2014
Confounding by indication affects antimicrobial risk factors for methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition
Datta R, Kleinman K, Rifas-Shiman S, Placzek H, Lankiewicz J, Platt R, Huang SS, for the CDC Prevention Epicenters. Confounding by indication affects antimicrobial risk factors for methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition. Antimicrobial Resistance & Infection Control 2014, 3: 19. PMID: 24932407, PMCID: PMC4057914, DOI: 10.1186/2047-2994-3-19.Peer-Reviewed Original ResearchMethicillin-resistant Staphylococcus aureusVancomycin-resistant enterococci acquisitionEmpiric antibioticsRisk factorsVRE acquisitionAntibiotic prescriptionsMRSA acquisitionScreening culturesIntensive care unit patientsAntibiotic utilization dataMRSA-positive patientsVRE-positive patientsCare unit patientsMedical record reviewDiagnosis of infectionEvidence of treatmentSymptoms of infectionStaphylococcus aureusBackgroundObservational studiesEmpiric therapyUnit patientsRecord reviewTreatment indicationsPrior historyLow prevalence
2011
Colonization with antibiotic-susceptible strains protects against methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition: a nested case-control study
Huang SS, Datta R, Rifas-Shiman S, Kleinman K, Placzek H, Lankiewicz JD, Platt R. Colonization with antibiotic-susceptible strains protects against methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition: a nested case-control study. Critical Care 2011, 15: r210. PMID: 21914221, PMCID: PMC3334754, DOI: 10.1186/cc10445.Peer-Reviewed Original ResearchConceptsMethicillin-resistant Staphylococcus aureusMethicillin-sensitive Staphylococcus aureusVancomycin-resistant enterococciInitial negative swabCase-control studyVancomycin-sensitive enterococciMRSA acquisitionVRE acquisitionICU admissionRisk factorsNegative swabsStaphylococcus aureusHigh endemic settingMRSA-positive patientsVancomycin-resistant enterococci acquisitionThird-generation cephalosporinsSensitive strainsPredictors of acquisitionBilateral naresMSSA carriageMSSA infectionsSame hospitalizationICU patientsLow albuminMRSA infectionEnvironmental Cleaning Intervention and Risk of Acquiring Multidrug-Resistant Organisms From Prior Room Occupants
Datta R, Platt R, Yokoe DS, Huang SS. Environmental Cleaning Intervention and Risk of Acquiring Multidrug-Resistant Organisms From Prior Room Occupants. JAMA Internal Medicine 2011, 171: 491-494. PMID: 21444840, DOI: 10.1001/archinternmed.2011.64.Peer-Reviewed Original ResearchConceptsMethicillin-resistant Staphylococcus aureusRisk of acquisitionPrior room occupantsVancomycin-resistant enteroccociIntensive care unitCare unitIntervention periodAcquisition of MRSAIntensive care unit roomsRetrospective cohort studyMultidrug-resistant organismsAcademic medical centerEnvironmental cleaning interventionsVRE acquisitionEligible patientsMRSA carriersVRE transmissionCardiac surgeryCohort studyMRSA acquisitionNeurosurgery unitThoracic surgeryMedical CenterVRE carriersGeneral surgery