2023
Awareness and Uptake of Pre-Exposure Prophylaxis (PrEP) for HIV Prevention Among Men who have Sex with Men in Nepal
Paudel K, Kanak M, Gautam K, Bhandari P, Dhakal M, Wickersham J, Valente P, Ha T, Shrestha R. Awareness and Uptake of Pre-Exposure Prophylaxis (PrEP) for HIV Prevention Among Men who have Sex with Men in Nepal. Journal Of Community Health 2023, 49: 514-525. PMID: 38127298, DOI: 10.1007/s10900-023-01318-1.Peer-Reviewed Original ResearchPre-exposure prophylaxisPrEP awarenessBiomedical prevention strategiesHIV transmission riskUse of PrEPCross-sectional surveyHealth insurance coveragePrEP knowledgePrEP useHIV preventionStudy populationPrevention strategiesHealthcare providersBivariate analysisLogistic regressionTransmission riskPrEPMSMInsurance coverageProphylaxisHIVMenParticipantsInnovative strategiesInfectionPre-exposure prophylaxis service among men who have sex with men in Malaysia: findings from a discrete choice experiment
Dubov A, Altice F, Gutierrez J, Wickersham J, Azwa I, Kamarulzaman A, Gautam K, Shrestha R. Pre-exposure prophylaxis service among men who have sex with men in Malaysia: findings from a discrete choice experiment. Scientific Reports 2023, 13: 14200. PMID: 37648731, PMCID: PMC10468492, DOI: 10.1038/s41598-023-41264-5.Peer-Reviewed Original ResearchConceptsInjectable PrEPPre-exposure prophylaxis servicesDaily oral PrEPPre-exposure prophylaxisMalaysian MSMPrEP deliveryOral PrEPPrEP uptakeMSMPrEPLatent class analysisDiscrete choice experimentMenDelivery preferencesDelivery programsSexGroupClass analysisType of programPreference groupsOnline surveyProphylaxisInitiation rateHIVDosingBarriers and Facilitators to Pre-Exposure Prophylaxis by Men Who Have Sex with Men and Community Stakeholders in Malaysia
Rosen A, Wickersham J, Altice F, Khati A, Azwa I, Tee V, Jeri-Wahrhaftig A, Luces J, Ni Z, Kamarulzaman A, Saifi R, Shrestha R. Barriers and Facilitators to Pre-Exposure Prophylaxis by Men Who Have Sex with Men and Community Stakeholders in Malaysia. International Journal Of Environmental Research And Public Health 2023, 20: 5669. PMID: 37174187, PMCID: PMC10177799, DOI: 10.3390/ijerph20095669.Peer-Reviewed Original ResearchConceptsPre-exposure prophylaxisPrEP providersNominal group techniqueMalaysian MSMEvidence-based HIV prevention strategiesPatient-centered decision aidAwareness of PrEPHIV prevention strategiesPotential new strategyPrEP deliveryPrEP carePrEP initiationPrEP servicesPrEP uptakeDecision aidPrevention strategiesUnderstanding of barriersComplex clinical protocolsClinical protocolsMSMQualitative focus groupsCommunity stakeholdersPrEPProphylaxisMen
2022
Using nominal group technique to identify barriers and facilitators to preventing HIV using combination same-day pre-exposure prophylaxis and medications for opioid use disorder
Eger WH, Altice FL, Lee J, Vlahov D, Khati A, Osborne S, Wickersham JA, Bohonnon T, Powell L, Shrestha R. Using nominal group technique to identify barriers and facilitators to preventing HIV using combination same-day pre-exposure prophylaxis and medications for opioid use disorder. Harm Reduction Journal 2022, 19: 120. PMID: 36307817, PMCID: PMC9616614, DOI: 10.1186/s12954-022-00703-8.Peer-Reviewed Original ResearchConceptsSame-day prescriptionPre-exposure prophylaxisOpioid use disorderHIV transmissionUse disordersClinical stakeholdersAvailability of providersSystems of careHealth care systemCoordinated careNew practice modelClinical careMedicationsPharmacy deliveryMOUDNominal group techniqueLocal prescribersPWIDSexual riskPrEPCare systemHealth benefitsCareMultiple visitsProphylaxisExploring drivers of pre-exposure prophylaxis uptake among gay, bisexual, and other men who have sex with men in Malaysia
