Escape from the Acute Wolff-Chaikoff Effect Is Associated with a Decrease in Thyroid Sodium/Iodide Symporter Messenger Ribonucleic Acid and Protein*
Eng P, Cardona G, Fang S, Previti M, Alex S, Carrasco N, Chin W, Braverman L. Escape from the Acute Wolff-Chaikoff Effect Is Associated with a Decrease in Thyroid Sodium/Iodide Symporter Messenger Ribonucleic Acid and Protein*. Endocrinology 1999, 140: 3404-3410. DOI: 10.1210/en.140.8.3404.Peer-Reviewed Original ResearchAcute Wolff-Chaikoff effectThyroid peroxidase mRNANIS mRNAIodide administrationWolff-Chaikoff effectThyroid peroxidaseIodide transportTSH receptorNIS proteinIodide ingestionIntrathyroidal iodine contentIodine-induced hypothyroidismSerum TSH levelsOrganification of iodideAcute experimentsIodide-induced changesMessenger ribonucleic acidPlasma iodide levelsTSH levelsHashimoto's thyroiditisChronic experimentsSerum T4Plasma iodide concentrationsSodium/iodide symporterCyclophilin mRNAEscape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid sodium/iodide symporter messenger ribonucleic acid and protein.
Eng P, Cardona G, Fang S, Previti M, Alex S, Carrasco N, Chin W, Braverman L. Escape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid sodium/iodide symporter messenger ribonucleic acid and protein. Endocrinology 1999, 140: 3404-10. PMID: 10433193, DOI: 10.1210/endo.140.8.6893.Peer-Reviewed Original ResearchConceptsAcute Wolff-Chaikoff effectThyroid peroxidase mRNANIS mRNAIodide administrationWolff-Chaikoff effectThyroid peroxidaseIodide transportTSH receptorNIS proteinIodide ingestionIntrathyroidal iodine contentIodine-induced hypothyroidismSerum TSH levelsOrganification of iodideAcute experimentsIodide-induced changesMessenger ribonucleic acidPlasma iodide levelsTSH levelsHashimoto's thyroiditisChronic experimentsSerum T4Plasma iodide concentrationsSodium/iodide symporterHormone measurements