1993
The renal proximal tubule renin-angiotensin system.
Moe O, Alpern R, Henrich W. The renal proximal tubule renin-angiotensin system. Seminars In Nephrology 1993, 13: 552-7. PMID: 8278688.Peer-Reviewed Original ResearchConceptsProximal tubule renin-angiotensin systemProximal tubulesRenin-angiotensin systemAutosomal dominant polycystic kidney diseaseDominant polycystic kidney diseasePolycystic kidney diseaseEssential hypertensionKidney diseasePathogenetic roleRenal vasculatureJG cellsCyst growthMammalian proximal tubuleHypertensionReninTubulesComplete RASPatientsDiseaseAutocrineParacrineRAVasculature
1987
Basolateral membrane Cl/HCO3 exchange in the rat proximal convoluted tubule. Na-dependent and -independent modes.
Alpern RJ, Chambers M. Basolateral membrane Cl/HCO3 exchange in the rat proximal convoluted tubule. Na-dependent and -independent modes. The Journal Of General Physiology 1987, 89: 581-598. PMID: 2953859, PMCID: PMC2215917, DOI: 10.1085/jgp.89.4.581.Peer-Reviewed Original ResearchConceptsCl/HCO3 exchangeNa-free solutionHCO3- exchangePeritubular NaCell pHHCO3- transport mechanismsBasolateral membraneProximal tubulesCoupling of NaMammalian proximal tubuleMeq/Similar increaseAmbient ClExtracellular fluidTubulesNa dependenceCotransporterNa concentrationCl concentrationsCellsSimilar amounts