M, Arora SS, Kielar AZ. Role of the radiologist at HCC multidisciplinary conference and use of the LR-TR algorithm for improving workflow. Abdominal Radiology 2021, 46: 3558-3564. PMID: 33904990, DOI: 10.1007/s00261-021-03094-9.Peer-Reviewed Original ResearchConceptsLiver-directed locoregional therapiesLR-TR algorithmHepatocellular carcinomaLocoregional therapyMultidisciplinary conferenceLiver observationsTreatment of HCCLiver-directed therapiesLiver Imaging ReportingOptimal patient managementPost-treatment imagingRadiologic findingsLiver diseaseOncology patientsTransplant eligibilityInterdisciplinary managementHCC screeningPatient managementMultidisciplinary discussionPatient careImaging ReportingPatientsTherapyRadiologistsDiseaseThe impact and collateral damage of COVID-19 on prostate MRI and guided biopsy operations: Society of Abdominal Radiology Prostate Cancer Disease-Focused Panel survey analysis
Surasi DSS, Wang X, Bathala TK, Hwang H, Arora S, Westphalen AC, Chang SD, Turkbey B. The impact and collateral damage of COVID-19 on prostate MRI and guided biopsy operations: Society of Abdominal Radiology Prostate Cancer Disease-Focused Panel survey analysis. Abdominal Radiology 2021, 46: 4362-4369. PMID: 33904992, PMCID: PMC8077193, DOI: 10.1007/s00261-021-03087-8.Peer-Reviewed Original ResearchConceptsBowel preparationMedian numberProstate MRICoronavirus disease 2019 (COVID-19) pandemicCOVID-19Disease 2019 pandemicCOVID-19 pandemicHealth care systemComplete responseMedical oncologyProstate biopsyClinic schedulesProstate cancerMRI studiesLockdown periodCare systemCollateral damageRadiation oncologyClinical departmentsPanel survey analysisMRIBiopsyRadiology departmentOncologyDescriptive statisticsDiagnostic renal mass biopsy is associated with individual categories of PADUA and RENAL nephrometry scores: Analysis of diagnostic and concordance rates with surgical resection
Fonseca RB, Straub Hogan MM, Kapp ME, Cate F, Coogan A, Arora S, Gordetsky J, Smelser WW, Clark PE, Cates J, Giannico GA. Diagnostic renal mass biopsy is associated with individual categories of PADUA and RENAL nephrometry scores: Analysis of diagnostic and concordance rates with surgical resection. Urologic Oncology Seminars And Original Investigations 2021, 39: 371.e7-371.e15. PMID: 33773915, PMCID: PMC8205938, DOI: 10.1016/j.urolonc.2021.02.022.Peer-Reviewed Original ResearchConceptsCore needle biopsySmall renal massesFine-needle aspirationRenal mass biopsyDiagnostic core needle biopsyDiagnostic fine needle aspirationRenal massesNon-diagnostic rateCystic massMass biopsyConcordance rateEndophytic growthRenal sinus invasionRENAL nephrometry scoreSurgical resection specimensSurgical resectionNephrometry scoreSinus invasionRetrospective studyPreoperative aspectsResection specimensSingle institutionClinical managementSubset analysisNeedle biopsyMR-Guided High-Intensity Directional Ultrasound Ablation of Prostate Cancer
Galgano SJ, Planz VB, Arora S, Rais-Bahrami S. MR-Guided High-Intensity Directional Ultrasound Ablation of Prostate Cancer. Current Urology Reports 2021, 22: 3. PMID: 33403460, DOI: 10.1007/s11934-020-01020-y.Peer-Reviewed Original ResearchConceptsTreatment modalitiesProstate cancerFocal therapyFavorable side effect profileLong-term oncologic outcomesSide effect profileMR-Guided HighNovel treatment modalitiesPromising early resultsProstate cancer diagnosisOncologic outcomesDefinitive treatmentUrinary sphincterNeurovascular bundleRadical prostatectomyActive surveillanceRadiation therapyFocal ablationHeterogeneous diseaseProstate glandReviewThe goalTherapyUltrasound ablationCancer diagnosisProstate MRI
2020
Magnetic Resonance Imaging-Guided Transurethral Ultrasound Ablation of Prostate Cancer.
