Frailty, Neurocognitive Impairment, or Both in Predicting Poor Health Outcomes Among Adults Living With Human Immunodeficiency Virus
Erlandson KM, Perez J, Abdo M, Robertson K, Ellis RJ, Koletar SL, Kalayjian R, Taiwo B, Palella FJ, Tassiopoulos K. Frailty, Neurocognitive Impairment, or Both in Predicting Poor Health Outcomes Among Adults Living With Human Immunodeficiency Virus. Clinical Infectious Diseases 2018, 68: 131-138. PMID: 29788039, PMCID: PMC6293002, DOI: 10.1093/cid/ciy430.Peer-Reviewed Original ResearchMeSH KeywordsAdultClinical Decision RulesCognitive DysfunctionFrailtyHIV InfectionsHumansLongitudinal StudiesMaleMiddle AgedPrognosisConceptsPoor health outcomesHuman immunodeficiency virusNeurocognitive impairmentHealth outcomesImmunodeficiency virusPrevalence ratiosMedian CD4 countOutcomes of fallsOverlap of frailtyPresence of frailtyHIV-1 RNACopies/mLPoisson regression modelsCD4 countRecurrent fallsMedian ageIADL limitationsObservational studyDaily livingAdjusted modelPLWHFrailtySignificant associationGreater riskMost participants