Eger WH, Adaralegbe A, Khati A, Azwa I, Wickersham JA, Osborne S, Shrestha R. Exploring drivers of pre-exposure prophylaxis uptake among gay, bisexual, and other men who have sex with men in Malaysia. International Journal Of STD & AIDS 2022, 33: 821-828. PMID: 35772943, PMCID: PMC10069270, DOI: 10.1177/09564624221106535.Peer-Reviewed Original ResearchConceptsPre-exposure prophylaxisPrEP useHIV prevention strategiesMultivariable logistic modelHigh-risk behaviorsMalaysian MSMPrEP uptakeMultivariable analysisHIV epidemicHealthcare engagementPrevention strategiesHealth systemSexual intercourseRM 3000PrEPProphylaxisSexual behaviorHIVMenMonthly incomeMSMMonthsHigh awarenessSexLogistic model
2021
Limited Risk Compensation Among Women Who Inject Drugs: Results From the Project Sexual Health Equity Preexposure Prophylaxis Demonstration Study in Philadelphia
Tran NK, Van Der Pol B, Shrestha R, Bazzi AR, Bellamy SL, Sherman SG, Roth AM. Limited Risk Compensation Among Women Who Inject Drugs: Results From the Project Sexual Health Equity Preexposure Prophylaxis Demonstration Study in Philadelphia. Sexually Transmitted Diseases 2021, 49: e64-e66. PMID: 34694276, PMCID: PMC9018480, DOI: 10.1097/olq.0000000000001577.Peer-Reviewed Original ResearchUse of Pre-exposure Prophylaxis Among People Who Inject Drugs: Exploratory Findings of the Interaction Between Race, Homelessness, and Trust
Zhou X, Altice FL, Chandra D, Didomizio E, Copenhaver MM, Shrestha R. Use of Pre-exposure Prophylaxis Among People Who Inject Drugs: Exploratory Findings of the Interaction Between Race, Homelessness, and Trust. AIDS And Behavior 2021, 25: 3743-3753. PMID: 33751313, DOI: 10.1007/s10461-021-03227-7.Peer-Reviewed Original ResearchConceptsPre-exposure prophylaxisPrEP useProvider trustPatient-level factorsOpioid-dependent patientsLogistic regression analysisNon-homeless participantsHomeless participantsRace/ethnicityEligibility criteriaCross-sectional dataPrEPProphylaxisMethadoneRegression analysisDrugsExploratory findingsParticipantsPotential moderatorsPWIDPatientsSignificant moderatorWillingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment
Ni Z, Altice FL, Wickersham JA, Copenhaver MM, DiDomizio EE, Nelson LE, Shrestha R. Willingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment. Drug And Alcohol Dependence 2021, 219: 108477. PMID: 33422864, PMCID: PMC7946167, DOI: 10.1016/j.drugalcdep.2020.108477.Peer-Reviewed Original ResearchConceptsOpioid-dependent individualsPre-exposure prophylaxisPrEP useHIV riskHealthcare providersSex-related risk behaviorsMultivariable logistic regression analysisAwareness of PrEPUrban methadone clinicMultiple logistic regressionDisproportionate HIV burdenLogistic regression analysisCross-sectional surveyHIV burdenHIV infectionHIV testingIndependent correlatesMethadone clinicsDrug treatmentRisk behaviorsLogistic regressionPrEPPrevious useHigher likelihoodProphylaxisChapter 11 HIV pre-exposure prophylaxis for people who inject drugs
Shrestha R, McCoy-Redd B, Meyer J. Chapter 11 HIV pre-exposure prophylaxis for people who inject drugs. 2021, 223-236. DOI: 10.1016/b978-0-323-68328-9.00011-4.Peer-Reviewed Original ResearchHIV preventionEffective HIV prevention toolHigh-risk sexual networksHIV pre-exposure prophylaxisLimited clinical trial dataSubstance usePre-exposure prophylaxisHIV prevention toolClinical trial dataHarm reduction programsKey target populationSubstance use disordersPart of patientsTarget populationPrEP outcomesPreexposure prophylaxisMedication adherenceHIV riskUse disordersTrial dataPWIDSexual networksPrEPPrevention toolProphylaxis
2020
The Pre-exposure Prophylaxis (PrEP) Care Cascade in People Who Inject Drugs: A Systematic Review
