1993
Transport defects of rabbit medullary thick ascending limb cells in obstructive nephropathy.
Hwang S, Haas M, Harris H, Silva P, Yalla S, Sullivan M, Otuechere G, Kashgarian M, Zeidel M. Transport defects of rabbit medullary thick ascending limb cells in obstructive nephropathy. Journal Of Clinical Investigation 1993, 91: 21-28. PMID: 8380811, PMCID: PMC329990, DOI: 10.1172/jci116173.Peer-Reviewed Original ResearchConceptsMedullary thick ascending limbNa-K-ATPase activityNa-K-ATPaseBasolateral Na-K-ATPaseObstructed kidneysObstructive nephropathyUreteral obstructionLuminal NaRelease of obstructionThick ascending limbMajor sodium transportersUntreated kidneysTransport defectSpecific monoclonal antibodiesSodium transport defectsControl animalsAscending limbOuter medullaKidneyApical NaMarked reductionMonoclonal antibodiesMTAL cellsInhibitory effectObstruction
1976
Ion transport and structure of urinary bladder epithelium of Amphiuma
Mullen T, Kashgarian M, Biemesderfer D, Giebisch G, Biber T. Ion transport and structure of urinary bladder epithelium of Amphiuma. American Journal Of Physiology 1976, 231: 501-508. PMID: 961904, DOI: 10.1152/ajplegacy.1976.231.2.501.Peer-Reviewed Original Research
1971
Role of peritubular protein concentration in sodium reabsorption
Weinman E, Kashgarian M, Hayslett J. Role of peritubular protein concentration in sodium reabsorption. American Journal Of Physiology 1971, 221: 1521-1528. PMID: 5124298, DOI: 10.1152/ajplegacy.1971.221.5.1521.Peer-Reviewed Original ResearchAccelerated reabsorption in the proximal tubule produced by volume depletion
Weiner M, Weinman E, Kashgarian M, Hayslett J. Accelerated reabsorption in the proximal tubule produced by volume depletion. Journal Of Clinical Investigation 1971, 50: 1379-1385. PMID: 5090054, PMCID: PMC292075, DOI: 10.1172/jci106620.Peer-Reviewed Original ResearchConceptsProximal tubulesFiltration rateVolume depletionIntrinsic reabsorptive capacitySodium-free dietGlomerular filtration rateProximal fluid reabsorptionAdministration of furosemideReabsorption of fluidTechnique of micropunctureAldosterone secretionRenal responseSodium depletionDistal tubulesReabsorptive capacityBody weightChronic depletionFluid reabsorptionMarked fallExtracellular volumePlasma volumeClinical phenomenaReabsorptionTubulesPresent experiments