Cytomegalovirus infection drives avidity selection of natural killer cells
Adams N, Lumaquin D, Santosa E, Whitlock B, Jackson B, Le Luduec J, Sottile R, Weizman O, Huse M, Hsu K, Sun J. Cytomegalovirus infection drives avidity selection of natural killer cells. The Journal Of Immunology 2019, 202: 76.3-76.3. DOI: 10.4049/jimmunol.202.supp.76.3.Peer-Reviewed Original ResearchNK cell poolNK cellsNatural killer cellsKiller cellsImmune responseNK cell effector functionsNK cell populationHuman NK cellsIFN-γ productionCell effector functionsCell poolSecondary immune responseAntiviral immune responseHuman CMV infectionGreater receptor affinityGreater clonal expansionCMV infectionCytomegalovirus infectionInnate lymphocytesAvidity maturationInfectious challengeMCMV infectionReceptor expressionVirus infectionEffector functions