2023
Scenario Decision-Making About Plasma and Platelet Transfusion for Intracranial Monitor Placement: Cross-Sectional Survey of Pediatric Intensivists and Neurosurgeons
Nellis M, Karam O, Aldave G, Rocque B, Bauer D, Network I. Scenario Decision-Making About Plasma and Platelet Transfusion for Intracranial Monitor Placement: Cross-Sectional Survey of Pediatric Intensivists and Neurosurgeons. Pediatric Critical Care Medicine 2023, 25: e205-e213. PMID: 37966339, PMCID: PMC10994730, DOI: 10.1097/pcc.0000000000003414.Peer-Reviewed Original ResearchTraumatic brain injuryInternational normalized ratioICP monitor placementPlatelet transfusionsPediatric intensivistsPlasma transfusionPediatric neurosurgeonsCase-based scenariosPlatelet countIntracranial pressurePediatric Acute Lung InjurySevere traumatic brain injury×109/LMonitor placementAcute lung injuryPlatelet count thresholdCross-sectional surveySepsis InvestigatorsLung injuryNormalized ratioTransfusion decisionsBrain injuryTransfusionIntensivistsViscoelastic testing
2022
Ketamine Boluses Are Associated with a Reduction in Intracranial Pressure and an Increase in Cerebral Perfusion Pressure: A Retrospective Observational Study of Patients with Severe Traumatic Brain Injury
Dengler BA, Karam O, Barthol CA, Chance A, Snider LE, Mundy CM, Bounajem MT, Johnson WC, Maita MM, Mendez-Gomez PM, Seifi A, Hafeez S. Ketamine Boluses Are Associated with a Reduction in Intracranial Pressure and an Increase in Cerebral Perfusion Pressure: A Retrospective Observational Study of Patients with Severe Traumatic Brain Injury. Critical Care Research And Practice 2022, 2022: 3834165. PMID: 35637760, PMCID: PMC9148235, DOI: 10.1155/2022/3834165.Peer-Reviewed Original ResearchCerebral perfusion pressureSevere traumatic brain injuryTraumatic brain injuryKetamine bolusGlasgow Coma ScaleRefractory intracranial pressureIntracranial pressureBrain injuryPerfusion pressureRetrospective reviewSingle tertiary referral centerTraumatic brain injury populationSustained ICPTertiary referral centerNeurointensive care unitRetrospective observational studyBolus of ketamineSingle-institution studyBrain injury populationIntracranial pressure monitorSystemic hypotensionReferral centerSedative medicationsAdequate sedationComa Scale
2020
Ketamine Boluses Decrease Intracranial Pressure and Improve Cerebral Perfusion Pressure in Patients with Severe Traumatic Brain Injury
Dengler B, Karam O, Barthol C, Hafeez S. Ketamine Boluses Decrease Intracranial Pressure and Improve Cerebral Perfusion Pressure in Patients with Severe Traumatic Brain Injury. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_450.Peer-Reviewed Original Research
2013
International survey on plasma transfusion practices in critically ill children
Karam O, Tucci M, Lacroix J, Rimensberger PC, Network C. International survey on plasma transfusion practices in critically ill children. Transfusion 2013, 54: 1125-1132. PMID: 24032693, DOI: 10.1111/trf.12393.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryPediatric critical care physiciansPlasma transfusion practicesInternational normalized ratioCritical care physiciansPlasma transfusionTransfusion practiceCare physiciansRed blood cell transfusion practicesAbnormal international normalized ratioPediatric critical care unitCardiac postoperative patientsTransfusion practice patternsSeptic shock patientsDemographic characteristicsCritical care unitsPartial thromboplastin timeProportion of physiciansFallot correctionNonbleeding patientsMinor bleedingShock patientsTransfusion thresholdPostoperative patientsSeptic shock