Featured Publications
A negative regulator of MAP kinase causes depressive behavior
Duric V, Banasr M, Licznerski P, Schmidt HD, Stockmeier CA, Simen AA, Newton SS, Duman RS. A negative regulator of MAP kinase causes depressive behavior. Nature Medicine 2010, 16: 1328-1332. PMID: 20953200, PMCID: PMC3066515, DOI: 10.1038/nm.2219.Peer-Reviewed Original Research
2023
Prefrontal cortex astroglia modulate anhedonia-like behavior
Codeluppi S, Xu M, Bansal Y, Lepack A, Duric V, Chow M, Muir J, Bagot R, Licznerski P, Wilber S, Sanacora G, Sibille E, Duman R, Pittenger C, Banasr M. Prefrontal cortex astroglia modulate anhedonia-like behavior. Molecular Psychiatry 2023, 28: 4632-4641. PMID: 37696873, PMCID: PMC10914619, DOI: 10.1038/s41380-023-02246-1.Peer-Reviewed Original ResearchGlial fibrillary acidic proteinAnhedonia-like behaviorPrefrontal cortexCell depletionDiphtheria toxin administrationDepressive-like behaviorChronic stress modelTreatment of depressionDiphtheria toxin receptorFibrillary acidic proteinDevelopment of anhedoniaCortical astrogliaToxin administrationDesigner receptorsCell activityAcidic proteinViral expressionToxin receptorDesigner drugsExperimental depletionAstrogliaDeficitsReceptorsDepressionCritical role