2022
Distinct spatio-temporal and spectral brain patterns for different thermal stimuli perception
Tayeb Z, Dragomir A, Lee J, Abbasi N, Dean E, Bandla A, Bose R, Sundar R, Bezerianos A, Thakor N, Cheng G. Distinct spatio-temporal and spectral brain patterns for different thermal stimuli perception. Scientific Reports 2022, 12: 919. PMID: 35042875, PMCID: PMC8766611, DOI: 10.1038/s41598-022-04831-w.Peer-Reviewed Original ResearchConceptsThermal stimuliAnterior cingulate cortexHot stimuliCentral brain areasCortical activityThermal stimulus conditionHealthy human subjectsInnocuous stimulationInduce early activationThermal stimulationIntensity conditioningWithdrawal reactionsPre-frontal cortexPain predictionElectroencephalography patternsParietal areasIntense stimuliClinical applicationCingulate cortexBrain areasStimulationEarly activationHuman brain’s perceptionAlpha powerElectroencephalography results
2015
Hypothermia for preventing chemotherapy-induced neuropathy – a pilot study on safety and tolerability in healthy controls
Bandla A, Sundar R, Liao L, Tan S, Lee S, Thakor N, Wilder-Smith E. Hypothermia for preventing chemotherapy-induced neuropathy – a pilot study on safety and tolerability in healthy controls. Acta Oncologica 2015, 55: 430-436. PMID: 26360921, DOI: 10.3109/0284186x.2015.1075664.Peer-Reviewed Original ResearchConceptsChemotherapy-induced peripheral neuropathyHealthy human subjectsHealthy subjectsSevere chemotherapy-induced peripheral neuropathyDose-limiting side effectReduced nerve blood flowSeverity of chemotherapy-induced peripheral neuropathyLimb hypothermiaAdjuvant weekly paclitaxelChemotherapy-induced neuropathyNerve blood flowDuration of chemotherapyBreast cancer patientsSuccess of chemotherapyInfluence of hypothermiaEffects of hypothermiaWeekly paclitaxelSignificant adverse effectsPaclitaxel chemotherapyTreatment discontinuationTransient numbnessDose-relatedNeurotoxic drugsHuman subjectsCancer subjects