Klotz L, Pavlovich CP, Chin J, Hatiboglu G, Koch M, Penson D, Raman S, Oto A, Fütterer J, Serrallach M, Relle J, Lotan Y, Heidenreich A, Bonekamp D, Haider M, Tirkes T, Arora S, Macura KJ, Costa DN, Persigehl T, Pantuck AJ, Bomers J, Burtnyk M, Staruch R, Eggener S. Magnetic Resonance Imaging-Guided Transurethral Ultrasound Ablation of Prostate Cancer. Journal Of Urology 2020, 205: 769-779. PMID: 33021440, DOI: 10.1097/ju.0000000000001362.Peer-Reviewed Original ResearchConceptsGrade Group 2 diseaseProstate-specific antigen reductionGrade group 2Whole gland ablationTransurethral ultrasound ablationAntigen reductionMagnetic resonance imagingProstate cancerGroup 2Gland ablationMagnetic resonance imaging-guided transurethral ultrasound ablationGrade 3 adverse eventsResonance imagingTarget volumeEvidence of cancerUltrasound ablationIntermediate-risk diseaseRisk prostate cancerProspective multicenter trialMedian prostate volumeLocalized prostate cancerMedian treatment delivery timeTreatment delivery timeMagnetic resonancePrimary endpointQuality Comparison of 3 Tesla multiparametric MRI of the prostate using a flexible surface receiver coil versus conventional surface coil plus endorectal coil setup
Ullrich T, Kohli M, Ohliger M, Magudia K, Arora S, Barrett T, Bittencourt L, Margolis D, Schimmöller L, Turkbey B, Westphalen A. Quality Comparison of 3 Tesla multiparametric MRI of the prostate using a flexible surface receiver coil versus conventional surface coil plus endorectal coil setup. Abdominal Radiology 2020, 45: 4260-4270. PMID: 32696213, PMCID: PMC7716937, DOI: 10.1007/s00261-020-02641-0.Peer-Reviewed Original ResearchVariability of the Positive Predictive Value of PI-RADS for Prostate MRI across 26 Centers: Experience of the Society of Abdominal Radiology Prostate Cancer Disease-focused Panel
Westphalen AC, McCulloch CE, Anaokar JM, Arora S, Barashi NS, Barentsz JO, Bathala TK, Bittencourt LK, Booker MT, Braxton VG, Carroll PR, Casalino DD, Chang SD, Coakley FV, Dhatt R, Eberhardt SC, Foster BR, Froemming AT, Fütterer JJ, Ganeshan DM, Gertner MR, Mankowski Gettle L, Ghai S, Gupta RT, Hahn ME, Houshyar R, Kim C, Kim CK, Lall C, Margolis DJA, McRae SE, Oto A, Parsons RB, Patel NU, Pinto PA, Polascik TJ, Spilseth B, Starcevich JB, Tammisetti VS, Taneja SS, Turkbey B, Verma S, Ward JF, Warlick CA, Weinberger AR, Yu J, Zagoria RJ, Rosenkrantz AB. Variability of the Positive Predictive Value of PI-RADS for Prostate MRI across 26 Centers: Experience of the Society of Abdominal Radiology Prostate Cancer Disease-focused Panel. Radiology 2020, 296: 76-84. PMID: 32315265, PMCID: PMC7373346, DOI: 10.1148/radiol.2020190646.Peer-Reviewed Original ResearchConceptsPositive predictive valuePI-RADS scoreProstate cancerPI-RADSGleason scorePredictive valueRetrospective cross-sectional studyHigh-grade prostate cancerObserved positive predictive valueOverall positive predictive valueUntreated prostate cancerProstate MRIInterquartile rangeSignificant prostate cancerProstate Imaging ReportingCross-sectional studyMixed-model logistic regressionProstate cancer diseaseReporting Data SystemMRI lesionsBiopsy resultsActive surveillanceClinical careMRI scansImaging ReportingMagnetic Resonance Imaging-Guided Transurethral Ultrasound Ablation of Localized Prostate Cancer: Preliminary Experience from a Single Center in a Prospective, Multi-Center, Single-Arm Clinical Trial
Sundaram KM, Staruch R, Burtnyk M, Lane JS, Penson DF, Arora SS. Magnetic Resonance Imaging-Guided Transurethral Ultrasound Ablation of Localized Prostate Cancer: Preliminary Experience from a Single Center in a Prospective, Multi-Center, Single-Arm Clinical Trial. Journal Of Vascular And Interventional Radiology 2020, 31: 740-746.e4. PMID: 32307311, DOI: 10.1016/j.jvir.2019.12.802.Peer-Reviewed Original ResearchMeSH KeywordsAblation TechniquesAgedAged, 80 and overHumansMagnetic Resonance Imaging, InterventionalMaleMiddle AgedNeoplasm GradingNeoplasm StagingOntarioPreliminary DataProspective StudiesProstatic NeoplasmsTime FactorsTransurethral Resection of ProstateTreatment OutcomeUltrasonic Surgical ProceduresConceptsTransurethral ultrasound ablationProstate cancerMagnetic resonance imaging-guided transurethral ultrasound ablationIntermediate-risk prostate cancerUltrasound ablationIntermediate-risk diseaseSingle-center experienceGastrointestinal side effectsLocalized prostate cancerArm clinical trialMagnetic resonance imagingHistologic benefitPostprocedural changesPrimary endpointSingle centerClinical trialsMulti-CenterSide effectsPreliminary experienceResonance imagingPatientsProstate treatmentCancerAblationBiopsy
2019
MRI of the Male Pelvic Floor.
