2023
Bleeding in Critically Ill Children With Malignancy or Hematopoietic Cell Transplant: A Single-Center Prospective Cohort Study
Levasseur J, Fikse L, Mauguen A, Killinger J, Karam O, Nellis M. Bleeding in Critically Ill Children With Malignancy or Hematopoietic Cell Transplant: A Single-Center Prospective Cohort Study. Pediatric Critical Care Medicine 2023, 24: e602-e610. PMID: 37678406, PMCID: PMC10843653, DOI: 10.1097/pcc.0000000000003374.Peer-Reviewed Original ResearchConceptsProspective cohort studyBleeding episodesSevere bleedingIll childrenCohort studyCell transplantIncidence rateLaboratory valuesMinimal bleedingRadiation therapySingle-center prospective cohort studyAssociated Patient CharacteristicsHigher PICU mortalityNew bleeding episodesOnly laboratory valueHematopoietic cell transplantCritically Ill ChildrenLow platelet countSevere bleeding episodesStem cell transplantPatient demographic dataSpecialized cancer hospitalModerate bleeding episodesYears of ageLonger PICU
2017
Diagnosis and Management of Necrotizing Enterocolitis: An International Survey of Neonatologists and Pediatric Surgeons
Valpacos M, Arni D, Keir A, Aspirot A, Wilde JCH, Beasley S, De Luca D, Pfister RE, Karam O. Diagnosis and Management of Necrotizing Enterocolitis: An International Survey of Neonatologists and Pediatric Surgeons. Neonatology 2017, 113: 170-176. PMID: 29241163, DOI: 10.1159/000484197.Peer-Reviewed Original ResearchConceptsPediatric surgeonsBloody stoolManagement of NECPortal venous gasLow platelet countGut wall thicknessAbdominal tendernessGastric residualsAbdominal distensionVenous gasIntestinal pneumatosisNecrotizing enterocolitisSerious complicationsClinical featuresPlatelet countClinical examinationTreatment strategiesLactate levelsIntestinal movementNeonatologistsAntibiotic spectrumSurgeonsLimited evidenceNECEnterocolitis