2024
Opioid Dose Variation in Cardiac Surgery: A Multicenter Study of Practice.
Fisher C, Janda A, Zhao X, Deng Y, Bardia A, Yanez N, Burns M, Aziz M, Treggiari M, Mathis M, Lin H, Schonberger R. Opioid Dose Variation in Cardiac Surgery: A Multicenter Study of Practice. Anesthesia & Analgesia 2024 PMID: 39167548, DOI: 10.1213/ane.0000000000007128.Peer-Reviewed Original ResearchCardiac surgeryOpioid doseDose variationIntraoperative opioid administrationIntraoperative opioid doseHigh-dose opioidsAdult cardiac surgerySurgical differencesOpioid-freeOpioid administrationOpioid useMultimodal analgesiaAnalgesic techniquesCardiopulmonary bypassMulticenter studyFentanyl equivalentsSufentanil infusionSurgical patientsOpioidSurgeryAnesthetic techniqueCardiac casesAttending anesthesiologistPatientsDose
2021
Factor VIII inhibitor bypass activity (FEIBA) for the reduction of transfusion in cardiac surgery: a randomized, double-blind, placebo-controlled, pilot trial
Sera VA, Stevens AE, Song HK, Rodriguez VM, Tibayan FA, Treggiari MM. Factor VIII inhibitor bypass activity (FEIBA) for the reduction of transfusion in cardiac surgery: a randomized, double-blind, placebo-controlled, pilot trial. Pilot And Feasibility Studies 2021, 7: 137. PMID: 34215339, PMCID: PMC8252226, DOI: 10.1186/s40814-021-00873-5.Peer-Reviewed Original ResearchFactor Eight Inhibitor Bypassing ActivityCardiac surgeryPilot trialTransfusion requirementsRescue therapyLarge trialsProtocol adherenceBlood productsHigh-risk cardiac surgeryProthrombin complex concentrate administrationPlacebo-controlled pilot trialFactor VIII inhibitor bypass activityLarge pivotal trialsReduction of transfusionBlood product transfusionEnd of CPBTertiary referral hospitalHypothermic circulatory arrestTermination of CPBPost-cardiopulmonary bypassProthrombin complex concentrateBlinded administrationProduct transfusionResultsTwenty patientsStudy drug
2020
Randomized Pilot Trial of Acute Normovolemic Hemodilution in Pediatric Cardiac Surgery Patients
Harris WM, Treggiari MM, LeBlanc A, Giacomuzzi C, You JJ, Muralidaran A, Shen I. Randomized Pilot Trial of Acute Normovolemic Hemodilution in Pediatric Cardiac Surgery Patients. World Journal For Pediatric And Congenital Heart Surgery 2020, 11: 452-458. PMID: 32645767, DOI: 10.1177/2150135120923627.Peer-Reviewed Original ResearchConceptsPediatric cardiac surgery patientsAcute normovolemic hemodilutionCardiac surgery patientsSecondary end pointsSurgery patientsEnd pointPostoperative outcomesUsual careBlood transfusionCardiac surgeryNormovolemic hemodilutionHeart surgeryBlood productsPilot trialPediatric heart surgery patientsMarkers of morbidityAllogenic blood transfusionPrimary end pointHeart surgery patientsLong-term morbidityBlood conservation strategiesWorse postoperative outcomesPediatric heart surgeryIntensive care unitBlood component therapy
2019
Electromagnetic Interference with Protocolized Electrosurgery Dispersive Electrode Positioning in Patients with Implantable Cardioverter Defibrillators.
