2020
Big Data in Transplantation Practice-the Devil Is in the Detail-Fontan-associated Liver Disease.
Kim M, Nguyen A, Lo M, Kumar S, Bucuvalas J, Glynn E, Hoffman M, Fischer R, Emamaullee J. Big Data in Transplantation Practice-the Devil Is in the Detail-Fontan-associated Liver Disease. Transplantation 2020, 105: 18-22. PMID: 32639398, DOI: 10.1097/tp.0000000000003308.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overBig DataChildChild, PreschoolData CollectionData MiningDatabases, FactualFemaleFontan ProcedureHeart Defects, CongenitalHumansInfantInfant, NewbornLiver DiseasesLiver TransplantationMaleMiddle AgedRisk AssessmentRisk FactorsTreatment OutcomeYoung AdultConceptsFontan-associated liver diseasePatients post-FontanPost-FontanLiver diseaseSingle-ventricle heart diseaseHeart-liver transplantationProgressive hepatic fibrosisMultiple health systemsConsequences of chronic exposureFontan procedureFontan RegistryNoncardiac complicationsHeart-liverTime of heartFontan hemodynamicsLiver transplantationHepatocellular carcinomaFontanHepatic fibrosisIndividual patientsHeart diseasePatientsHealth systemAffected childrenTransplantation
2019
Immunologic benefit of maternal donors in pediatric living donor liver transplantation
Kim M, Akbari O, Genyk Y, Kohli R, Emamaullee J. Immunologic benefit of maternal donors in pediatric living donor liver transplantation. Pediatric Transplantation 2019, 23: e13560. PMID: 31402535, DOI: 10.1111/petr.13560.Peer-Reviewed Original ResearchConceptsLDLT recipientsPediatric LDLT recipientsPediatric LDLTImmune tolerancePost-transplantPrimary diagnosis of biliary atresiaImpact of graft typeMechanisms of immune toleranceDiagnosis of biliary atresiaOperational toleranceImprove outcomesLong-term follow-upPediatric LDLT patientsWithdrawal of immunosuppressionRegulatory T cellsImproving allograft survivalTime post-transplantDonor liver transplantationDeceased donor recipientsMaternal-fetal microchimerismRate of rejectionLDLT patientsAllograft survivalBiliary atresiaPatient survival