Lakhoo J, Khatri G, Elsayed RF, Chernyak V, Olpin J, Steiner A, Tammisetti VS, Sundaram KM, Arora SS. MRI of the Male Pelvic Floor. RadioGraphics 2019, 39: 2003-2022. PMID: 31697623, DOI: 10.1148/rg.2019190064.Peer-Reviewed Original ResearchConceptsPelvic floorSexual dysfunctionDynamic MRI featuresPelvic floor disordersMale pelvic floorPelvic floor anatomyPelvic floor structuresIncreased toneFemale pelvic floorAnal sphincterChronic painTreatment failureGastrointestinal disordersAnorectal disordersMRI featuresMR defecographyPelvic organsSex-specific differencesPathophysiologic disordersOnline supplemental materialPelvic musculaturePostsurgical functionDysfunctionFemale pelvisMRI techniquesAn update for LI‐RADS: Version 2018. Why so soon after version 2017?
Kielar AZ, Chernyak V, Bashir MR, K. R, Fowler KJ, Santillan C, Sirlin CB, Mitchell DG, Cerny M, Tang A, Elsayes KM, Kamaya A, Kono Y, Arora SS. An update for LI‐RADS: Version 2018. Why so soon after version 2017? Journal Of Magnetic Resonance Imaging 2019, 50: 1990-1991. PMID: 30864185, DOI: 10.1002/jmri.26715.Peer-Reviewed Original Research
2018
White paper of the Society of Abdominal Radiology hepatocellular carcinoma diagnosis disease-focused panel on LI-RADS v2018 for CT and MRI
Elsayes KM, Kielar AZ, Elmohr MM, Chernyak V, Masch WR, Furlan A, Marks RM, Cruite I, Fowler KJ, Tang A, Bashir MR, Hecht EM, Kamaya A, Jambhekar K, Kamath A, Arora S, Bijan B, Ash R, Kassam Z, Chaudhry H, McGahan JP, Yacoub JH, McInnes M, Fung AW, Shanbhogue K, Lee J, Deshmukh S, Horvat N, Mitchell DG, Do RKG, Surabhi VR, Szklaruk J, Sirlin CB. White paper of the Society of Abdominal Radiology hepatocellular carcinoma diagnosis disease-focused panel on LI-RADS v2018 for CT and MRI. Abdominal Radiology 2018, 43: 2625-2642. PMID: 30155697, DOI: 10.1007/s00261-018-1744-4.Peer-Reviewed Original ResearchConceptsLI-RADS v2018Hepatocellular carcinomaClinical practice guidanceDiagnostic imaging criteriaImaging-based diagnosisReporting Data SystemSurveillance ultrasoundLiver diseaseImaging criteriaArterial phaseLI-RADSClinical careOrgan procurementLiver imagingDiagnostic algorithmV2018American AssociationPractice guidanceThreshold growthNetwork definitionAASLDPatientsCarcinomaData System
2016
Magnetic resonance-ultrasound fusion prostate biopsy in the diagnosis of prostate cancer
Tyson MD, Arora SS, Scarpato KR, Barocas D. Magnetic resonance-ultrasound fusion prostate biopsy in the diagnosis of prostate cancer. Urologic Oncology Seminars And Original Investigations 2016, 34: 326-332. PMID: 27083114, PMCID: PMC4912896, DOI: 10.1016/j.urolonc.2016.03.005.Peer-Reviewed Original ResearchConceptsMultiparametric magnetic resonance imagingMR-US fusionProstate cancerMR-US fusion biopsyLow-risk cancersFusion prostate biopsyProstate needle biopsyBore MRI-guided biopsyMRI-guided biopsyMagnetic resonance imagingInsignificant diseaseFusion biopsyProstate biopsyNeedle biopsySuspicious lesionsTransrectal ultrasoundBiopsyBiopsy techniqueResonance imagingCancerDirect targetingRelevant diseasesProstateDiseaseDiagnosisDifficult biopsy and drainage: just say yes
Frederick-Dyer K, Ahmad A, Arora SS, Wile G. Difficult biopsy and drainage: just say yes. Abdominal Radiology 2016, 41: 706-719. PMID: 26916352, DOI: 10.1007/s00261-016-0666-2.Peer-Reviewed Original Research
2009
Atherosclerotic Plaque Progression in Carotid Arteries: Monitoring with High-Spatial-Resolution MR Imaging—Multicenter Trial
Boussel L, Arora S, Rapp J, Rutt B, Huston J, Parker D, Yuan C, Bassiouny H, Saloner D, Investigators F. Atherosclerotic Plaque Progression in Carotid Arteries: Monitoring with High-Spatial-Resolution MR Imaging—Multicenter Trial. Radiology 2009, 252: 789-96. PMID: 19508991, PMCID: PMC2734890, DOI: 10.1148/radiol.2523081798.Peer-Reviewed Original ResearchConceptsStatin therapyCarotid arteryVessel wall volumeInstitutional review boardMR imagingRate of progressionAtherosclerotic plaque progressionUnenhanced T1-weighted imagesSite's institutional review boardMagnetic resonance imagingT1-weighted imagesU.S. study sitesMean annual changeAtheroma volumeClinical factorsMulticenter trialCarotid diseaseFraction of studiesMulticenter studyPlaque progressionMultiple linear regression analysisLow bifurcationPatientsArteryLinear regression analysis