2023
Application of the multiphase optimisation strategy (MOST) to optimise HIV prevention targeting people on medication for opioid use disorder (MOUD) who have cognitive dysfunction: protocol for a MOST study
Mistler C, Shrestha R, Gunstad J, Collins L, Madden L, Huedo-Medina T, Sibilio B, Copenhaver N, Copenhaver M. Application of the multiphase optimisation strategy (MOST) to optimise HIV prevention targeting people on medication for opioid use disorder (MOUD) who have cognitive dysfunction: protocol for a MOST study. BMJ Open 2023, 13: e071688. PMID: 37399447, PMCID: PMC10314648, DOI: 10.1136/bmjopen-2023-071688.Peer-Reviewed Original ResearchConceptsOpioid use disorderMultiphase optimization strategyCognitive dysfunctionHIV preventionUse disordersPromising biomedical interventionsPre-exposure prophylaxisHIV incidence ratesHIV risk reductionHIV prevention interventionsDrug treatment settingsInstitutional review boardInformed consent formPrEP adherenceHIV prevention contentHIV infectionPrEP uptakeStudy protocolIncidence rateRisk groupsPrevention interventionsPWIDTreatment settingsReview boardEffective interventionsThe Mediating Effect of Changes in Depression Symptoms on the Relationship between Health-Related Quality of Life and Alcohol Consumption: Findings from a Longitudinal Study among Men Living with HIV in India
Ha T, Shi H, Shrestha R, Gaikwad S, Joshi K, Padiyar R, Schensul S. The Mediating Effect of Changes in Depression Symptoms on the Relationship between Health-Related Quality of Life and Alcohol Consumption: Findings from a Longitudinal Study among Men Living with HIV in India. International Journal Of Environmental Research And Public Health 2023, 20: 5567. PMID: 37107849, PMCID: PMC10138320, DOI: 10.3390/ijerph20085567.Peer-Reviewed Original ResearchConceptsHealth-related qualityMale PLWHDepressive symptomsAlcohol useDepression symptomsAlcohol consumptionImproved health-related qualityLower health-related qualityMental healthAntiretroviral therapy adherenceQuality of lifeHeavy alcohol useART adherenceHIV infectionTherapy adherenceClinical trialsIntervention groupIntervention participantsPLWHLower alcohol useControl groupSymptomsHRQoLControl participantsDemographic characteristics
2021
Willingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment
Ni Z, Altice FL, Wickersham JA, Copenhaver MM, DiDomizio EE, Nelson LE, Shrestha R. Willingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment. Drug And Alcohol Dependence 2021, 219: 108477. PMID: 33422864, PMCID: PMC7946167, DOI: 10.1016/j.drugalcdep.2020.108477.Peer-Reviewed Original ResearchConceptsOpioid-dependent individualsPre-exposure prophylaxisPrEP useHIV riskHealthcare providersSex-related risk behaviorsMultivariable logistic regression analysisAwareness of PrEPUrban methadone clinicMultiple logistic regressionDisproportionate HIV burdenLogistic regression analysisCross-sectional surveyHIV burdenHIV infectionHIV testingIndependent correlatesMethadone clinicsDrug treatmentRisk behaviorsLogistic regressionPrEPPrevious useHigher likelihoodProphylaxis
2020
Willingness to Use HIV Self-Testing and Associated Factors Among Transgender Women in Malaysia
Shrestha R, Galka JM, Azwa I, Lim SH, Guadamuz TE, Altice FL, Wickersham JA. Willingness to Use HIV Self-Testing and Associated Factors Among Transgender Women in Malaysia. Transgender Health 2020, 5: 182-190. PMID: 32923668, PMCID: PMC7480722, DOI: 10.1089/trgh.2019.0085.Peer-Reviewed Original ResearchTransgender womenSex work clientsKey populationsMultivariable logistic regressionImplementation of HIVHIV Self-TestingCurrent depressive symptomsCross-sectional surveyCorrelates of willingnessHIV screeningHIV infectionMultivariable analysisAssociated FactorsDirect referralCondomless sexHigh riskDepressive symptomsHIVSTLogistic regressionCommunity-based organizationsWomenAdditional researchStaff membersParticipantsSelf-Testing
2016
Willingness to Use Pre-Exposure Prophylaxis (PrEP): An Empirical Test of the Information-Motivation-Behavioral Skills (IMB) Model among High-Risk Drug Users in Treatment
Shrestha R, Altice FL, Huedo-Medina TB, Karki P, Copenhaver M. Willingness to Use Pre-Exposure Prophylaxis (PrEP): An Empirical Test of the Information-Motivation-Behavioral Skills (IMB) Model among High-Risk Drug Users in Treatment. AIDS And Behavior 2016, 21: 1299-1308. PMID: 27990587, PMCID: PMC5380590, DOI: 10.1007/s10461-016-1650-0.Peer-Reviewed Original ResearchConceptsHigh-risk PWUDBehavioral skills modelCommunity-based methadone maintenance treatmentPre-exposure prophylaxis trialsSex-related HIV risk behaviorsHigh-risk drug usersPre-exposure prophylaxisIMB modelMethadone maintenance treatmentEfficacy of PrEPUse of PrEPHIV risk behaviorsKey risk populationsHealth behavior changeHIV acquisitionProphylaxis trialsHIV infectionMaintenance treatmentHIV preventionRisk populationsDrug usersRisk behaviorsPrEPPWUDIntervention developmentAssociation Between Intimate Partner Violence Against Women and HIV-Risk Behaviors
Shrestha R, Copenhaver MM. Association Between Intimate Partner Violence Against Women and HIV-Risk Behaviors. Violence Against Women 2016, 22: 1621-1641. PMID: 26912296, PMCID: PMC5308057, DOI: 10.1177/1077801216628690.Peer-Reviewed Original ResearchConceptsHIV risk behaviorsIntimate partner violenceSignificant global health issueInconsistent condom useAdverse health outcomesSTIs/HIVMultiple sex partnersSafer sexual practicesGlobal health issueHIV infectionHIV riskPartner violenceHealth outcomesSex partnersCondom useDisproportionate burdenEffective interventionsHealth issuesWomenHIVSexual practicesInfectionPotential relationshipRiskThe Impact of Methadone Maintenance Treatment on HIV Risk Behaviors among High-Risk Injection Drug Users: A Systematic Review.
Karki P, Shrestha R, Huedo-Medina TB, Copenhaver M. The Impact of Methadone Maintenance Treatment on HIV Risk Behaviors among High-Risk Injection Drug Users: A Systematic Review. Evidence-based Medicine & Public Health 2016, 2 PMID: 27066590, PMCID: PMC4824190.Peer-Reviewed Original ResearchMethadone maintenance treatmentInjection drug usersSex-related risk behaviorsHIV risk behaviorsRisk behaviorsMaintenance treatmentDrug usersSystematic reviewHigh-risk injection drug usersFuture HIV prevention strategiesRisk Injection Drug UsersSex-related HIV risk behaviorsHigh-risk populationHIV prevention strategiesSignificant decreaseMultiple sex partnersPreventable drugHIV infectionTreatment adherenceHIV riskLower incidenceHigh riskPrevention strategiesSex partnersDrug use