2019
Gray matter integrity predicts white matter network reorganization in multiple sclerosis
Radetz A, Koirala N, Krämer J, Johnen A, Fleischer V, Gonzalez‐Escamilla G, Cerina M, Muthuraman M, Meuth S, Groppa S. Gray matter integrity predicts white matter network reorganization in multiple sclerosis. Human Brain Mapping 2019, 41: 917-927. PMID: 32026599, PMCID: PMC7268008, DOI: 10.1002/hbm.24849.Peer-Reviewed Original ResearchConceptsDeep gray matter volumesGray matter volumeMultiple sclerosisGray matter integrityMatter volumeWhite matter networksEarly relapsing-remitting multiple sclerosisRelapsing-remitting multiple sclerosisTime pointsGray matter atrophyDeep gray matter structuresCognitive performanceMiddle temporal cortexGray matter structuresGray matter regionsDisability progressionBrain stemMatter damageSignificant atrophyMatter atrophyDeep gray matter regionsCortical thicknessTemporal cortexTissue damageAtrophyStructural brain network fingerprints of focal dystonia
Chirumamilla V, Dresel C, Koirala N, Gonzalez-Escamilla G, Deuschl G, Zeuner K, Muthuraman M, Groppa S. Structural brain network fingerprints of focal dystonia. Therapeutic Advances In Neurological Disorders 2019, 12: 1756286419880664. PMID: 31798688, PMCID: PMC6859688, DOI: 10.1177/1756286419880664.Peer-Reviewed Original ResearchBSP patientsHFS patientsBoNT treatmentHealthy controlsFocal dystoniaHemifacial spasmSensorimotor cortexFrontal cortexTemporal cortexStructural magnetic resonance imagingReduced connectivityGray matter volumeDifferent brain regionsSymptomatic reductionMovement disordersStructural brain networksGraph-based network analysisPatientsMatter volumeBlepharospasmDystoniaParietal cortexResonance imagingBrain regionsDecreased connectivity
2015
Testing the effects of pre-processing on voxel based morphometry analysis
Chaitanya C, Koirala N, Mideksa K, Anwar A, Schmidt G, Deuschl G, Groppa S, Muthuraman M. Testing the effects of pre-processing on voxel based morphometry analysis. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2015, 2015: 4302-4305. PMID: 26737246, DOI: 10.1109/embc.2015.7319346.Peer-Reviewed Original ResearchConceptsGray matter volumeGray matter differencesDifferent time pointsTime pointsMagnetic resonance imagesBotulinum toxin injectionEvidence-based therapiesStructural grey matter differencesVoxel-wise comparisonBase therapyToxin injectionCross-sectional data analysisBotulinum toxinMatter volumeRespective musclesMorphometry analysisLongitudinal data analysisPatientsLongitudinal analysisResonance imagesInjectionBrainTreatmentSecond aimStatistical analysis