2019
Cortical Excitability Dynamics During Fear Processing
Chirumamilla V, Gonzalez-Escamilla G, Koirala N, Bonertz T, von Grotthus S, Muthuraman M, Groppa S. Cortical Excitability Dynamics During Fear Processing. Frontiers In Neuroscience 2019, 13: 568. PMID: 31275095, PMCID: PMC6593288, DOI: 10.3389/fnins.2019.00568.Peer-Reviewed Original ResearchFrontal theta powerFear processingTranscranial magnetic stimulationTheta powerVisual cuesWeighted phase lag indexAlpha powerPrefrontal cortexRight dorsomedial prefrontal cortexCortical excitabilityCortical excitability dynamicsAversive unconditioned stimulusInstructed fear paradigmDorsomedial prefrontal cortexFrontal lobeVisual cue onsetStress coping behaviorTheta power changesStructural MRI scanningAlpha frequency bandCue onsetCoping behaviorsFear paradigmOccipital lobeUnconditioned stimulus
2017
Frontal Lobe Connectivity and Network Community Characteristics are Associated with the Outcome of Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson’s Disease
Koirala N, Fleischer V, Glaser M, Zeuner K, Deuschl G, Volkmann J, Muthuraman M, Groppa S. Frontal Lobe Connectivity and Network Community Characteristics are Associated with the Outcome of Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson’s Disease. Brain Topography 2017, 31: 311-321. PMID: 28986718, DOI: 10.1007/s10548-017-0597-4.Peer-Reviewed Original ResearchConceptsDeep brain stimulationDiffusion-weighted imagingPostoperative clinical outcomesClinical responseParkinson's diseaseSTN-DBSClinical outcomesSubthalamic nucleusBrain stimulationSubthalamic nucleus deep brain stimulationNon-motor symptomsOptimal clinical responseConnectivity profilesPre-intervention predictorsEvidence-based stateIndependent predictorsPD patientsTherapy optionsClinical effectivenessCingulate gyrusFrontal lobe connectivityCerebral regionsT MRI scannerCerebral networksPrefrontal cortex