Identification of a new isoform of the murine Sh2d1a gene and its functional implications
Wu L, Lu P, Ma W, Chu C, Xu H, Qi H. Identification of a new isoform of the murine Sh2d1a gene and its functional implications. Science China Life Sciences 2013, 57: 81-87. PMID: 24369347, DOI: 10.1007/s11427-013-4584-z.Peer-Reviewed Original ResearchConceptsNon-functional isoformsSrc homologyNew isoformAmino acid proteinIntracellular adaptor proteinPhosphotyrosine bindingSH2D1A geneAdaptor proteinAlternative splicingSap proteinsNew exonsProtein stabilityX chromosomeSplice isoformsFunctional analysisCryptic exonFunction mutationsAmino acidsFunctional implicationsStructural regionsIsoformsSAP-2GenesHematopoietic systemProtein