2018
Fish Oil and Perioperative Bleeding
Akintoye E, Sethi P, Harris WS, Thompson PA, Marchioli R, Tavazzi L, Latini R, Pretorius M, Brown NJ, Libby P, Mozaffarian D. Fish Oil and Perioperative Bleeding. Circulation Cardiovascular Quality And Outcomes 2018, 11: e004584. PMID: 30571332, PMCID: PMC6376981, DOI: 10.1161/circoutcomes.118.004584.Peer-Reviewed Original ResearchConceptsBleeding Academic Research Consortium bleedingPerioperative bleedingFish oil supplementationFish oil groupLower riskPrimary outcomeFish oilMean ageOil supplementationOil groupBleeding Academic Research ConsortiumPlasma phospholipid omega-3Coronary artery bypass graftMajor perioperative bleedingChest tube outputPlacebo-controlled trialAcademic Research ConsortiumArtery bypass graftTreatment of hypertriglyceridemiaAbsolute risk differenceParticipants' mean ageHealth care professionalsFatty acid levelsBleeding definitionsHemostasis definition
2013
Plasma Phospholipid Omega‐3 Fatty Acids and Incidence of Postoperative Atrial Fibrillation in the OPERA Trial
Wu JH, Marchioli R, Silletta MG, Macchia A, Song X, Siscovick DS, Harris WS, Masson S, Latini R, Albert C, Brown NJ, Lamarra M, Favaloro RR, Mozaffarian D. Plasma Phospholipid Omega‐3 Fatty Acids and Incidence of Postoperative Atrial Fibrillation in the OPERA Trial. Journal Of The American Heart Association 2013, 2: e000397. PMID: 24145742, PMCID: PMC3835252, DOI: 10.1161/jaha.113.000397.Peer-Reviewed Original ResearchConceptsFish oil supplementationMorning of surgeryPostoperative atrial fibrillationCardiac surgeryOil supplementationDocosapentaenoic acidAtrial fibrillationDocosahexaenoic acidEicosapentaenoic acidShort-term fish oil supplementationPUFA levelsOmega-3 fatty acidsCardiac surgery patientsPlasma phospholipid nPostoperative day 10Substantial interindividual variabilityOPERA trialPoAF episodesPlacebo supplementationPrimary endpointSecondary endpointsHospital dischargeSurgery patientsAntiarrhythmic potentialFatty acids