2013
Patient–Ventilator Asynchrony During Noninvasive Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist in Infants and Children
Vignaux L, Grazioli S, Piquilloud L, Bochaton N, Karam O, Levy-Jamet Y, Jaecklin T, Tourneux P, Jolliet P, Rimensberger PC. Patient–Ventilator Asynchrony During Noninvasive Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist in Infants and Children. Pediatric Critical Care Medicine 2013, 14: e357-e364. PMID: 23863816, DOI: 10.1097/pcc.0b013e3182917922.Peer-Reviewed Original ResearchConceptsAsynchrony eventsVentilator assistNoninvasive ventilationPremature cyclingVentilatory assistPressure supportAsynchrony indexNoninvasive pressure support ventilationProspective randomized cross-over studyPositive end-expiratory pressureRandomized cross-over studyMaximum airway pressurePressure support ventilationEnd-expiratory pressureCross-over studyPatient-ventilator asynchronyPatient-ventilator synchronyAdjusted Ventilatory AssistType of asynchronyAirway pressureSupport ventilationClinical impactInspiratory timeTrigger delayDouble triggeringOptimizing Patient-Ventilator Synchrony During Invasive Ventilator Assist in Children and Infants Remains a Difficult Task*
Vignaux L, Grazioli S, Piquilloud L, Bochaton N, Karam O, Jaecklin T, Levy-Jamet Y, Tourneux P, Jolliet P, Rimensberger PC. Optimizing Patient-Ventilator Synchrony During Invasive Ventilator Assist in Children and Infants Remains a Difficult Task*. Pediatric Critical Care Medicine 2013, 14: e316-e325. PMID: 23842584, DOI: 10.1097/pcc.0b013e31828a8606.Peer-Reviewed Original ResearchConceptsAsynchrony eventsVentilatory assistExpiratory triggerInspiratory timeAsynchrony indexNeonatal intensive care unitIntensive care unitPressure support modePatient-ventilator synchronyPressure supportMedian asynchrony indexCare unitCrossover studyMechanical ventilationVentilated childrenVentilator assistUniversity HospitalPremature cyclingClinical impactRandom orderVentilation periodIneffective effortsFurther studiesChildrenSupport mode
2010
Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study
Karam O, Tucci M, Bateman ST, Ducruet T, Spinella PC, Randolph AG, Lacroix J. Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study. Critical Care 2010, 14: r57. PMID: 20377853, PMCID: PMC2887178, DOI: 10.1186/cc8953.Peer-Reviewed Original ResearchConceptsPediatric intensive care unitMultiple organ dysfunction syndromeRed blood cell unitsOrgan dysfunction syndromeDysfunction syndromeIll childrenPICU lengthClinical outcomesOdds ratioObservational studyMultiple logistic regression modelProspective observational studyWorse clinical outcomesPrimary outcome measureIntensive care unitNorth American centersCell unitsLogistic regression modelsSecondary outcomesConsecutive patientsOrgan dysfunctionCare unitMedian lengthProspective studyClinical impact