Mistler CB, Copenhaver MM, Shrestha R. The Pre-exposure Prophylaxis (PrEP) Care Cascade in People Who Inject Drugs: A Systematic Review. AIDS And Behavior 2020, 25: 1490-1506. PMID: 32749627, PMCID: PMC7858689, DOI: 10.1007/s10461-020-02988-x.Peer-Reviewed Original ResearchConceptsPre-exposure prophylaxisCare cascadeSystematic reviewInjection drug useTransmission of HIVKey risk factorsPrEP eligibilityPrEP carePrEP uptakeHIV incidenceHIV transmissionRisk factorsPRISMA guidelinesPrevention strategiesPWIDDrug useLiterature searchEfficacious strategyProphylaxisPrEPDrugsInterventionHigh awarenessHIVReviewFeasibility and Acceptability of an mHealth-Based Approach as an HIV Prevention Strategy Among People Who Use Drugs on Pre-Exposure Prophylaxis
Shrestha R, Altice FL, DiDomizio E, Sibilio B, Ranjit YS, Copenhaver MM. Feasibility and Acceptability of an mHealth-Based Approach as an HIV Prevention Strategy Among People Who Use Drugs on Pre-Exposure Prophylaxis. Patient Preference And Adherence 2020, 14: 107-118. PMID: 32021122, PMCID: PMC6971384, DOI: 10.2147/ppa.s236794.Peer-Reviewed Original ResearchPre-exposure prophylaxisHIV risk reductionHIV preventionText messaging servicePrimary HIV preventionHIV prevention strategiesOpioid-dependent peopleReminder text messagesWeekly text messagesPost-intervention assessmentRisk reductionForty HIVPrEP adherenceText messagesSMS remindersRisk groupsText remindersPrevention strategiesUnderserved populationsMHealth technologiesAcceptability studyHealth carePreventionProphylaxisPreliminary evidence
2019
Influence of Stigma on Pre-Exposure Prophylaxis (PrEP) Care Continuum Among Men and Transwomen Who Have Sex with Men (MTWSM) in the United States.
Ssenyonjo J, Shrestha R, Copenhaver M. Influence of Stigma on Pre-Exposure Prophylaxis (PrEP) Care Continuum Among Men and Transwomen Who Have Sex with Men (MTWSM) in the United States. International Journal Of HIV/AIDS Prevention Education And Behavioural Science 2019, 5: 134-140. PMID: 38827018, PMCID: PMC11140821, DOI: 10.11648/j.ijhpebs.20190502.18.Peer-Reviewed Original Research
2018
Exploring the Use of Pre-exposure Prophylaxis (PrEP) for HIV Prevention Among High-Risk People Who Use Drugs in Treatment
Shrestha R, Copenhaver M. Exploring the Use of Pre-exposure Prophylaxis (PrEP) for HIV Prevention Among High-Risk People Who Use Drugs in Treatment. Frontiers In Public Health 2018, 6: 195. PMID: 30062091, PMCID: PMC6054971, DOI: 10.3389/fpubh.2018.00195.Peer-Reviewed Original ResearchPre-exposure prophylaxisPrEP adherenceHIV preventionHigh-risk PWUDSubstance abuse treatment settingsUse of PrEPHigh-risk peopleHIV risk behaviorsHIV prevention approachesPrEP servicesDaily dosingPrEP useHigh adherenceDepth semi-structured qualitative interviewsSemi-structured qualitative interviewsTreatment settingsPocket costsRisk behaviorsDisclosure statusPrEPAdherencePrevention approachesProphylaxisPreliminary evidencePWUD
2017
Intent to Use Preexposure Prophylaxis (PrEP), HIV Risk Behaviors, and Self-Report Neurocognitive Symptoms by High-Risk Drug Users: A Mediation Analysis
Shrestha R, Karki P, Huedo-Medina TB, Copenhaver M. Intent to Use Preexposure Prophylaxis (PrEP), HIV Risk Behaviors, and Self-Report Neurocognitive Symptoms by High-Risk Drug Users: A Mediation Analysis. Journal Of The Association Of Nurses In AIDS Care 2017, 28: 612-621. PMID: 28478870, PMCID: PMC7451137, DOI: 10.1016/j.jana.2017.04.005.Peer-Reviewed Original ResearchConceptsHIV risk behaviorsNeurocognitive impairmentRisk behaviorsPreexposure prophylaxisSelf-reported neurocognitive symptomsHigh-risk drug usersHigh-risk PWUDPrEP uptakeNeurocognitive symptomsHIV riskDrug usersSimilar outcomesUnderserved populationsSignificant correlatesProphylaxisImportant unanswered questionsPreliminary evidencePrEPDissemination effortsMediation analysisUnanswered questionsVariables of interestHIVSymptomsClinicians