2012
Immunofluorescent localization of the Rab-GAP protein TBC1D4 (AS160) in mouse kidney
Lier N, Gresko N, Di Chiara M, Loffing-Cueni D, Loffing J. Immunofluorescent localization of the Rab-GAP protein TBC1D4 (AS160) in mouse kidney. Histochemistry And Cell Biology 2012, 138: 101-112. PMID: 22466139, DOI: 10.1007/s00418-012-0944-1.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsFluorescent Antibody TechniqueGTPase-Activating ProteinsKidneyKidney Tubules, DistalLoop of HenleMiceMice, Inbred StrainsConceptsIntracellular traffickingRab-GTPase activating proteinInsulin-dependent traffickingParietal epithelial cellsRenal transport proteinsExtracellular fluid homeostasisGlucose transporter GLUT4Epithelial sodium channel ENaCDeficient miceImmunohistochemical studyRabbit polyclonal antibodySkeletal muscle cellsBowman's capsuleWater channel AQP2Proximal tubulesRenal ionSpecific marker proteinsKidney homogenatesHenle's loopSodium channel ENaCFluid homeostasisThick limbMuscle cellsMouse kidney homogenatesMouse kidney
2010
In vivo nuclear translocation of mineralocorticoid and glucocorticoid receptors in rat kidney: differential effect of corticosteroids along the distal tubule
Ackermann D, Gresko N, Carrel M, Loffing-Cueni D, Habermehl D, Gomez-Sanchez C, Rossier B, Loffing J. In vivo nuclear translocation of mineralocorticoid and glucocorticoid receptors in rat kidney: differential effect of corticosteroids along the distal tubule. American Journal Of Physiology. Renal Physiology 2010, 299: f1473-f1485. PMID: 20861076, DOI: 10.1152/ajprenal.00437.2010.Peer-Reviewed Original ResearchConceptsAldosterone-sensitive distal nephronThick ascending limbGlucocorticoid receptorLate distal convoluted tubuleLow-dose corticosterone replacementSegment-specific cellsNuclear translocationDietary NaCl loadingDistal convoluted tubuleKidneys of ratsDehydrogenase type 2Proximal tubule cellsAldosterone replacementMineralocorticoid selectivityPlasma aldosteroneCorticosteroid effectsCorticosterone replacementControl ratsDistal tubulesDistal nephronConvoluted tubulesNaCl loadingCorticosterone levelsAscending limbHigh doses