2024
Retinal integrity in human babesiosis: a pilot study
Dionne E, Adelman R, Cekic O, Golden M, Moffarah A, Krause P, Farhadian S. Retinal integrity in human babesiosis: a pilot study. BMC Ophthalmology 2024, 24: 310. PMID: 39048971, PMCID: PMC11267664, DOI: 10.1186/s12886-024-03568-6.Peer-Reviewed Original ResearchConceptsEvidence of retinopathyNo study patientRetina of patientsCohort of patientsAbnormal vessel formationComplication of babesiosisRetinal tearsRetinal inflammationRetinal eye examResultsTen patientsRetinal integrityRetinal examinationRetinal bleedingIndirect ophthalmoscopeRetinal abnormalitiesStudy patientsChart reviewCase reportEye examPilot studyPatientsAnimal studiesSmall studyClinical informationHuman babesiosis
2020
National Trends in the United States Eye Care Workforce from 1995 to 2017
Feng PW, Ahluwalia A, Feng H, Adelman RA. National Trends in the United States Eye Care Workforce from 1995 to 2017. American Journal Of Ophthalmology 2020, 218: 128-135. PMID: 32445703, DOI: 10.1016/j.ajo.2020.05.018.Peer-Reviewed Original ResearchConceptsEye care workforceOphthalmologist densityYears of ageRural countiesEye care providersArea Health Resource FileCare workforceCross-sectional studyHealth care infrastructureRatio of ophthalmologistsMAIN OUTCOMECare providersMean annual increaseOphthalmologistsNumber of providersOptometristsCare infrastructureHealth insuranceResource FileYoung ophthalmologistsNational trendsCounty characteristicsGreater proportionAgeMetropolitan counties
2018
Educational and Scholarly Opportunities for Medical Students and Residents in Professional Ophthalmology Organizations.
Yang A, Zhang X, Liu J, Chow J, Adelman R, Forster S. Educational and Scholarly Opportunities for Medical Students and Residents in Professional Ophthalmology Organizations. JAMA Ophthalmology 2018, 136: 1417-1419. PMID: 30326048, PMCID: PMC6594420, DOI: 10.1001/jamaophthalmol.2018.3963.Peer-Reviewed Original Research
2017
Vitrectomy in the management of diabetic macular edema in treatment-naïve patients
Michalewska Z, Stewart MW, Landers MB, Bednarski M, Adelman RA, Nawrocki J. Vitrectomy in the management of diabetic macular edema in treatment-naïve patients. Canadian Journal Of Ophthalmology 2017, 53: 402-407. PMID: 30119796, DOI: 10.1016/j.jcjo.2017.10.011.Peer-Reviewed Original ResearchConceptsTreatment-naïve diabetic macular edemaDiabetic macular edemaCentral retinal thicknessPars plana vitrectomyMacular edemaVisual acuityPlana vitrectomyMean central retinal thicknessDuration of diabetesProspective randomized trialsTreatment-naïve patientsInitial visual acuityVisual acuity changesPrimary outcome measureEfficacy of vitrectomyElectronic medical recordsEarly vitrectomyIntravitreal bevacizumabFinal BCVAMean BCVAPrimary endpointRetinal thicknessConsecutive patientsRandomized trialsRetrospective study
2016
Trends of Anti-Vascular Endothelial Growth Factor Use in Ophthalmology Among Privately Insured and Medicare Advantage Patients
Parikh R, Ross JS, Sangaralingham LR, Adelman RA, Shah ND, Barkmeier AJ. Trends of Anti-Vascular Endothelial Growth Factor Use in Ophthalmology Among Privately Insured and Medicare Advantage Patients. Ophthalmology 2016, 124: 352-358. PMID: 27890437, DOI: 10.1016/j.ophtha.2016.10.036.