Transfusion practices for pediatric oncology and hematopoietic stem cell transplantation patients: Data from the National Heart Lung and Blood Institute Recipient Epidemiology and Donor Evaluation Study‐III (REDS‐III)
Goel R, Nellis ME, Karam O, Hanson SJ, Tormey CA, Patel RM, Birch R, Sachais BS, Sola‐Visner M, Hauser RG, Luban NLC, Gottschall J, Josephson CD, Hendrickson JE, Karafin MS, Study‐IV‐Pediatric F. Transfusion practices for pediatric oncology and hematopoietic stem cell transplantation patients: Data from the National Heart Lung and Blood Institute Recipient Epidemiology and Donor Evaluation Study‐III (REDS‐III). Transfusion 2021, 61: 2589-2600. PMID: 34455598, DOI: 10.1111/trf.16626.Peer-Reviewed Original ResearchConceptsInternational normalized ratioBlood Institute Recipient EpidemiologyDonor Evaluation Study-IIINational Heart LungTransfusion practicePediatric oncologyRecipient EpidemiologyHSCT patientsPlasma transfusionRed blood cellsPlatelet countHeart LungHematopoietic stem cell transplantation patientsHematopoietic stem cell transplant patientsMedian international normalized ratioStem cell transplant patientsStem cell transplantation patientsLower INR valuesPre-transfusion HbMedian platelet countMulticenter retrospective studyCell transplant patientsCell transplantation patientsStudy IIIAcute myeloid leukemiaTransfusion Practices in Pediatric Cardiac Surgery Requiring Cardiopulmonary Bypass: A Secondary Analysis of a Clinical Database
Hanson SJ, Karam O, Birch R, Goel R, Patel RM, Sola-Visner M, Sachais BS, Hauser RG, Luban NLC, Gottschall J, Josephson CD, Hendrickson JE, Karafin MS, Nellis ME, Lung A. Transfusion Practices in Pediatric Cardiac Surgery Requiring Cardiopulmonary Bypass: A Secondary Analysis of a Clinical Database. Pediatric Critical Care Medicine 2021, 22: 978-987. PMID: 34261944, PMCID: PMC8570986, DOI: 10.1097/pcc.0000000000002805.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseBiventricular surgeryCardiopulmonary bypass surgeryHeart diseaseMedian internationalBypass surgeryMembrane oxygenationPlatelet countBlood componentsVentricular surgeryHemoglobin valuesBlood Institute Recipient EpidemiologyDonor Evaluation Study-IIIHigher median platelet countNormal international normalized ratioIntraoperative platelet transfusionLimited physiologic reserveMultiple blood productsPretransfusion platelet countU.S. hospitalsMedian platelet countBlood component transfusionBlood component usageExtracorporeal membrane oxygenationInternational normalized ratioTransfusion practices in a large cohort of hospitalized children
Nellis ME, Goel R, Hendrickson JE, Birch R, Patel RM, Karafin MS, Hanson SJ, Sachais BS, Hauser RG, Luban NLC, Gottschall J, Sola‐Visner M, Josephson CD, Karam O, Study‐IV‐Pediatric F. Transfusion practices in a large cohort of hospitalized children. Transfusion 2021, 61: 2042-2053. PMID: 33973660, DOI: 10.1111/trf.16443.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBlood Component TransfusionBlood TransfusionChildChild, PreschoolDatasets as TopicDiagnosis-Related GroupsFemaleHospital MortalityHospitals, CommunityHospitals, TeachingHumansInfantInfant, NewbornInpatientsMaleProcedures and Techniques UtilizationRetrospective StudiesUnited StatesConceptsRBC transfusionCardiopulmonary bypassTransfusion practiceHospitalized childrenInpatient encountersBlood componentsLarge cohortHospital settingBlood Institute Recipient EpidemiologyDonor Evaluation Study-IIIPatient blood management initiativesDiagnostic categoriesFrequency of transfusionInstitutional transfusion guidelinesCohort of patientsInternational normalized ratioPercent of encountersNational Heart LungPediatric hospital settingYears of ageSubset of childrenRecipient EpidemiologyTransfusion guidelinesRed blood cellsEntire cohortVariation in Neonatal Transfusion Practice
Patel RM, Hendrickson JE, Nellis ME, Birch R, Goel R, Karam O, Karafin MS, Hanson SJ, Sachais BS, Hauser RG, Luban NLC, Gottschall J, Josephson CD, Sola-Visner M, National Heart L, Mast A, Hod E, Custer B, Vichinsky E, Spencer B, Mathew S, Harris D, Busch M, Norris P, Ness P, Kleinman S, Tamburro R, Glynn S, Malkin K. Variation in Neonatal Transfusion Practice. The Journal Of Pediatrics 2021, 235: 92-99.e4. PMID: 33836184, PMCID: PMC8316298, DOI: 10.1016/j.jpeds.2021.04.002.Peer-Reviewed Original ResearchConceptsWeeks of gestationEntire cohortPretransfusion hemoglobinPlatelet countNeonatal transfusionBlood Institute Recipient EpidemiologyDonor Evaluation Study-IIIInternational normalized ratio (INR) valuesHematologic valuesNeonatal transfusion practicesPretransfusion platelet countRetrospective cohort studyBlood product transfusionGestational age groupsPatient blood managementNational Heart LungRecipient EpidemiologyInitial hospitalizationProduct transfusionCohort studyRed blood cellsGestational ageTransfusion practiceHeart LungBlood management