TIM-3, a Possible Target for Immunotherapy in Cancer and Chronic Viral Infections.
Tieu R, Amancha P, Villinger F, Byrareddy S. TIM-3, a Possible Target for Immunotherapy in Cancer and Chronic Viral Infections. 2014, 1 PMID: 26539564, PMCID: PMC4629856.Peer-Reviewed Original ResearchChronic viral infectionsTim-3Inhibitory receptorsChronic viral infection modelsEffector T cell responsesExpression of Tim-3Viral infectionCo-inhibitory moleculesT cell responsesCTLA-4PD-1Immune checkpointsCo-stimulatorySoluble factorsInfection modelTherapeutic targetImmunotherapyTumorReceptorsInfectionViral infection modelCancerChronicallyComplex mechanisms