2013
A two-year longitudinal pilot MRI study of the brainstem in autism
Jou RJ, Frazier TW, Keshavan MS, Minshew NJ, Hardan AY. A two-year longitudinal pilot MRI study of the brainstem in autism. Behavioural Brain Research 2013, 251: 163-167. PMID: 23619132, PMCID: PMC4107420, DOI: 10.1016/j.bbr.2013.04.021.Peer-Reviewed Original ResearchConceptsBrainstem volumeMRI studiesLongitudinal MRI studyPilot MRI studyTotal brain volumeBrain growth trajectoriesAge 15 yearsGray matter volumeAtypical growth patternGray matter structuresBrainstem abnormalitiesSignificant group differencesPathobiology of autismBrainstem developmentBilateral increaseMRI volumetrySensory abnormalitiesClinical significanceMatter volumeBrain volumeControl groupStructural MRIBrainstemPilot studyNeurodevelopmental disorders
2010
Enlarged right superior temporal gyrus in children and adolescents with autism
Jou RJ, Minshew NJ, Keshavan MS, Vitale MP, Hardan AY. Enlarged right superior temporal gyrus in children and adolescents with autism. Brain Research 2010, 1360: 205-212. PMID: 20833154, PMCID: PMC2990401, DOI: 10.1016/j.brainres.2010.09.005.Peer-Reviewed Original ResearchConceptsRight superior temporal gyrusSuperior temporal gyrusSuperior temporal gyral volumeTemporal gyrusAutism groupLeft superior temporal gyrusSocial perceptual deficitsNeurodevelopmental disordersTotal brain volumeBrain volumePerceptual deficitsSocial perceptionSocial interactionLanguage processingAutismNeuroanatomical basisGroup differencesGyrusGyral volumeAdolescentsDeficitsVolumetric alterationsChildrenHealthy controlsDisordersCortical Gyrification in Autistic and Asperger Disorders: A Preliminary Magnetic Resonance Imaging Study
Jou RJ, Minshew NJ, Keshavan MS, Hardan AY. Cortical Gyrification in Autistic and Asperger Disorders: A Preliminary Magnetic Resonance Imaging Study. Journal Of Child Neurology 2010, 25: 1462-1467. PMID: 20413799, PMCID: PMC3115701, DOI: 10.1177/0883073810368311.Peer-Reviewed Original ResearchConceptsAsperger's disorderGyrification indexPreliminary magnetic resonance imaging studyMagnetic resonance imaging studyResonance imaging studyStructural magnetic resonance imagingAutism groupNeurobiological evidenceOrbitofrontal cortexIntelligence quotientCortical foldingAutismFrontal lobeCortical gyrificationMagnetic resonance imagingPreliminary findingsBrain volumeCorpus callosumDistinct syndromeControl groupDisordersImaging studiesResonance imagingInferior regionsCortical contour
2008
Brainstem volumetric alterations in children with autism
Jou RJ, Minshew NJ, Melhem NM, Keshavan MS, Hardan AY. Brainstem volumetric alterations in children with autism. Psychological Medicine 2008, 39: 1347-1354. PMID: 18812009, PMCID: PMC2888007, DOI: 10.1017/s0033291708004376.Peer-Reviewed Original ResearchMeSH KeywordsAutistic DisorderBrain StemChildChild Development Disorders, PervasiveDominance, CerebralHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleNerve Fibers, MyelinatedNerve NetOrgan SizeReference ValuesSoftwareStatistics as TopicSurveys and QuestionnairesWechsler ScalesConceptsTotal brain volumeWhite matter volumeSensory Profile questionnaireGray matter volumeMagnetic resonance imaging (MRI) scansResonance imaging scansAge-matched controlsSignificant differencesGray matter structuresBrainstem abnormalitiesBrainstem circuitrySensory deficitsSensory dysfunctionImaging scansWhite matter structuresVolumetric alterationsBrainstem volumeBrain volumeProfile questionnaireVolumetric measurementsRetarded boySensory sensitivity