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAngiogenesis InhibitorsBevacizumabCohort StudiesDatabases, FactualDiabetic RetinopathyDrug UtilizationFemaleHumansInsurance, HealthIntravitreal InjectionsMacular DegenerationMaleMedicare Part CMiddle AgedOphthalmologyPrivate SectorRanibizumabReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsRetinal Vein OcclusionRetrospective StudiesUnited StatesVascular Endothelial Growth Factor AYoung AdultConceptsAge-related macular degenerationDiabetic retinal diseaseAnti-VEGF injectionsIntravitreal anti-VEGF injectionsRetinal vein occlusionAdministrative claims dataRetinal diseasesOphthalmic diseasesVein occlusionClaims dataUse of bevacizumabCurrent Procedural Terminology codesPatients 18 yearsRetrospective cohort studyMedicare Advantage patientsOptumLabs Data WarehouseDrug Administration approvalProcedural Terminology codesGrowth factor useRanibizumab useBevacizumab useAvailable medicationsCohort studyMedication useCommon medications
2015
CHOROIDAL THICKNESS MEASURED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY BEFORE AND AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING FOR IDIOPATHIC EPIRETINAL MEMBRANES
Michalewska Z, Michalewski J, Adelman RA, Zawilak E, Nawrocki J. CHOROIDAL THICKNESS MEASURED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY BEFORE AND AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING FOR IDIOPATHIC EPIRETINAL MEMBRANES. Retina 2015, 35: 487-491. PMID: 25322467, DOI: 10.1097/iae.0000000000000350.Peer-Reviewed Original ResearchConceptsIdiopathic epiretinal membraneOuter choroidoscleral boundaryChoroidal thicknessFellow eyesEpiretinal membraneMembrane peelingINTERNAL LIMITING MEMBRANE PEELINGPatient's fellow eyeUnaffected fellow eyesPars plana vitrectomyChoroidal thickness measurementsRetinal pigment epitheliumSource optical coherence tomographyOptical coherence tomographySuprachoroidal layerOperated eyesRetinal arteryPlana vitrectomyProspective studyERM removalPigment epitheliumHyperreflective bandSource optical coherence tomography imagesCoherence tomographySuprachoroidal space
2014
Clinical Variables Associated with Failure of Retinal Detachment Repair The European Vitreo-Retinal Society Retinal Detachment Study Report Number 4
Adelman RA, Parnes AJ, Michalewska Z, Ducournau D, Group E. Clinical Variables Associated with Failure of Retinal Detachment Repair The European Vitreo-Retinal Society Retinal Detachment Study Report Number 4. Ophthalmology 2014, 121: 1715-1719. PMID: 24766870, DOI: 10.1016/j.ophtha.2014.03.012.Peer-Reviewed Original ResearchConceptsRetinal detachment repairRhegmatogenous retinal detachment repairChoroidal detachmentDetachment repairProliferative vitreoretinopathySignificant hypotonyRetinal breaksDetached quadrantsGrade CGrade BPrimary rhegmatogenous retinal detachment repairPreoperative clinical findingsSmall retinal breaksRhegmatogenous retinal detachmentFailure rateGiant retinal breaksIndependent explanatory variablesPVR statusSurgical failureRetinal detachmentGiant tearsSubretinal fluidClinical findingsClinical variablesAnatomic reattachment
2013
Prevalence of Ocular Manifestations of HIV/AIDS in the Highly Active Antiretroviral Therapy (HAART) Era: A Different Spectrum in Central South China
Luo J, Jing D, Kozak I, Huiming Z, Siying C, Yezhen Y, xin Q, Luosheng T, Adelman RA, Forster SH. Prevalence of Ocular Manifestations of HIV/AIDS in the Highly Active Antiretroviral Therapy (HAART) Era: A Different Spectrum in Central South China. Ophthalmic Epidemiology 2013, 20: 170-175. PMID: 23713918, DOI: 10.3109/09286586.2013.789530.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAntiretroviral Therapy, Highly ActiveAsian PeopleCD4 Lymphocyte CountCD4-Positive T-LymphocytesChildChinaCross-Sectional StudiesCytomegalovirus RetinitisEye Infections, ViralFemaleHIV InfectionsHumansMaleMiddle AgedPrevalenceRetinal DiseasesRisk FactorsVisual AcuityYoung AdultConceptsHIV/AIDSOcular manifestationsActive antiretroviral therapy (HAART) eraHuman immunodeficiency virus/Antiretroviral therapy eraActive antiretroviral therapyRoutine ophthalmic examinationEra of HAARTPrevalence of HIVCross-sectional studyHIV retinopathyTherapy eraAntiretroviral therapyCommon HIVCytomegalovirus retinitisOcular complicationsOcular examinationOcular findingsImmunodeficiency syndromeOcular lesionsOphthalmic examinationVirus/Epidemiologic studiesHigh riskOcular diseases
