The effect of preclinical Alzheimer's disease on age-related changes in intelligence in cognitively normal older adults
Harrington K, Dang C, Lim Y, Ames D, Laws S, Pietrzak R, Rainey-Smith S, Robertson J, Rowe C, Salvado O, Villemagne V, Masters C, Maruff P, Group F. The effect of preclinical Alzheimer's disease on age-related changes in intelligence in cognitively normal older adults. Intelligence 2018, 70: 22-29. DOI: 10.1016/j.intell.2018.07.004.Peer-Reviewed Original ResearchPreclinical Alzheimer's diseaseAge-related declineAlzheimer's diseaseNormal older adultsOlder adultsRisk of progressionClinical disease progressionRapid age-related declinesEarly Alzheimer's diseaseNormal age-related declineAge-related changesEffect of ageAβ groupProspective studyAβ statusDisease progressionSerial assessmentAbnormal amyloidPET neuroimagingLinear regression analysisNormal agingDiseaseIntellectual functionGreater age-related declineLinear mixed models