2014
Assessment of Circulating Blood Volume with Fluid Administration Targeting Euvolemia or Hypervolemia
Joffe AM, Khandelwal N, Hallman MR, Treggiari MM. Assessment of Circulating Blood Volume with Fluid Administration Targeting Euvolemia or Hypervolemia. Neurocritical Care 2014, 22: 82-88. PMID: 25142828, DOI: 10.1007/s12028-014-9993-8.Peer-Reviewed Original ResearchConceptsSubgroup of patientsBlood volumeHV groupDay 5Fluid administrationFluid balanceDelayed ischemic neurologic deficitsCrystalloid fluid administrationIschemic neurologic deficitCumulative fluid balanceML/Higher fluid balanceT-testStudent's t-testProphylactic hypervolemiaICU admissionICU stayResultsTwenty patientsNeurologic deficitsCerebral vasospasmClinical trialsHypervolemiaNormovolemiaBVA-100Concurrent group
2010
Current Practices of Triple-H Prophylaxis and Therapy in Patients with Subarachnoid Hemorrhage
Meyer R, Deem S, David Yanez N, Souter M, Lam A, Treggiari MM. Current Practices of Triple-H Prophylaxis and Therapy in Patients with Subarachnoid Hemorrhage. Neurocritical Care 2010, 14: 24-36. PMID: 20838932, DOI: 10.1007/s12028-010-9437-z.Peer-Reviewed Original ResearchConceptsNeurointensive care unitSubarachnoid hemorrhagePercent of respondentsProphylactic hypervolemiaHemodilution therapySymptomatic vasospasmCerebral vasospasmDedicated neurointensive care unitsDiagnostic approachMean arterial pressureCentral venous cathetersSystolic blood pressureEvidence of vasospasmAneurysmal subarachnoid hemorrhageNeurocritical Care SocietyTarget of therapyBackgroundMedical managementLonger ICULack of evidenceVenous cathetersArterial pressureBlood pressureCare unitHalf of respondentsPressure titration
2009
Which H is the most important in triple-H therapy for cerebral vasospasm?
Treggiari MM, Deem S. Which H is the most important in triple-H therapy for cerebral vasospasm? Current Opinion In Critical Care 2009, 15: 83-86. PMID: 19276798, DOI: 10.1097/mcc.0b013e32832922d1.Peer-Reviewed Original ResearchConceptsCerebral vasospasmSubarachnoid hemorrhageCirculatory volume expansionNew randomized trialsCerebral blood flowHemodynamic managementRandomized trialsHemodynamic variablesHypervolemic hemodilutionRegistry databaseBlood flowPaucity of informationVasospasmPhysiologic dataHemorrhagePhysiological studiesLow levelsHypertensionComplicationsHemodilutionTherapyRecent literatureTrialsAccuracy of transcranial Doppler ultrasonography and single-photon emission computed tomography in the diagnosis of angiographically demonstrated cerebral vasospasm.
Kincaid MS, Souter MJ, Treggiari MM, Yanez ND, Moore A, Lam AM. Accuracy of transcranial Doppler ultrasonography and single-photon emission computed tomography in the diagnosis of angiographically demonstrated cerebral vasospasm. Journal Of Neurosurgery 2009, 110: 67-72. PMID: 18821830, DOI: 10.3171/2008.4.17520.Peer-Reviewed Original ResearchConceptsAnterior cerebral arteryMiddle cerebral arteryTranscranial Doppler ultrasonographyPosterior cerebral arteryTCD ultrasonographyBasilar arteryCerebral arteryDoppler ultrasonographyOdds ratioAbsence of vasospasmInstitutional review board approvalRecords of patientsReview board approvalSingle photon emissionRoutine clinical useCerebral angiographyCerebral vasospasmMean ageSubarachnoid hemorrhageVascular territoriesSPECT evaluationVasospasmRelative oddsBoard approvalUltrasonography
2003
Systematic review of the prevention of delayed ischemic neurological deficits with hypertension, hypervolemia, and hemodilution therapy following subarachnoid hemorrhage.
Treggiari MM, Walder B, Suter PM, Romand JA. Systematic review of the prevention of delayed ischemic neurological deficits with hypertension, hypervolemia, and hemodilution therapy following subarachnoid hemorrhage. Journal Of Neurosurgery 2003, 98: 978-84. PMID: 12744357, DOI: 10.3171/jns.2003.98.5.0978.Peer-Reviewed Original ResearchConceptsDelayed ischemic neurological deficitsIschemic neurological deficitsHemodilution therapyNeurological deficitsSubarachnoid hemorrhageMethodological qualitySystematic reviewSummary relative risk estimatesRisk of deathMajor end pointsInternal validity scoreRelative risk estimatesStudy methodological qualityRandom-effects modelClinical vasospasmSymptomatic vasospasmCerebral vasospasmRegister searchMAIN OUTCOMEValidity scoresReference listsPaucity of informationVasospasmEnd pointRisk estimatesCervical Sympathetic Block to Reverse Delayed Ischemic Neurological Deficits After Aneurysmal Subarachnoid Hemorrhage
Treggiari MM, Romand JA, Martin JB, Reverdin A, Rüfenacht DA, de Tribolet N. Cervical Sympathetic Block to Reverse Delayed Ischemic Neurological Deficits After Aneurysmal Subarachnoid Hemorrhage. Stroke 2003, 34: 961-966. PMID: 12649526, DOI: 10.1161/01.str.0000060893.72098.80.Peer-Reviewed Original ResearchConceptsCervical sympathetic blockAneurysmal subarachnoid hemorrhageSympathetic blockCerebral perfusionNeurological statusCerebral vasospasmSubarachnoid hemorrhageMaximal medical treatmentCervical sympathetic chainIschemic neurological deficitsSuperior cervical ganglionConfirmatory angiographyHorner's signIschemic deficitsLocoregional treatmentNeurological deficitsSevere vasospasmStandard therapyCerebral angiographyConsecutive patientsSympathetic chainLocoregional anesthesiaCervical ganglionInitial hemorrhageModerate symptoms