2012
ACUTE SYPHILITIC POSTERIOR PLACOID CHORIORETINITIS
Eandi CM, Neri P, Adelman RA, Yannuzzi LA, Cunningham ET. ACUTE SYPHILITIC POSTERIOR PLACOID CHORIORETINITIS. Retina 2012, 32: 1915-1941. PMID: 22863970, DOI: 10.1097/iae.0b013e31825f3851.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAnti-Bacterial AgentsCD4 Lymphocyte CountChorioretinitisColoring AgentsDrug Therapy, CombinationEye Infections, BacterialFemaleFluorescein AngiographyFluorescent Treponemal Antibody-Absorption TestGlucocorticoidsHIV SeropositivityHumansIndocyanine GreenInfusions, IntravenousMaleMiddle AgedPenicillin GRetrospective StudiesSyphilisTomography, Optical CoherenceVisual AcuityConceptsAcute syphilitic posterior placoid chorioretinitisPosterior placoid chorioretinitisCD4 cell countCells/μLAntibiotic therapyAngiographic featuresFluorescein angiographyPositive venereal disease research laboratoryCell countHuman immunodeficiency virus (HIV) coinfectionMedian CD4 cell countRapid plasma regain titerRecent CD4 cell countVenereal Disease Research LaboratoryFluorescent treponemal antibody absorptionEvidence of neurosyphilisMulticenter chart reviewOuter retinal lesionsImmunodeficiency virus coinfectionAppropriate antibiotic therapyPosterior segment examinationSeries of patientsHuman immunodeficiency virusPositive serologic testsRed-free photographsIs Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic Neuropathy?
Prescott CR, Sklar CA, Lesser RL, Adelman RA. Is Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic Neuropathy? Journal Of Neuro-Ophthalmology 2012, 32: 51-53. PMID: 22269947, DOI: 10.1097/wno.0b013e318240596e.Peer-Reviewed Original ResearchConceptsNonarteritic anterior ischemic optic neuropathyAnterior ischemic optic neuropathyIschemic optic neuropathyVisual acuityIntravitreal bevacizumabOptic neuropathyTreatment optionsIntravitreal bevacizumab injectionEffective treatment optionVisual field defectsBevacizumab injectionFellow eyesClinical outcomesRetrospective studyTreatment modalitiesNatural courseField defectsPatientsDecreased acuitySmall seriesAcuityBevacizumabProfound lossVisual fieldNeuropathy
2011
Proliferation of the ciliary epithelium with retinal neuronal and photoreceptor cell differentiation in human eyes with retinal detachment and proliferative vitreoretinopathy
Ducournau Y, Boscher C, Adelman RA, Guillaubey C, Schmidt-Morand D, Mosnier JF, Ducournau D. Proliferation of the ciliary epithelium with retinal neuronal and photoreceptor cell differentiation in human eyes with retinal detachment and proliferative vitreoretinopathy. Graefe's Archive For Clinical And Experimental Ophthalmology 2011, 250: 409-423. PMID: 21932075, DOI: 10.1007/s00417-011-1797-3.Peer-Reviewed Original ResearchMeSH KeywordsAC133 AntigenAdultAntigens, CDCell DifferentiationCell MovementCell ProliferationCiliary BodyErbB ReceptorsFemaleGlial Fibrillary Acidic ProteinGlycoproteinsHumansImmunoenzyme TechniquesKi-67 AntigenMaleMiddle AgedParaffin EmbeddingPeptidesPhosphopyruvate HydratasePhotoreceptor Cells, VertebratePigment Epithelium of EyeRetinal DetachmentRetinal