Schulman PM, Treggiari MM, Yanez ND, Henrikson CA, Jessel PM, Dewland TA, Merkel MJ, Sera V, Harukuni I, Anderson RB, Kahl E, Bingham A, Alkayed N, Stecker EC. Electromagnetic Interference with Protocolized Electrosurgery Dispersive Electrode Positioning in Patients with Implantable Cardioverter Defibrillators. Anesthesiology 2019, 130: 530-540. PMID: 30601218, DOI: 10.1097/aln.0000000000002571.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillatorCardiac surgeryNoncardiac surgeryCardioverter defibrillatorAntitachycardia therapyMonopolar electrosurgeryElectrode positioningInappropriate antitachycardia therapyProspective cohort studyHeart Rhythm SocietyExpert clinical opinionAcademic medical centerPaucity of dataCohort studyCurrent management recommendationsProtocolized ApproachMedical CenterClinical opinionSurgeryPatientsUmbilicusTherapyDefibrillatorDispersive electrodeAmerican Society
2018
Right Ventricular Systolic Performance Determined by 2D Speckle-Tracking Echocardiography and Acute Kidney Injury After Cardiac Surgery
Yockelson SR, Heitner SB, Click S, Geleto G, Treggiari MM, Hutchens MP. Right Ventricular Systolic Performance Determined by 2D Speckle-Tracking Echocardiography and Acute Kidney Injury After Cardiac Surgery. Journal Of Cardiothoracic And Vascular Anesthesia 2018, 33: 725-731. PMID: 30316640, PMCID: PMC6379134, DOI: 10.1053/j.jvca.2018.09.012.Peer-Reviewed Original ResearchConceptsAcute kidney injuryRV systolic pressureSpeckle tracking echocardiographyCardiac surgeryAKI groupTransthoracic echocardiogramKidney injurySystolic pressureMyocardial performanceElevated RV systolic pressureRight ventricular myocardial performanceCardiovascular intensive care unitRetrospective observational cohort studyRV myocardial performancePreoperative serum creatinineCardiac surgery patientsCentral venous pressureObservational cohort studyVentricular systolic performanceSerum creatinine valuesVentricular myocardial performanceBody mass indexIntensive care unitIntravascular volume statusSpeckle-tracking analysis
2014
Variation in Tracheal Reintubations Among Patients Undergoing Cardiac Surgery Across Washington State Hospitals
Khandelwal N, Dale CR, Benkeser DC, Joffe AM, Yanez ND, Treggiari MM. Variation in Tracheal Reintubations Among Patients Undergoing Cardiac Surgery Across Washington State Hospitals. Journal Of Cardiothoracic And Vascular Anesthesia 2014, 29: 551-559. PMID: 25802193, PMCID: PMC4427545, DOI: 10.1053/j.jvca.2014.11.009.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAirway ExtubationAirway ManagementCardiac Surgical ProceduresCohort StudiesCoronary Artery BypassCritical CareDatabases, FactualFemaleHealth SurveysHumansIntubation, IntratrachealMaleMiddle AgedRetrospective StudiesRisk FactorsSocioeconomic FactorsTreatment FailureTreatment OutcomeWashingtonConceptsIntensive care unitCardiac surgeryWashington State hospitalsNonfederal hospitalsState HospitalAcute care daysGreater hospital volumeOdds of reintubationCoronary artery bypassRetrospective cohort studyPatient-level characteristicsMultivariate logistic regressionSignificant heterogeneityValvular surgeryArtery bypassCohort studyHospital factorsHospital volumePatient characteristicsTracheal reintubationCare unitProcedure characteristicsHospital characteristicsCare daysReintubation
2013
A Greater Analgesia, Sedation, Delirium Order Set Quality Score Is Associated With a Decreased Duration of Mechanical Ventilation in Cardiovascular Surgery Patients
Dale CR, Bryson CL, Fan VS, Maynard C, Yanez ND, Treggiari MM. A Greater Analgesia, Sedation, Delirium Order Set Quality Score Is Associated With a Decreased Duration of Mechanical Ventilation in Cardiovascular Surgery Patients. Critical Care Medicine 2013, 41: 2610-2617. PMID: 23989171, DOI: 10.1097/ccm.0b013e31829a6ee7.Peer-Reviewed Original ResearchConceptsCardiac surgery patientsMechanical ventilationSurgery patientsCardiac surgeryAverage durationMean durationOrder setsCardiac surgery hospitalCardiovascular surgery patientsDelivery of analgesiaRetrospective cohort studyMultivariable linear regression modelsImproved patient outcomesShorter mean durationNon-federal hospitalsQuality scoresWashington State hospitalsShorter average durationHospital painCohort studyGreater analgesiaHospital factorsPatient factorsDelirium careSurgery Hospital
2011
Cardioplegia and ventricular late potentials in cardiac surgical patients
Schütz N, Romand J, Yanez ND, Treggiari MM, Bendjelid K. Cardioplegia and ventricular late potentials in cardiac surgical patients. Journal Of Clinical Monitoring And Computing 2011, 25: 269. PMID: 21932050, DOI: 10.1007/s10877-011-9305-1.Peer-Reviewed Original ResearchConceptsOccurrence of LPCardiac surgical patientsCardiopulmonary bypassCardiac surgeryLate potentialsSurgical patientsAbnormal signal-averaged electrocardiogramPrevious myocardial infarctionSignal-averaged electrocardiogramConclusionsThe present studyVentricular late potentialsCPB durationMyocardial infarctionPre-post scoresMyocardial ischemiaVentricular tachycardiaElective patientsSudden deathPatientsSurgeryCardioplegiaMcNemar testPositive scoreScoresNegative scores