2009
Impact of antipsychotic medication on family burden in schizophrenia: Longitudinal results of CATIE trial
Perlick DA, Rosenheck RA, Kaczynski R, Swartz MS, Canive JM, Lieberman JA. Impact of antipsychotic medication on family burden in schizophrenia: Longitudinal results of CATIE trial. Schizophrenia Research 2009, 116: 118-125. PMID: 19864114, DOI: 10.1016/j.schres.2009.09.026.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntipsychotic AgentsAttitude to HealthCaregiversCost-Benefit AnalysisDouble-Blind MethodFamilyFemaleHumansLongitudinal StudiesMaleMiddle AgedPsychiatric Status Rating ScalesQuality of LifeRegression AnalysisSchizophreniaSchizophrenic PsychologySeverity of Illness IndexStatistics, NonparametricTreatment OutcomeConceptsSecond-generation antipsychoticsSecond-generation drugsFamily burdenTreatment assignmentInitial treatment assignmentSecond-generation medicationsClinical Antipsychotic TrialsEvidence of superiorityMedication changesCATIE trialInitial medicationPatient's symptomsAntipsychotic medicationAntipsychotic TrialsDaily livingFamily caregiversService useSide effectsMedicationsSecondary analysisPatientsIntervention effectivenessBurden factorsTrialsAntipsychotics
2008
Caregiver Burden and Health in Bipolar Disorder
Perlick DA, Rosenheck RA, Miklowitz DJ, Kaczynski R, Link B, Ketter T, Wisniewski S, Wolff N, Sachs G. Caregiver Burden and Health in Bipolar Disorder. The Journal Of Nervous And Mental Disease 2008, 196: 484-491. PMID: 18552626, PMCID: PMC4006696, DOI: 10.1097/nmd.0b013e3181773927.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultAffectAgedBipolar DisorderCaregiversCluster AnalysisCost of IllnessDefense MechanismsFemaleHealth BehaviorHealth StatusHumansLongitudinal StudiesMaleMiddle AgedPersonality InventoryPrejudicePsychiatric Status Rating ScalesSelf CareSocial SupportStress, PsychologicalConceptsService useBipolar disorderHealth outcomesDifferent health-related outcomesLess service useSubgroups of caregiversHealth-related outcomesBetter health outcomesAdverse health effectsCaregiver burdenHigh burdenPrimary caregiversCaregiversHealth effectsMixed effects modelsEffective caregiversOutcomesEffects modelSocial supportDisordersCoping levelsBurdenGroupHealthLow mastery
2007
Prevalence and correlates of burden among caregivers of patients with bipolar disorder enrolled in the Systematic Treatment Enhancement Program for Bipolar Disorder
Perlick DA, Rosenheck RA, Miklowitz DJ, Chessick C, Wolff N, Kaczynski R, Ostacher M, Patel J, Desai R, Group T. Prevalence and correlates of burden among caregivers of patients with bipolar disorder enrolled in the Systematic Treatment Enhancement Program for Bipolar Disorder. Bipolar Disorders 2007, 9: 262-273. PMID: 17430301, DOI: 10.1111/j.1399-5618.2007.00365.x.Peer-Reviewed Original ResearchConceptsSystematic Treatment Enhancement ProgramHealth service useOwn health needsBipolar disorderBurden caregiversService useElevated health service usePrimary caregiversMini International Neuropsychiatric InterviewMental healthMore physical health problemsAffective Disorders EvaluationCaregivers of patientsHigher caregiver burdenInternational Neuropsychiatric InterviewCorrelates of burdenPatient problem behaviorsPoor physical healthSymptoms of depressionHigh-burden caregiversMeasures of burdenHealth risk behaviorsPhysical health problemsSocial supportHealth/mental health
2006
Special Section on CATIE Baseline Data: Components and Correlates of Family Burden in Schizophrenia
Perlick D, Rosenheck R, Kaczynski R, Swartz M, Cañive J, Lieberman J. Special Section on CATIE Baseline Data: Components and Correlates of Family Burden in Schizophrenia. Psychiatric Services 2006, 57: 1117-1125. PMID: 16870962, DOI: 10.1176/ps.2006.57.8.1117.Peer-Reviewed Original ResearchConceptsMedication side effectsQuality of lifeDaily livingService useSide effectsAcute inpatient phaseImpact of symptomsPatient problem behaviorsClinical Antipsychotic TrialsPatient's symptomsCaregiver burdenInpatient phaseAntipsychotic TrialsFamily burdenFamily caregiversCaregiver dataPatient behaviorTreatment programPatients' impairmentIncorporation of skillsSymptomsIntervention effectivenessDemographic characteristicsPrevious monthSchizophrenia
2005
Use of mental health and primary care services by caregivers of patients with bipolar disorder: a preliminary study
Perlick DA, Hohenstein JM, Clarkin JF, Kaczynski R, Rosenheck RA. Use of mental health and primary care services by caregivers of patients with bipolar disorder: a preliminary study. Bipolar Disorders 2005, 7: 126-135. PMID: 15762853, DOI: 10.1111/j.1399-5618.2004.00172.x.Peer-Reviewed Original ResearchConceptsHealth service usePrimary care service useCare service useService useBipolar disorderCaregiver burdenPsychological distressMedical conditionsHealth servicesElevated health service useMental health service usePoor self-rated healthMental healthCaregivers of patientsPrimary care servicesResearch Diagnostic CriteriaLogistic regression analysisCaregiver psychological distressSelf-rated healthCaregivers of relativesSymptoms of anxietyHierarchical logistic regression analysisBurden caregiversPatient symptomatologyCaregiver depression