NeuronsRhodopsinVitreoretinopathy, ProliferativeConceptsAnterior proliferative vitreoretinopathyRetinal detachmentAdult human eyeProliferative vitreoretinopathyCiliary bodyRetinal progenitor cellsControl eyesAdult ciliary bodyCE cellsMethodsThe present studyHuman eyeRetinal transplantationEndoscopic evaluationGFAP stainingCiliary epithelial cellsPhotoreceptor lineageOrbital tumorsVitreous baseNormal eyesDetached retinaStrong stainingGlial formationCiliary epitheliumConclusionsOur observationsDonor cellsThe Treatment of Recurrent Central Serous Chorioretinopathy with Intravitreal Bevacizumab
Lee ST, Adelman RA. The Treatment of Recurrent Central Serous Chorioretinopathy with Intravitreal Bevacizumab. Journal Of Ocular Pharmacology And Therapeutics 2011, 27: 611-614. PMID: 21810026, DOI: 10.1089/jop.2011.0045.Peer-Reviewed Original ResearchConceptsRecurrent central serous chorioretinopathyMean central macular thicknessCentral macular thicknessCentral serous chorioretinopathyPreinjection visual acuityVisual acuityOptical coherence tomographyIntravitreal bevacizumabSerous chorioretinopathyTreatment optionsLow-risk treatment optionYale Eye CenterIntravitreal bevacizumab injectionRetrospective case seriesEffective treatment optionLong-term efficacySub-retinal fluidNumber of injectionsFluorescein angiography imagingBevacizumab injectionRecurrent diseaseMacular thicknessMonth 3Month 6Case series
2010
High-Altitude Retinopathy and Optical Coherence Tomography Findings
Seth RK, Adelman RA. High-Altitude Retinopathy and Optical Coherence Tomography Findings. Seminars In Ophthalmology 2010, 25: 13-15. PMID: 20507191, DOI: 10.3109/08820538.2010.481560.Peer-Reviewed Original ResearchConceptsHigh-altitude retinopathyHigh-altitude cerebral edemaCerebral edemaLife-threatening high-altitude cerebral edemaOptical coherence tomography findingsHigh-altitude illnessAltitude cerebral edemaAcute mountain sicknessOptical coherence tomographyReview of literatureTomography findingsOCT findingsCase reportClinical syndromeAltitude illnessMountain sicknessCoherence tomographyEdemaRetinopathyImportant entityPatientsReviewSyndromeIllnessFindings
2008
Ocular trauma resulting from paintball injury
Pahk PJ, Adelman RA. Ocular trauma resulting from paintball injury. Graefe's Archive For Clinical And Experimental Ophthalmology 2008, 247: 469. PMID: 19034480, DOI: 10.1007/s00417-008-0985-2.Peer-Reviewed Original ResearchConceptsProper eye protectionIntraocular foreign bodyOcular injuriesLoss of visionVisual acuityPaintball injuriesProliferative vitreoretinopathyEye protectionSignificant ocular injuryFinal visual acuitySevere ocular injuryTertiary referral centerSubluxation of lensLens injuryMethodsRetrospective reviewSecondary glaucomaCommotio retinaeOcular traumaReferral centerEye injuriesRetinal hemorrhagesVitreous hemorrhageChoroidal ruptureIris injuryRetinal tearsCorrelation between foveal structure and visual outcome following macular hole surgery: a spectral optical coherence tomography study
Michalewska Z, Michalewski J, Cisiecki S, Adelman R, Nawrocki J. Correlation between foveal structure and visual outcome following macular hole surgery: a spectral optical coherence tomography study. Graefe's Archive For Clinical And Experimental Ophthalmology 2008, 246: 823-830. PMID: 18386040, DOI: 10.1007/s00417-007-0764-5.Peer-Reviewed Original ResearchConceptsMacular hole surgerySpectral optical coherence tomographyHole surgeryRetinal layersGood postoperative visual acuityOptical coherence tomography studyNerve fiber layer defectsFull-thickness macular holeNormal foveal thicknessPostoperative visual acuityFinal functional outcomeOuter retinal layersPars plana vitrectomyMacular hole closurePhotoreceptor layer defectsPhotoreceptor defectsOptical coherence tomographyLayer defectsFoveal thicknessRetinal thicknessVisual outcomePlana vitrectomyVisual acuityFunctional outcomeTrypan blue staining
