2018
Frailty, Neurocognitive Impairment, or Both in Predicting Poor Health Outcomes Among Adults Living With Human Immunodeficiency Virus
Erlandson KM, Perez J, Abdo M, Robertson K, Ellis RJ, Koletar SL, Kalayjian R, Taiwo B, Palella FJ, Tassiopoulos K. Frailty, Neurocognitive Impairment, or Both in Predicting Poor Health Outcomes Among Adults Living With Human Immunodeficiency Virus. Clinical Infectious Diseases 2018, 68: 131-138. PMID: 29788039, PMCID: PMC6293002, DOI: 10.1093/cid/ciy430.Peer-Reviewed Original ResearchConceptsPoor health outcomesHuman immunodeficiency virusNeurocognitive impairmentHealth outcomesImmunodeficiency virusPrevalence ratiosMedian CD4 countOutcomes of fallsOverlap of frailtyPresence of frailtyHIV-1 RNACopies/mLPoisson regression modelsCD4 countRecurrent fallsMedian ageIADL limitationsObservational studyDaily livingAdjusted modelPLWHFrailtySignificant associationGreater riskMost participants
2017
Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults
Tassiopoulos K, Abdo M, Wu K, Koletar SL, Palella FJ, Kalayjian R, Taiwo B, Erlandson KM. Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults. AIDS 2017, 31: 2287-2294. PMID: 28991026, PMCID: PMC5654616, DOI: 10.1097/qad.0000000000001613.Peer-Reviewed Original ResearchConceptsRecurrent fallsFrailty assessmentGrip strengthSelf-reported weight lossLogistic regressionContribution of frailtyMulticenter cohort studyLow physical activityRisk of fallsPotential target populationOlder HIVCohort studyBaseline frailtyPeripheral neuropathyEffect modificationFrail individualsMultivariable modelFrail personsPhysical activityClinical careMultinomial logistic regressionHIVNonfrail individualsPrefrailSignificant association