2020
Randomised controlled trial of sugammadex or neostigmine for reversal of neuromuscular block on the incidence of pulmonary complications in older adults undergoing prolonged surgery
Togioka BM, Yanez D, Aziz MF, Higgins JR, Tekkali P, Treggiari MM. Randomised controlled trial of sugammadex or neostigmine for reversal of neuromuscular block on the incidence of pulmonary complications in older adults undergoing prolonged surgery. British Journal Of Anaesthesia 2020, 124: 553-561. PMID: 32139135, DOI: 10.1016/j.bja.2020.01.016.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCholinesterase InhibitorsDelayed Emergence from AnesthesiaDouble-Blind MethodFemaleHumansIntraoperative PeriodLung DiseasesMaleNeostigmineNeuromuscular BlockadeNeuromuscular JunctionNeuromuscular Nondepolarizing AgentsPatient ReadmissionPostoperative ComplicationsRocuroniumSugammadexConceptsPostoperative pulmonary complicationsResidual neuromuscular blockPulmonary complicationsDay hospital readmissionNeuromuscular blockPrimary endpointHospital readmissionDay hospital readmission rateOlder adultsHospital readmission ratesPhase 1 recoveryRocuronium reversalNeostigmine groupSecondary endpointsSugammadex groupReadmission ratesResidual paralysisSurgical closureSugammadexComplicationsNeostigmineLarger studySurgeryIncidenceEndpoint
2011
Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury
Chaiwat O, Vavilala MS, Philip S, Malakouti A, Neff MJ, Deem S, Treggiari MM, Wang J, Lang JD. Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury. Journal Of Critical Care 2011, 26: 144-151. PMID: 20869200, DOI: 10.1016/j.jcrc.2010.08.002.Peer-Reviewed Original ResearchMeSH KeywordsAcute Lung InjuryAdolescentAdultAgedAged, 80 and overAPACHECritical IllnessFemaleGuideline AdherenceHospital MortalityHumansInjury Severity ScoreIntraoperative PeriodLength of StayMaleMiddle AgedPositive-Pressure RespirationPractice Guidelines as TopicRetrospective StudiesRisk FactorsTidal VolumeYoung AdultConceptsAcute respiratory distress syndromeAcute lung injuryALI/acute respiratory distress syndromeLTV ventilationLung injuryClinical outcomesLow tidal volume ventilation strategyALI/ARDS diagnosisLow tidal volume ventilationVolume ventilation strategyRespiratory distress syndromeTidal volume ventilationARDS diagnosisHospital mortalityIntraoperative adherenceHospital lengthSecondary outcomesSurgical patientsDistress syndromeIll patientsVolume ventilationImproved oxygenationPatient outcomesRetrospective analysisMAIN OUTCOME