2024
Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis
Ram C, Yousef S, Ma W, Vallabhajosyula I, Singh S, Agarwal R, Milewski R, Assi R, Patel P, Williams M, Geirsson A, Vallabhajosyula P. Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis. Scientific Reports 2024, 14: 4952. PMID: 38418864, PMCID: PMC10902341, DOI: 10.1038/s41598-024-52660-w.Peer-Reviewed Original ResearchConceptsAortic valve replacementSevere aortic stenosisAfrican American raceArea Deprivation IndexAortic stenosisSevere ASArea deprivation index rankAortic valve replacement ratesAmerican raceAortic valve interventionPresentation of sepsisDiagnosis of ASADI groupValve replacementValve interventionDeprived neighbourhoodsAV interventionDisadvantaged neighborhoodsPatientsFemale genderDeprivation indexHigh-ADI groupLow-ADI groupStenosisRace
2023
TAVR explant with aortic root replacement using a homograft for an aortic rupture.
Singh S, Vallabhajosyula P, Geirsson A, Assi R. TAVR explant with aortic root replacement using a homograft for an aortic rupture. Multimedia Manual Of Cardio-Thoracic Surgery 2023, 2023 PMID: 36644957, DOI: 10.1510/mmcts.2022.101.Peer-Reviewed Original ResearchConceptsLeft coronary buttonAortic ruptureCoronary buttonsAortic rootAortic root replacementTranscatheter aortic valve prosthesisAortic valve prosthesisTAVR explantRoot replacementMale presentingCase reportTranscatheter prosthesesValve prosthesisStent frameBovine pericardiumProsthesisRuptureHaemopericardiumPseudoaneurysmHomograftsPresenting
2022
Variability in surveillance practice for patients with diagnosis of bicuspid aortic valve syndrome
Kahler-Quesada A, Vallabhajosyula I, Yousef S, Mori M, Amabile A, Assi R, Geirsson A, Vallabhajosyula P. Variability in surveillance practice for patients with diagnosis of bicuspid aortic valve syndrome. Scientific Reports 2022, 12: 22009. PMID: 36539583, PMCID: PMC9768129, DOI: 10.1038/s41598-022-25571-x.Peer-Reviewed Original ResearchConceptsBicuspid aortic valveTertiary care centerAortic valveCare centerCardiovascular specialistsBicuspid aortic valve syndromeAortic pathologySurveillance imagingDisease progressionPatientsBivariate analysisEchocardiogramGuide interventionDiagnosisHigher proportionValveSurveillance practicesUrgent needGuidelinesValvulopathySpecialistsSurgeryValvularSyndromeFollowDirect relationship between transvalvular velocity and cardiac dysfunction, morbidity, and mortality in patients with aortic stenosis
Yousef S, Amabile A, Ram C, Singh S, Agarwal R, Milewski R, Assi R, Patel P, Krane M, Geirsson A, Vallabhajosyula P. Direct relationship between transvalvular velocity and cardiac dysfunction, morbidity, and mortality in patients with aortic stenosis. Journal Of Cardiac Surgery 2022, 37: 5052-5062. PMID: 36378856, DOI: 10.1111/jocs.17199.Peer-Reviewed Original ResearchConceptsDegree of ASCardiac structural changesAortic stenosisSevere symptomatic aortic stenosisEnd-organ morbiditiesStructural cardiac changesSymptomatic aortic stenosisEnd-organ diseaseKaplan-Meier curvesRisk of mortalityTransvalvular flow velocityCochran-Armitage testCause mortalityPatient characteristicsCardiac changesCardiac dysfunctionPatient morbidityTransvalvular velocityCurrent guidelinesGroup BGroup ACaucasian raceHigh riskCox modelEarly intervention
2021
Development and Validation of a Predictive Model to Identify Patients With an Ascending Thoracic Aortic Aneurysm