2007
Ethambutol Neuroretinopathy
Vistamehr S, Walsh TJ, Adelman RA. Ethambutol Neuroretinopathy. Seminars In Ophthalmology 2007, 22: 141-146. PMID: 17763233, DOI: 10.1080/08820530701457134.Peer-Reviewed Original ResearchConceptsElectrophysiological findingsRetinal pigment epithelial changesAbnormal Arden ratioElectro-oculogram findingsFlame-shaped hemorrhagesPigment epithelial changesFull-field ERGAbnormal wave patternRetinal findingsElectroretinogram findingsMacular edemaClinical featuresEpithelial changesCase reportOcular toxicityPattern ERGArden ratioNeuroretinopathyVisual fieldToxic effectsFindingsEdemaHemorrhagePatientsEthambutol
2005
The Effectiveness of Isobutyl Cyanoacrylate Tissue Adhesive for the Treatment of Corneal Perforations
Setlik DE, Seldomridge DL, Adelman RA, Semchyshyn TM, Afshari NA. The Effectiveness of Isobutyl Cyanoacrylate Tissue Adhesive for the Treatment of Corneal Perforations. American Journal Of Ophthalmology 2005, 140: 920-921. PMID: 16310475, DOI: 10.1016/j.ajo.2005.04.062.Peer-Reviewed Original ResearchRisk Factors for Progression to Penetrating Keratoplasty in Patients With Keratoconus
Reeves SW, Stinnett S, Adelman RA, Afshari NA. Risk Factors for Progression to Penetrating Keratoplasty in Patients With Keratoconus. American Journal Of Ophthalmology 2005, 140: 607.e1-607.e6. PMID: 16226512, DOI: 10.1016/j.ajo.2005.05.029.Peer-Reviewed Original ResearchConceptsCorneal transplantationRisk factorsDemographic risk factorsKeratoconus patientsAverage keratometryMultivariate analysisDuke University Eye CenterSignificant univariate risk factorsRisks of transplantationUniversity Eye CenterTertiary referral centerDisease 5 yearsUnivariate risk factorsSignificant risk factorsCase-control studyHigher keratometry valuesReferral centerKeratoconic patientsVisual acuityClinical indicatorsKeratoconic eyesRisk groupsKeratometry valuesEye CenterTransplantation
2004
Bilateral intraocular foreign bodies simulating crystalline lens
Hagedorn CL, Tauber S, Adelman RA. Bilateral intraocular foreign bodies simulating crystalline lens. American Journal Of Ophthalmology 2004, 138: 146-147. PMID: 15234299, DOI: 10.1016/j.ajo.2004.01.046.Peer-Reviewed Original ResearchConceptsIntraocular foreign bodyForeign bodyCrystalline lensRight eyeCT scanComputed tomographyOpen globe repairRetinal detachment surgeryMotor vehicle accidentsGlobe repairDetachment surgeryPlana vitrectomyCase reportCataract extractionMissile injuriesCorneal graftingVehicle accidentsPatientsHigh radiodensityScansEyesPiece of glassVitrectomyLacerationSurgery
2003
Cataract formation after initial trabeculectomy in young patients
Adelman RA, Brauner SC, Afshari NA, Grosskreutz CL. Cataract formation after initial trabeculectomy in young patients. Ophthalmology 2003, 110: 625-629. PMID: 12623833, DOI: 10.1016/s0161-6420(02)01769-4.Peer-Reviewed Original ResearchConceptsInitial trabeculectomyYounger patientsCataract extractionCataract formationType of glaucomaNoncomparative case seriesMain outcome measuresSteroid-induced glaucomaLens statusCommon complicationFirst eyeFellow eyesCase seriesCataract progressionEar InfirmaryLenticular opacificationLenticular opacitiesOutcome measuresMAIN OUTCOMETrabeculectomyMassachusetts EyePatientsConsultation serviceSignificant riskMonths