Gut microbiome strain-sharing within isolated village social networks
Beghini F, Pullman J, Alexander M, Shridhar S, Prinster D, Singh A, Matute Juárez R, Airoldi E, Brito I, Christakis N. Gut microbiome strain-sharing within isolated village social networks. Nature 2024, 1-9. PMID: 39567691, DOI: 10.1038/s41586-024-08222-1.Peer-Reviewed Original ResearchVillage social networksClusters of speciesMicrobiome sequencing dataGut microbiome compositionStrain-level dataMicrobiome biologySequence dataSpecies-levelSocial networksMicrobial sharingPhenotypic impactMicrobiome compositionMicrobiomeSocial network mapsCo-villagersSocial nicheExtended social environmentPeripheral peopleGutSocial connectionsSocial environmentFace-to-face social networksClusters of peopleRelationship typesVillageEnvironmental, socioeconomic, and health factors associated with gut microbiome species and strains in isolated Honduras villages
Shridhar S, Beghini F, Alexander M, Singh A, Juárez R, Brito I, Christakis N. Environmental, socioeconomic, and health factors associated with gut microbiome species and strains in isolated Honduras villages. Cell Reports 2024, 43: 114442. PMID: 38968070, PMCID: PMC11290354, DOI: 10.1016/j.celrep.2024.114442.Peer-Reviewed Original ResearchGut microbiomeGut microbiome speciesSpecies-level profilingSequenced microbiomesMetagenomic dataMicrobiome speciesHost phenotypeBacterial speciesHuman phenotypesMesoamerican highlandsSeveral speciesGutSpeciesMicrobiomePhenotypeAssociated with body mass indexCommunity-based cohortBody mass indexConsistent with previous findingsSocioeconomic factorsIsolated villagesHousehold wealthMass indexHostStrain