Mori M, Gan G, Deng Y, Yousef S, Weininger G, Daggula KR, Agarwal R, Shang M, Assi R, Geirsson A, Vallabhajosyula P. Development and Validation of a Predictive Model to Identify Patients With an Ascending Thoracic Aortic Aneurysm. Journal Of The American Heart Association 2021, 10: e022102. PMID: 34743563, PMCID: PMC8751931, DOI: 10.1161/jaha.121.022102.Peer-Reviewed Original ResearchMeSH KeywordsAortaAorta, ThoracicAortic Aneurysm, ThoracicAortic DissectionAortic ValveCross-Sectional StudiesFemaleHumansConceptsThoracic aortic aneurysmAortic aneurysmPatient riskTomography scanHigher body surface areaTertiary care centerAortic valve diseaseHistory of arrhythmiaAvailable clinical informationBody surface areaScreening of patientsCross-sectional studyRisk prediction algorithmAscending Thoracic Aortic AneurysmsLogistic regression modelsClinical characteristicsAortic dissectionUnique patientsValve diseaseC-statisticFemale sexThoracic aortaCare centerComorbidity variablesMultivariable model
2020
Variations in Anticoagulation Practice Following Bioprosthetic Aortic and Mitral Valve Replacement and Repair
Mori M, Gan G, Bin Mahmood SU, Deng Y, Mullan CW, Assi R, Vallabhajosyula P, Badhwar V, Geirsson A. Variations in Anticoagulation Practice Following Bioprosthetic Aortic and Mitral Valve Replacement and Repair. Journal Of The American College Of Cardiology 2020, 76: 2412-2413. PMID: 33183513, DOI: 10.1016/j.jacc.2020.08.083.Peer-Reviewed Original ResearchAortic Root Surgery Will Benefit From Development of The Society of Thoracic Surgeons Risk Model Reply
Singh S, Assi R, Vallabhajosyula P. Aortic Root Surgery Will Benefit From Development of The Society of Thoracic Surgeons Risk Model Reply. The Annals Of Thoracic Surgery 2020, 110: 1780-1781. PMID: 32710842, DOI: 10.1016/j.athoracsur.2020.05.134.Commentaries, Editorials and LettersBicuspid Aortic Valve Repair: The Art of Objective Valve Analysis
Assi R, Vallabhajosyula P. Bicuspid Aortic Valve Repair: The Art of Objective Valve Analysis. The Annals Of Thoracic Surgery 2020, 111: 1233. PMID: 32673660, DOI: 10.1016/j.athoracsur.2020.06.012.Commentaries, Editorials and LettersMidterm outcomes and durability of sinus segment preservation compared with root replacement for acute type A aortic dissection
Bojko MM, Assi R, Bavaria JE, Suhail M, Habertheuer A, Hu RW, Harmon J, Milewski RK, Desai ND, Szeto WY, Vallabhajosyula P. Midterm outcomes and durability of sinus segment preservation compared with root replacement for acute type A aortic dissection. Journal Of Thoracic And Cardiovascular Surgery 2020, 163: 900-910.e2. PMID: 32620395, DOI: 10.1016/j.jtcvs.2020.04.064.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAortic AneurysmAortic DissectionAortic ValveAortic Valve InsufficiencyBlood Vessel Prosthesis ImplantationCardiac Surgical ProceduresFemaleHumansMaleMiddle AgedPostoperative ComplicationsRecurrenceReoperationRetrospective StudiesRisk AssessmentRisk FactorsSinus of ValsalvaTime FactorsTreatment OutcomeConceptsAcute typeRoot replacementAortic dissectionAortic insufficiencyRoot repairCumulative incidenceReplacement groupPostoperative aortic insufficiencyProximal aortic reoperationsRoot replacement groupMultivariable Cox regressionSinus of ValsalvaLongitudinal mixed modelsAortic reoperationValsalva dimensionsMidterm outcomesRoot dilationCox regressionFunctional outcomeRisk factorsReoperationSinusInsufficiencyDissectionMixed effects models
2019
Resection of noncoronary sinus segment in a nonaneurysmal root: To do or not to do
Assi R, Milewski RK, Bavaria JE, Vallabhajosyula P. Resection of noncoronary sinus segment in a nonaneurysmal root: To do or not to do. Journal Of Thoracic And Cardiovascular Surgery 2019, 157: e321. PMID: 30798957, DOI: 10.1016/j.jtcvs.2019.01.036.Commentaries, Editorials and Letters