2014
Science Signaling Podcast: 23 September 2014
Simons M, VanHook A. Science Signaling Podcast: 23 September 2014. Science Signaling 2014, 7 DOI: 10.1126/scisignal.2005857.Peer-Reviewed Original ResearchTGF-β signalingMesenchymal transitionReceptor FGFR1Line blood vesselsFibroblast growth factor (FGF) pathwayEndothelial cellsTGF-β receptorCell biologyPolarized cellsGrowth factor pathwaysScience SignalingSignalingBlood vesselsFactor pathwayVascular homeostasisFGFNormal functionCellsFGFR1EndMTNormal conditionsMicroRNAsSenior authorBiologyHomeostasis
2008
FGF mediates maintenance of vascular integrity in a Csk dependent manner
Murakami M, Zhuang Z, Moodie K, Stan R, Simons M. FGF mediates maintenance of vascular integrity in a Csk dependent manner. The FASEB Journal 2008, 22: 329.5-329.5. DOI: 10.1096/fasebj.22.1_supplement.329.5.Peer-Reviewed Original ResearchInhibition of FGFVE-cadherinVE-cadherin mutantCo-immunoprecipitation experimentsDominant-negative formCell-cell contactVE-cadherin complexVE-cadherin internalizationVE-cadherin stabilizationTotal expression levelsVascular integrityCSK associationFGF signalingP120-cateninEC monolayer permeabilitySrc activationChimera proteinTransgenic expressionFGF inhibitionFGFAdult vasculatureExpression levelsFGF-R1ProteinTie2 promoter