2021
Interaction of Viruses with the Insect Intestine
Ma E, Zhu Y, Liu Z, Wei T, Wang P, Cheng G. Interaction of Viruses with the Insect Intestine. Annual Review Of Virology 2021, 8: 1-17. PMID: 33872516, DOI: 10.1146/annurev-virology-091919-100543.Peer-Reviewed Original ResearchConceptsSymbiotic microorganismsCell-intrinsic antiviral immunityIntrinsic antiviral immunityInsect's intestinal tractVirus-encoded componentsInsect herbivoresFoliage feedingInsect intestineHematophagous insectsPeritrophic matrixIntestinal tractInsectsBlood feedingInteraction of virusVirus invasionIntricate roleAntiviral immunityViral invasionMicroorganismsConstant threatImmunological barrierInvasionUnderlying mechanismHerbivoresNutritional status
2019
The Nuclear Matrix Protein SAFA Surveils Viral RNA and Facilitates Immunity by Activating Antiviral Enhancers and Super-enhancers
Cao L, Liu S, Li Y, Yang G, Luo Y, Li S, Du H, Zhao Y, Wang D, Chen J, Zhang Z, Li M, Ouyang S, Gao X, Sun Y, Wang Z, Yang L, Lin R, Wang P, You F. The Nuclear Matrix Protein SAFA Surveils Viral RNA and Facilitates Immunity by Activating Antiviral Enhancers and Super-enhancers. Cell Host & Microbe 2019, 26: 369-384.e8. PMID: 31513772, DOI: 10.1016/j.chom.2019.08.010.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphatasesAnimalsAntiviral AgentsChromosomal Proteins, Non-HistoneDNA Topoisomerases, Type IDNA VirusesHEK293 CellsHeLa CellsHerpesvirus 1, HumanHeterogeneous-Nuclear Ribonucleoprotein UHost-Pathogen InteractionsHumansImmunity, InnateInterferon Regulatory Factor-3Interferon Regulatory Factor-7MiceNuclear Matrix-Associated ProteinsProtein Serine-Threonine KinasesReceptors, Pattern RecognitionRNA VirusesRNA, Double-StrandedRNA, ViralVirusesConceptsImmune gene transcriptionViral RNAViral RNA sensorsChromatin remodelingTrigger innate immune responsesSuper enhancersGene transcriptionExtranuclear localizationRNA virusesInnate immune responseAntiviral genesDsRNA sensorsRNA sensorsViral dsRNAAntiviral stateAntiviral responseType I IFNDsRNAVSV infectionRobust antiviral responseRNAEnhancerI IFNImmune responseHSV-1