A Specific Subset of Transient Receptor Potential Vanilloid-Type Channel Subunits in Caenorhabditis elegans Endocrine Cells Function as Mixed Heteromers to Promote Neurotransmitter Release
Jose AM, Bany IA, Chase DL, Koelle MR. A Specific Subset of Transient Receptor Potential Vanilloid-Type Channel Subunits in Caenorhabditis elegans Endocrine Cells Function as Mixed Heteromers to Promote Neurotransmitter Release. Genetics 2007, 175: 93-105. PMID: 17057248, PMCID: PMC1774992, DOI: 10.1534/genetics.106.065516.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAnimals, Genetically ModifiedBiological TransportCaenorhabditis elegansCaenorhabditis elegans ProteinsEndocrine GlandsFemaleIon ChannelsMolecular Sequence DataNerve Tissue ProteinsNeurosecretory SystemsOvipositionSequence Homology, Amino AcidTRPV Cation ChannelsConceptsOCR-2Neuroendocrine cellsEgg-laying defectsTRPV channel OSM-9Heteromeric channelsG protein GDominant negative mutantTransient receptor potential channelsEndocrine cell functionOSM-9Heteromeric partnerTRPV channelsSensory neuronsSingle knockoutDetectable functionOCR-1Premature eggsSensory transductionChannel subunitsDetectable roleSubunit compositionCell functionRelease of neurotransmittersNeurotransmitter releaseSubunit combinations